phenyl N-(4-bromophenyl)carbamate synthesis
- Product Name:phenyl N-(4-bromophenyl)carbamate
- CAS Number:50882-29-6
- Molecular formula:C13H10BrNO2
- Molecular Weight:292.13
1885-14-9
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106-40-1
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50882-29-6
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Yield:50882-29-6 97%
Reaction Conditions:
in ethyl acetate at 0 - 20; for 2 h;
Steps:
10.1 Step 1: Synthesis of (4-bromophenyl) phenyl carbamate
At 0° C., phenyl chloroformate (1.60 ml, 1.50 mmol) was slowly added dropwise to a solution of 4-bromoaniline (2.00 g, 11.63 mmol) in EtOAc (25 mL), and reacted at room temperature for 2 h.The reaction solution was diluted with EtOAc (50mL), and then diluted with H2Wash with O (20mL×3) and saturated NaCl solution (20mL), anhydrous Na2SO4Dry and concentrate under reduced pressure to obtain a pink solid (3.33 g, 97%).
References:
CN113072538,2021,A Location in patent:Paragraph 0369; 0371-0373
14917-59-0
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108-95-2
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50882-29-6
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$28.60/250mg