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ChemicalBook CAS DataBase List (S)-4-(2-PYRROLIDINYLMETHYL)MORPHOLINE
91790-91-9

(S)-4-(2-PYRROLIDINYLMETHYL)MORPHOLINE synthesis

9synthesis methods
-

Yield:91790-91-9 99%

Reaction Conditions:

with HCl (g) in methanol;

Steps:

94.B B.

B. (S)-4-Pyrrolidin-2-ylmethyl-morpholine HCl (g) was introduced into a solution of (S)-2-morpholin-4-ylmethyl-pyrrolidine-1-carboxylic acid tert-butyl ester (400 mg, 1.47 mmol) in MeOH. After 5 min., the reaction solution was concentrated under reduced pressure to give a white solid (300 mg, 99%). MS: 170.9 (MH+); HPLC Rf: n.d.; HPLC purity: n.d.

References:

US2002/42409,2002,A1

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