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Spirosta-3,5-diene,(25R)- synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: cyclohexanone; aluminum isopropoxide / toluene / 10 h / Reflux
2.1: C19H26ClIrN3O(1+)*Cl(1-) / water / 0.17 h / 80 °C
2.2: 4 h / 80 °C

References:

Li, Jide;Tang, Weiping;Ren, Demin;Xu, Jiaxi;Yang, Zhanhui [Green Chemistry,2019,vol. 21,# 8,p. 2088 - 2094]