STEAROYL CHLORIDE synthesis
- Product Name:STEAROYL CHLORIDE
- CAS Number:112-76-5
- Molecular formula:C18H35ClO
- Molecular Weight:302.92
57-11-4
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$6.00/100g
112-76-5
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$40.32/25G
Yield:112-76-5 99%
Reaction Conditions:
with thionyl chloride in toluene at 20;Reflux;
Steps:
14.b
b. Preparation of stearoyl chloride (Compound 4) [00238] A 2 L three-necked round-bottomed flask equipped with a mechanical stirrer, reflux condenser, heating mantle and pressure equalizing addition funnel was charged with stearic acid (97.6 g, 0.343 mol) and 750 mL of toluene. The mixture was stirred, heated to refluxing. Thionyl chloride (26.3 mL, 42.8 g, 0.360 mol) was added over a period of 30 minutes. The mixture was refluxed for an additional three hours and at ambient temperature over night. A small amount (12.0 g) of unreacted stearic acid was removed by vacuum filtration and the toluene removed under reduced pressure to afford 90.3 g (99.0% based on recovered starting material) of stearoyl chloride (Compound 4) as a light yellow oil.
References:
AMYRIS, INC.;OHLER, Nicholas;FISHER, Karl;HONG, Jin Ki WO2012/141783, 2012, A1 Location in patent:Page/Page column 76
822-16-2
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112-76-5
239 suppliers
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112-76-5
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57-11-4
1185 suppliers
$6.00/100g
112-76-5
239 suppliers
$40.32/25G