thieno[3,2-d]isothiazole-5-carboxylic acid synthesis
- Product Name:thieno[3,2-d]isothiazole-5-carboxylic acid
- CAS Number:74598-12-2
- Molecular formula:C6H3NO2S2
- Molecular Weight:185.22
14345-97-2
241 suppliers
$6.00/1g
74598-12-2
7 suppliers
inquiry
Yield:-
Steps:
Multi-step reaction with 9 steps
1: 89 percent / n-butyl-lithium / diethyl ether / 1.) reflux, 2 h, 2.) - 70 deg C
2: SOCl2
4: 94 percent / bromine / CCl4 / 5 h / Heating; Irradiation
5: 90 percent / H2SO4 / 4 h
6: 92 percent / NH2OH / ethanol / 2 h / 0 °C
7: 79 percent / NaHS, DMSO / acetone / 2 h / Heating
8: 74 percent / dimethylsulfoxide / 0.08 h / 170 °C / other 2,3-disubstituted thiophens; various conditions
9: 90 percent / H2SO4 / H2O / 1 h / 100 °C
References:
Clarke, Kenneth;Fox, William Richard;Scrowston, Richard M. [Journal of the Chemical Society. Perkin transactions I,1980,p. 1029 - 1037]
![ethyl thieno[3,2-d]isothiazole-5-carboxylate](/CAS2/GIF/74598-11-1.gif)
74598-11-1
9 suppliers
inquiry
74598-12-2
7 suppliers
inquiry
74598-03-1
16 suppliers
inquiry
74598-12-2
7 suppliers
inquiry
91505-29-2
3 suppliers
inquiry
74598-12-2
7 suppliers
inquiry
74598-04-2
15 suppliers
inquiry
74598-12-2
7 suppliers
inquiry