trans-3'-Hydroxy Cotinine Benzoate synthesis
- Product Name:trans-3'-Hydroxy Cotinine Benzoate
- CAS Number:146275-16-3
- Molecular formula:C17H16N2O3
- Molecular Weight:296.32
500-22-1
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146275-16-3
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Yield:-
Steps:
Multi-step reaction with 7 steps
1: 94 percent / toluene / 20 h / Heating
2: 80 percent / CH2Cl2 / 168 h / Heating
3: 76 percent / aq. HCl / ethanol / 5 h / 20 °C
4: H2O / 2 h / 20 °C
5: 9.3 mg / Et3SiH; CF3CO2H / CH2Cl2 / 0.5 h / Heating
6: 54 percent / H2 / Pd/C / aq. ethanol / 1.5 h
7: DEAD; PPh3 / toluene / 0.08 h / 20 °C
References:
Tamura, Osamu;Kanoh, Ayano;Yamashita, Masayuki;Ishibashi, Hiroyuki [Tetrahedron,2004,vol. 60,# 44,p. 9997 - 10003]
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146275-16-3
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146275-16-3
10 suppliers
$105.00/5mg