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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
ChemicalBook CAS DataBase List Trifluoromethanesulfonamide
421-85-2

Trifluoromethanesulfonamide synthesis

9synthesis methods
15.39 trifluoromethanesulfonyl chloride dissolved in 103 g of anhydrous isopropyl ether is charged to a reactor. The medium is cooled to 5 °C. and the ammonia is added slowly over 2 hours. After 5 hours of stirring at 5° C., 24.8 g of water are added to dissolve the salts. The medium is then acidified by adding 20.7 g of a 36% aqueous hydrochloric acid solution.   
After a further addition of 13 g of water, the phases are separated. The aqueous phase is washed with 50 g of isopropyl ether. The organic phases are combined and the solvent is removed under reduced pressure.
10.15 g of a white solid of trifluoromethanesulfonamide are thus obtained.
421-83-0 Synthesis
Trifluoromethanesulfonyl chloride

421-83-0
248 suppliers
$22.39/1G

Trifluoromethanesulfonamide

421-85-2
230 suppliers
$9.00/250mg

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Yield:421-85-2 96%

Steps:

1 Step 1:

Step 1: Trifluoromethylsulphonamide : The title compound was prepared using the same procedure as described in Example 12, Step 1, replacing isopropylsulphonyl chloride with trifluoromethylsulphonyl chloride. The compound was purified by trituration with hexane to give the product (8.5g, 96%) as a colourless solid. mp 116-119°C.

References:

EP514133,1992,A1

2926-29-6 Synthesis
Sodium trifluoromethanesulfinate

2926-29-6
307 suppliers
$6.00/5g

Trifluoromethanesulfonamide

421-85-2
230 suppliers
$9.00/250mg

References
358-23-6 Synthesis
Trifluoromethanesulfonic anhydride

358-23-6
618 suppliers
$10.00/1g

Trifluoromethanesulfonamide

421-85-2
230 suppliers
$9.00/250mg

References
TRIFLUOROMETHANESULFONYL FLUORIDE

335-05-7
43 suppliers
inquiry

Trifluoromethanesulfonamide

421-85-2
230 suppliers
$9.00/250mg

References
Bromonium, [4-(trifluoromethyl)phenyl][[(trifluoromethyl)sulfonyl]amino]-, inner salt

957188-75-9
0 suppliers
inquiry

Trifluoromethanesulfonamide

421-85-2
230 suppliers
$9.00/250mg

402-43-7 Synthesis
4-Bromobenzotrifluoride

402-43-7
444 suppliers
$6.00/10g

References

Trifluoromethanesulfonamide Related Search:

Trimethylsilyl trifluoromethanesulfonate Trifluoromethanesulfonic acid Trifluoromethanesulfonic anhydride Borane-trimethylamine complex (Trifluoromethyl)trimethylsilane Zinc trifluoromethanesulfonate Ethyl trifluoromethanesulfonate Sodium trifluoromethanesulfonate COPPER(II) TRIFLUOROMETHANESULFONATE Lithium trifluoromethanesulfonate