tris(4-(pyridin-4-ylethynyl)phenyl)amine synthesis
- Product Name:tris(4-(pyridin-4-ylethynyl)phenyl)amine
- CAS Number:359647-66-8
- Molecular formula:C39H24N4
- Molecular Weight:548.63
15854-87-2
320 suppliers
$6.00/1g
189178-09-4
67 suppliers
$51.00/250mg
359647-66-8
4 suppliers
inquiry
Yield:359647-66-8 85%
Reaction Conditions:
Stage #1: p-iodopyridine;4,4',4''-triethynyltriphenylamine in 1,4-dioxane;lithium hydroxide monohydrate; for 0.166667 h;Inert atmosphere;Sonogashira Cross-Coupling;
Stage #2: with [1,1'-bis(diphenylphosphino)ferrocene]dichloropalladium(II);copper (I) iodide;tetrakis-(triphenylphosphine)-palladium in 1,4-dioxane;lithium hydroxide monohydrate at 90; for 12 h;Inert atmosphere;
Steps:
4.3. General procedure for Sonogashira cross-coupling(chromophores 4-6)
General procedure: The appropriate mono-, di- or tri-acetylene TPA derivative(200 mg) and 4-iodopyridine were dissolved in a mixture ofdioxane/piperidine (25 mL, 4/1). Ar was bubbled through themixture for 10 min and [Pd(PPh3)4] and CuI were added. The reactionmixture was stirred at 90° C for 12 h. The cooled reactionmixture was diluted with H2O (50 mL) and extracted with CH2Cl2(2 50 mL). The combined organic extracts were thenwashed withsaturated NH4Cl solution, brine, and dried. Finally, the solventswere evaporated under vacuum and the crude productwas purifiedby column chromatography (SiO2, appropriate eluent).
References:
Tydlitát, Ji?í;Achelle, Sylvain;Rodríguez-López, Julián;Pytela, Old?ich;Mikysek, Tomá?;Cabon, Nolwenn;Robin-le Guen, Fran?oise;Miklík, David;R??i?ková, Zdeňka;Bure?, Filip [Dyes and Pigments,2017,vol. 146,p. 467 - 478]
2510-22-7
128 suppliers
$18.00/100mg
4181-20-8
205 suppliers
$9.00/1g
359647-66-8
4 suppliers
inquiry
19524-06-2
496 suppliers
$6.00/5g
189178-09-4
67 suppliers
$51.00/250mg
359647-66-8
4 suppliers
inquiry
603-34-9
317 suppliers
$24.89/5g
359647-66-8
4 suppliers
inquiry
4181-20-8
205 suppliers
$9.00/1g
359647-66-8
4 suppliers
inquiry