Vinylmagnesium chloride synthesis

Yield:-

Reaction Conditions:

with magnesium in tert-butyl methyl ether at 50; for 8 h;Inert atmosphere;

Steps:

3 Example 3 Vinyl chloride Grignard solution
Add 24.3g (1.0mol) of magnesium powder to the reaction flask equipped with stirring, thermometer and dry reflux tube, add 500ml of dry methyl tert-butyl ether, stir, replace the reaction system with dry nitrogen and raise the temperature to 50°C. Slowly pass in vinyl chloride and add 1 to 2 iodine pellets at the same time. After the reaction is initiated, the temperature of the system rises and the color of iodine disappears. Control the feeding rate of vinyl chloride. After the reaction solution is slightly boiling for 8 hours, the reaction is ended and the heating is turned off. And stirring, the reaction solution is cooled to room temperature and left to stand, the supernatant is the vinyl chloride Grignard solution, which is directly used in the next step.

References:

Shanghai Modern Hasen (Business Qiu) Pharmaceutical Co., Ltd.;Henan Food Medicine Shenping Chayan Center;Wang Yingli;Zhang Pei;Jin Jianwen;Chen Hong;Wu Quan;Wei Wei;Guo Xuguang;Qin Fangqing;Wang Haixia;Liu Li CN111393275, 2020, A Location in patent:Paragraph 0061; 0086-0087

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