vorapaxar sulfate M-9 synthesis
- Product Name:vorapaxar sulfate M-9
- CAS Number:900161-11-7
- Molecular formula:C29H32N2O5
- Molecular Weight:488.57
899809-61-1
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Yield:-
Steps:
Multi-step reaction with 3 steps
1.1: 4-methyl-morpholine; pivaloyl chloride / tetrahydrofuran / -5 - 0 °C
1.2: 3 h / 5 °C
2.1: Pd/CaCO3; quinoline; hydrogen / ethyl acetate / 15 °C
3.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / 1-methyl-pyrrolidin-2-one / 16 h / 40 - 140 °C
References:
CN107540564,2018,A