| Identification | More | [Name]
Tebufenozide | [CAS]
112410-23-8 | [Synonyms]
3,5-dimethylbenzoic acid 1-(1,1-dimethylethyl)-2-(4-ethylbenzoyl)hydrazide
CONFIRM
MIMIC
TEBUFENOCIDE
TEBUFENOZIDE
rh5992
TEBUFENOZIDE PESTANAL, 100 MG
3,5-DIMETHYLBENZOIC ACID-(1,1-DIMETHYLETHYL)-2-(4-ETHYLBENZOYL)HYDRAZIDE
Benzoic acid, 3,5-dimethyl-, 1-(1,1-dimethylethyl)-2-(4-ethylbenzoyl)hydrazide
tebufenozide(ansi,iso,bsi)confirm
N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide
Tebufenozide suspension
Conform
N-tert-butyl-N-(4-ethylbenzoly)-3,5-dimetthyl benzohydrazide
3,5-Dimethylbenzoic acid N-tert-butyl-N-(4-ethylbenzoyl)hydrazide
616-076-00-9 | [EINECS(EC#)]
412-850-3 | [Molecular Formula]
C22H28N2O2 | [MDL Number]
MFCD00467963 | [Molecular Weight]
352.47 | [MOL File]
112410-23-8.mol |
| Safety Data | Back Directory | [Hazard Codes ]
N | [Risk Statements ]
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
UN 3077 | [WGK Germany ]
2 | [HazardClass ]
9 | [PackingGroup ]
III | [HS Code ]
29280000 | [Hazardous Substances Data]
112410-23-8(Hazardous Substances Data) | [Toxicity]
LD50 orally in rats, mice: >5000 mg/kg; dermally in rats: >5000 mg/kg; LD50 in honey bees (96 hr, contact): >234 mg/bee; LC50 in mallard duck (8-day dietary): >5000 mg/kg; LC50 in rainbow trout (96 hr): 5.7 mg/l (Heller) |
| Questions And Answer | Back Directory | [General Description]
Tebufenozide is an ecdysone insecticide, which causes the premature molting of insects by interfering with the normal development of insects. It has high insecticidal activity and high selectivity, being effective in treatment of all lepidopteran larvae, caterpillar, diamondback moth and beet armyworm. It has a strong ovicidal activity, being safe to non-target organisms. Tebfenozide has no irritating effect on the eyes and skin without any teratogenic, carcinogenic and mutagenic effects on higher animals, being of high safety to mammals, birds and natural enemies. It is an ideal insecticide during integrated control.
| [Chemical Properties]
Pure white powder, melting point 191 ℃. Slightly soluble in water and organic solvents; stable to light. It is stable at 5 ° C in pH 7 aqueous solution upon light emission.
| [Toxicity (to higher animals)]
Low toxicity | [Mechanism of Action]
Tebufenozide is a pro-skinning compound that selectively controls lepidopteran larvae by acting in close association with the descorticophilin receptor protein. During its effect, tebufenozide mimics the action of natural insect pest hormone 20-hydroxy-descorticoid, leading to its premature, deadly peeling.
| [Control object and using method]
It can be used to control a variety of lettuce larvae such as cabbage, apples and other crops. It is effective in the treatment of all instar larvae at drug interval of 14d.
- Control Spodoptera exigua, Spodoptera litura, Spodoptera frugiperda, melon field borer and cabbage budworm; apply in the early larvae emergence, spray 1 500 ~ 2 000 times 20% SC.
- Control apple leaf roller and peach moth worm, Spray 1000 ~ 2000 times 20% suspension.
- Control corn borer and bean curl moth; spray 1000 ~ 2000 times 20% suspension.
| [Attention]
- This product is toxic to silkworms, should pay attention to be away from the silkworm area.
- This product is generally effective against Plutella xylostella and can be mixed with avermectin.
- Spray uniformly; ensure that the contact of liquid with parasites.
- It is best to apply pesticide in the evening when controlling beet armyworm.
|
| Hazard Information | Back Directory | [Uses]
Synthetic nonsteroidal ecdysone agonist causing premature molting; novel insect growth regulator specific to lepidopteran species. Insecticide. | [Uses]
Tebufenozide is used to control lepidopterous larvae on rice, fruit,
row crops, nut crops, vegetables and vines and in forestry. | [Definition]
ChEBI: A carbohydrazide that is hydrazine in which the amino hydrogens have been replaced by tert-butyl, 3,5-dimethylbenzoyl and 4-ethylbenzoyl groups respectively. It is an insecticide used widely against caterpillars. | [Hazard]
Low toxicity by ingestion, inhalation, and
skin contact. | [Agricultural Uses]
Insecticide, Insect growth regulator: Tebufenozide is an insect growth regulator that interferes
with molting of Lepidopteran larvae. It is used on
fruitworm, fireworms, false armyworm, gypsy moth, and
spanworms, and is applied pre-harvest. Registered for use
in EU countries. Registered for use in the U.S. | [Trade name]
CONFIRM®; MIMIC®; RH-5992® | [Metabolic pathway]
Oxidation of ethyl and methyl substituents of the phenyl rings of
tebufenozide occurs in soils and plants, to give carboxylic acids, alcohols
and a ketone. | [storage]
Store at -20°C | [Degradation]
Tebufenozide was stable at 94 °C for 7 days, stable to light in pH 7
aqueous solution (25 °C) and stable in dark sterile water for 30 days
(25 °C). The DT50 in natural pond water, in light, was 30 days (25 °C)
(PM). It was stable in acidic and neutral buffer solutions. Hydrolysis
was marked in alkaline conditions (DT50 203 days, pH 10, 20°C).
Tebufenozide was stable in sterilised stream water in the dark but
degraded in non-sterile water (DT50 181 days). The insecticide was
photodegraded by sunlight (DT50 83 hours, summer 46°N). The
results suggest that microbial degradation and photolysis will be the
main routes of tebufenozide dissipation in natural aquatic conditions
(Sundaram, 1994). |
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