| Identification | More | [Name]
(S)-(-)-3-BENZYLOXY-1,2-PROPANEDIOL | [CAS]
17325-85-8 | [Synonyms]
1-BENZYL-SN-GLYCEROL
1-O-BENZYL-SN-GLYCEROL
(S)-(-)-1-BENZYLGLYCEROL
(S)-(-)-3-BENZYLOXY-1,2-PROPANEDIOL
(S)-3-BENZYLOXY-1,2-PROPANEDIOL
(S)-GLYCEROL 1-BENZYL ETHER
(S)-(-)-GLYCEROL ALPHA-BENZYL ETHER
(S)-(-)-Benzylglycerol
(S)-(-)-1-BENZYLGLYCEROL 98%
(S)-Glycerol 1-benzyl ether, 1-Benzyl-sn-glycerol | [Molecular Formula]
C10H14O3 | [MDL Number]
MFCD00077914 | [Molecular Weight]
182.22 | [MOL File]
17325-85-8.mol |
| Chemical Properties | Back Directory | [Appearance]
white to slightly yellow crystalline low melting | [Melting point ]
24-26 °C(lit.) | [alpha ]
-5.5o (C=20% IN CHLOROFORM) | [Boiling point ]
261 °C(lit.) | [density ]
1.0966 (rough estimate) | [refractive index ]
-5.5 ° (C=20, CHCl3) | [Fp ]
>230 °F
| [storage temp. ]
2-8°C
| [form ]
powder to lump to clear liquid | [pka]
13.65±0.20(Predicted) | [color ]
White or Colorless to Light yellow | [optical activity]
[α]20/D 5.5±0.5°, c = 20% in chloroform | [BRN ]
2415534 | [CAS DataBase Reference]
17325-85-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [F ]
3-10 | [HS Code ]
2905399590 |
| Hazard Information | Back Directory | [Chemical Properties]
white to slightly yellow crystalline low melting | [Uses]
(S)-(-)-3-Benzyloxy-1,2-propanediol is a useful building block. It is used in the preparation of the nucleotide analog (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cystosine with antiviral activities. It is also used to synthesize cationic cardiolipin analogs with drug delivery systems such as transfection reagents. | [Purification Methods]
Purify the diol by repeated fractional distillation. [Baer et al. J Biol Chem 230 447 1958, Gigg & Gigg J Chem Soc C 1865 1967, Beilstein 6 IV 2247.] |
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