| Identification | More | [Name]
1,10-Phenanthroline hydrate | [CAS]
5144-89-8 | [Synonyms]
1,10-PHENANTHROLINE
1,10-PHENANTHROLINE H2O
1,10-PHENANTHROLINE HYDRATE
1,10-PHENANTHROLINE MONOHYDRATE
1,10-PHENANTHROLINE MONOHYDRATE (O-)
O-PHENANTHROLINE
O-PHENANTHROLINE HYDRATE
O-PHENANTHROLINE MONOHYDRATE
ORTHO-PHENANTHROLINE
ORTHOPHENANTHROLINE MONOHYDRATE
PHENYLANTHROLINE HYDRATE 1,10-
1,10-phenanthrollne,monohydrate
4,5-Phenanthrolinemonohydrate
1,10-PHENANTHROLINE MONOHYDRATE, 99+%
1 10-PHENANTHROLINE MONOHYDRATE 99% &
1,10-PHENANTHROLINE MONOHYDRATE*ACS REAG ENT
1,10-PHENANTHROLINE MONOHYDRATE, 99%, A. C.S. REAGENT
1,10-Phenanthroline(Monohydrate)Gr
1,10-PhenanthrolineGrMonohydrate-RedoxIndicator
1,10-PhenanthrolineGrMonohydrate | [EINECS(EC#)]
200-629-2 | [Molecular Formula]
C12H10N2O | [MDL Number]
MFCD00149973 | [Molecular Weight]
198.22 | [MOL File]
5144-89-8.mol |
| Chemical Properties | Back Directory | [Appearance]
white crystals or powder | [Melting point ]
100-104 °C(lit.)
| [density ]
1.10 | [vapor density ]
6.2 (vs air)
| [storage temp. ]
Store at RT. | [solubility ]
methanol: soluble200MM (Stock solution is stable for months at –20° C.) | [form ]
Needle-Like Crystals | [color ]
Off-white, may become cream-colored during storage | [Stability:]
Stable. Incompatible with iron, other heavy metals, strong oxidizing agents, strong acids. | [Water Solubility ]
<0.01 g/100 mL at 21 ºC | [Merck ]
14,7214 | [BRN ]
4008096 | [CAS DataBase Reference]
5144-89-8(CAS DataBase Reference) | [EPA Substance Registry System]
5144-89-8(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T,N | [Risk Statements ]
R25:Toxic if swallowed.
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S60:This material and/or its container must be disposed of as hazardous waste .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
UN 2811 6.1/PG 3
| [WGK Germany ]
3
| [RTECS ]
SF8437000
| [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29339990 | [Toxicity]
LD50 orally in Rabbit: 132 mg/kg |
| Hazard Information | Back Directory | [General Description]
White crystalline powder or solid. Slight odor. | [Reactivity Profile]
O-PHENANTHROLINE MONOHYDRATE(5144-89-8) is incompatible with strong oxidizers. O-PHENANTHROLINE MONOHYDRATE(5144-89-8) is also incompatible with strong acids. O-PHENANTHROLINE MONOHYDRATE(5144-89-8) forms complex compounds with ferrous ions. . | [Air & Water Reactions]
Insoluble in water. | [Fire Hazard]
Flash point data for this chemical are not available. O-PHENANTHROLINE MONOHYDRATE is probably combustible. | [Chemical Properties]
white crystals or powder | [Uses]
When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions. | [Biochem/physiol Actions]
Metalloprotease inhibitor; chelates iron, zinc and other divalent metals. Effective concentration 1-10 mM. | [Purification Methods]
Crystallise its picrate (m 191o) from EtOH; then the free base is liberated with aqueous alkali, dried at 78o/8mm over P2O5 and crystallised from pet ether (b 80-100o). [Cumper et al. J Chem Soc 1188 1962.] It can be purified by zone melting. It has also been crystallised from hexane, *benzene/pet ether (b 40-60o) or sodium-dried *benzene, dried and stored over H2SO4. The monohydrate is obtained by crystallisation from aqueous EtOH or ethyl acetate. It has been crystallised from H2O (300 parts) to give the monohydrate m 102-103o which sublimes at 10-3mm [Fielding & LeFevre J Chem Soc 1811 1951.] The anhydrous compound has m 118o (after drying at high vacuum at 80o) and is also obtained by recrystallisation from pet ether or *C6H6 (70 parts) and drying at 78o/8mm. [UV: Badger et al. J Chem Soc 3199 1951.] IthasapKainH2Oof 4.857 (25o) or 5.02 (20o) and 4.27 in 50% aqueous EtOH (20o). [Albert et al. J Chem Soc 2240 1948]. [Beilstein 23 H 227, 23 II 235, 23/8 V 419.] |
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