ChemicalBook--->CAS DataBase List--->57078-98-5

57078-98-5

57078-98-5 Structure

57078-98-5 Structure
IdentificationMore
[Name]

4-MALEIMIDOBUTYRIC ACID
[CAS]

57078-98-5
[Synonyms]

4-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)BUTANOIC ACID
4-(2,5-DIOXO-2,5-DIHYDRO-PYRROL-1-YL)-BUTYRIC ACID
4-MALEIMIDOBUTANOIC ACID
4-MALEIMIDOBUTYRIC ACID
GAMMA-MALEIMIDOBUTYRIC ACID
MALEIMIDOPROPIONIC ACID
MBA
N-(3-CARBOXYPROPYL)MALEIMIDE
N-MALEOYL-4-AMINOBUTYRIC ACID
N-MALEOYL-GABA
RARECHEM AL CD 0913
4-MALEIMIDOBUTANOIC ACID DIHYDRATE
γ-Maleimidobutyric acid, 4-Maleimidobutanoic acid, N-(3-Carboxypropyl)maleimide, N-Maleoyl-4-aminobutyric acid, N-Maleoyl-GABA
[EINECS(EC#)]

611-461-8
[Molecular Formula]

C8H9NO4
[MDL Number]

MFCD00043139
[Molecular Weight]

183.16
[MOL File]

57078-98-5.mol
Chemical PropertiesBack Directory
[Appearance]

White Solid
[Melting point ]

95-98 °C
[Boiling point ]

400.1±28.0 °C(Predicted)
[density ]

1.395±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Very Slightly)
[form ]

Solid
[pka]

4.59±0.10(Predicted)
[color ]

White to Pale Yellow
[Usage]

A short crosslinking reagent.
[BRN ]

1455876
[CAS DataBase Reference]

57078-98-5(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

3
[F ]

10-21
[HS Code ]

29251900
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Ethyl acetate-->PETROLEUM ETHER-->CIS-BUTENEDIOIC ANHYDRIDE-->4-Aminobutyric acid-->Maleimide
Hazard InformationBack Directory
[Description]

4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
[Chemical Properties]

White Solid
Questions and Answers (Q&A)Back Directory
[Uses]

  1. A short crosslinking reagent
  2. Modification reagent for thiol groups in proteins
  3. Maleimide Derivatives
  4. MTS & Sulfhydryl Active Reagents
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

57078-98-5(sigmaaldrich)
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