| Identification | More | [Name]
4-Hexanolide | [CAS]
695-06-7 | [Synonyms]
4-Ethyl-4-hydroxybutanoic acid lactone
4-hexanolide
4-HYDROXYHEXANOIC ACID G-LACTONE
Ethyl butyrolactone
FEMA 2556
GAMMA-CAPROLACTONE
GAMMA-ETHYL-GAMMA-BUTYROLACTONE
GAMMA-HEXALACTONE
GAMMA-HEXANOLACTONE
GAMMA-HEXYL LACTONE
G-CAPROLACTONE
G-HEXALACTONE
HEXALACTONE, GAMMA-
HEXANOLACTONE, GAMMA-
Hexanolide-1,4
4-Ethyl-4-butanolide
4-ethylbutanolide (gamma-hexalactone)
4-Hydroxyhexanoic acid lactone
4-hydroxyhexanoicacidlactone
5-ethyldihydro-2(3h)-furanon | [EINECS(EC#)]
211-778-8 | [Molecular Formula]
C6H10O2 | [MDL Number]
MFCD00005401 | [Molecular Weight]
114.14 | [MOL File]
695-06-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
-18°C | [Boiling point ]
219 °C(lit.) | [density ]
1.023 g/mL at 25 °C(lit.)
| [vapor pressure ]
2.4hPa at 20℃ | [FEMA ]
2556 | [refractive index ]
n20/D 1.439(lit.)
| [Fp ]
209 °F
| [storage temp. ]
Sealed in dry,Room Temperature | [form ]
clear liquid | [color ]
Colorless to Almost colorless | [Specific Gravity]
1.023 | [Odor]
at 10.00 % in dipropylene glycol. herbal coconut sweet coumarin tobacco | [Odor Type]
tonka | [Water Solubility ]
77g/L at 20℃ | [JECFA Number]
223 | [BRN ]
107260 | [LogP]
0.3 at 20℃ | [CAS DataBase Reference]
695-06-7(CAS DataBase Reference) | [NIST Chemistry Reference]
2(3H)-Furanone, 5-ethyldihydro-(695-06-7) | [EPA Substance Registry System]
695-06-7(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
2
| [RTECS ]
LU4220000
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [HS Code ]
29322090 |
| Hazard Information | Back Directory | [Description]
gamma-Hexalactone has a warm, powerful, herbaceous, sweet
odor and a sweet, coumarin-caramel taste. May be prepared by
reduction of sorbic acid using Zn, Sn, or SnCl2 and concentrated
HCL in acetic acid solution at 85°C; from ethylene oxide and
sodio-malonic ester; also from propyl alcohol and methylacrylate
in the presence of di-tert-butyl peroxide. | [Chemical Properties]
4-Hexanolide is clear colorless liquid
| [Chemical Properties]
γ-Hexalactone has a sweet, herbaceous, warm, powerful, odor, with a sweet, coumarin-caramel taste. This compound
is also described to have odor as sweet, creamy, lactonic, tobacco and coumarin-like with green coconut nuances. | [Occurrence]
Reported found in apple juice, apricot, orange juice, guava, raisin, papaya, peach, pineapple, berries, asparagus, peas, potato, tomato, breads, cheeses, butter, milk, chicken fat, cooked beef, cooked pork, beer, cognac, grape wines, cocoa,
tea, filberts, pecans, passion fruit, Japanese plum, beans, mushroom, starfruit, mango, dried fig, prickly pear, licorice, soursop, Cape
gooseberry, nectarines, quince, pawpaw and other sources. | [Uses]
γ-Caprolactone was used as curing agent for diglycidyl ether of bisphenol A with ytterbium triflate as an initiator. | [Uses]
γ-Hexalactone may be used as an analytical standard for the determination of the analyte in wine, fruits, biological samples, meat products, and e-cigarette refill solutions by various chromatography techniques. | [Uses]
4-Hexanolide was used as curing agent for diglycidyl ether of bisphenol A with ytterbium triflate as an initiator.
| [Definition]
4-Hexanolide is a gamma-lactone that is oxolan-2-one substituted by an ethyl group at position 5.
| [Preparation]
By reduction of sorbic acid using Zn, Sn or SnCl2 and concentrated HCl in acetic acid solution at 85°C; from ethylene
oxide and sodio-malonic ester; also from propyl alcohol and methylacrylate in the presence of di-tert-butyl peroxide | [Aroma threshold values]
Detection: 1.6 ppm | [Taste threshold values]
Taste characteristics at 75 ppm: sweet, creamy, vanilla-like with green lactonic powdery nuances | [Synthesis Reference(s)]
Tetrahedron Letters, 28, p. 2111, 1987 DOI: 10.1016/S0040-4039(00)96056-8 | [General Description]
γ-Hexalactone is a volatile flavoring compound largely present in food and beverage products, fruits, vegetables, etc. | [Biochem/physiol Actions]
Taste at 5-10ppm | [storage]
Store at -20°C |
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