1,4:3,6-Dianhydro-D-glucitol
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- CAS-Nr.
- 652-67-5
- Bezeichnung:
- 1,4:3,6-Dianhydro-D-glucitol
- Englisch Name:
- Isosorbide
- Synonyma:
- (3R,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diol;at101;IsMotic;Isosorbide (75% solution, 1 g);ucitoL;isobide;hydronol;Isosorbid;NSC 40725;devicoran
- CBNumber:
- CB1162705
- Summenformel:
- C6H10O4
- Molgewicht:
- 146.14
- MOL-Datei:
- 652-67-5.mol
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1,4:3,6-Dianhydro-D-glucitol Eigenschaften
- Schmelzpunkt:
- 60-63 °C (lit.)
- Siedepunkt:
- 175°C/2mmHg(lit.)
- alpha
- 42 º (c=3, H2O)
- Dichte
- 1.0945 (rough estimate)
- Dampfdruck
- 0.007Pa at 20℃
- Brechungsindex
- 45 ° (C=5, H2O)
- storage temp.
- Inert atmosphere,Room Temperature
- Löslichkeit
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- pka
- 13.17±0.40(Predicted)
- Aggregatzustand
- Crystals, Crystalline Solid or Mass
- Farbe
- Off-white to light yellow or beige
- Optische Aktivität
- [α]20/D +45.2°, c = 3 in H2O
- Wasserlöslichkeit
- Soluble in alcohols, water and ketones.
- Sensitive
- Hygroscopic
- Merck
- 14,5224
- BRN
- 80510
- InChIKey
- KLDXJTOLSGUMSJ-JGWLITMVSA-N
- LogP
- -1.39 at 20℃
- CAS Datenbank
- 652-67-5(CAS DataBase Reference)
- EPA chemische Informationen
- D-Glucitol, 1,4:3,6-dianhydro- (652-67-5)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H227 |
Combustible liquid |
Flammable liquids |
Category 4 |
Warnung |
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P210, P280, P370+P378, P403+P235,P501 |
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| Sicherheit |
| P210 |
Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P370+P378 |
Bei Brand: zum Löschen verwenden. |
| P403+P235 |
An einem gut belüfteten Ort aufbewahren. Kühl halten. |
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1,4:3,6-Dianhydro-D-glucitol Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
off-white to light yellow or beige crystals,
Verwenden
Isosorbide is a reagent widely used to prepare detergents, cleansers, cosmetics, agrochemicals and vasodilators.
Definition
A polyol with a hydroxyl group attached to each of
two cis-oriented saturated furan rings. Intermediate
for pharmaceuticals. Combustible.
Biologische Funktion
emergency treatment of acute angle-closure glaucoma.
It should not be confused with isosorbide dinitrate, an
antianginal drug.
Clinical Use
Isosorbide is basically a bicyclic form of sorbitol that is used orally to cause a reduction in intraocular pressure in glaucoma cases. Although a diuretic effect is noted, its
ophthalmologic properties are its primary value.
1,4:3,6-Dianhydro-D-glucitol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol
D-Iditol, 2,5-anhydro-
Hexitol, 2,5-anhydro-
Octa-1,3,7-trien
Tetrahydrofuran
2,2-DIMETHYL-4-(2-OXIRANYL)TETRAHYDROFURO[3,4-D][1,3]DIOXOLE
Isosorbidmononitrat
1,4:3,6-Dianhydro-D-glucitol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 430)Lieferanten
652-67-5(1,4:3,6-Dianhydro-D-glucitol)Verwandte Suche:
D-Glucitol
Isosorbiddinitrat
Glucose
1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol
Diammoniumcarbonat
1,4:3,6-Dianhydro-D-glucitol-2-nitrat
1,4:3,6-Dianhydro-D-glucitol-2-acetat
Isosorbidmononitrat
1,4-Anhydro-D-glucitol
Isononylalkohol
Isooctadecansure
Isoamylalkohol
Alkohole, C11-14-Iso-, C13-reich
Kalium-2-ethylhexanoat
3-Methyl-2-buten-1-ol
Isovalerylchlorid
3-Methylbutan-1-thiol
Triethoxy(3-isocyanatopropyl)silan
- Dianhydro-D-glucitol 98%
- 1,4:3,6-DIANHYDRO-D-SORBITOL
- 1,4:3,6-DIANHYDROGLUCITOL
- 1,4:3,6-DIANHYDROSORBITOL
- 1,4:3,6-DIANHYDRO-D-GLUCITOL
- D-ISOSORBIDE
- DIANHYDRO-D-GLUCITOL
- DIANHYDRO-D-SORBITOL
- ISOSORBIDE
- (3S,3AR,6R,6AR)-HEXAHYDRO-FURO[3,2-B]FURAN-3,6-DIOL
- 1,4:3,6-dianhydro-d-glucito
- Isosorbide, typically 98%
- 1,4:3,6-Dianhydro-D-sorbitol, D-Isosorbide
- Isosorbide,98%
- Dianhydro-D-glucitol,1,4:3,6-Dianhydro-D-sorbitol, D-Isosorbide
- Isosorbide, 98% 100GR
- 1,4:3,6-Dianhydroglucitol
1,4:3,6-Dianhydrosorbitol
- 1,4,3,6,5-Dianhydrosorbitol
- ISOSONBIDE(1,4:3,6-DIANHYDRO-D-SORHITOL)
- Isosorbid
- D-Glucitol, 1,4:3,6-dianhydro-
- D-Glucitol, 1,4:3,6-dianhydro- (9CI)
- NSC 40725
- 1,4,3,6-DIANHYDRO-D-GLUCITOL D-ISOSORBIDE
- 4:3,6-dianhydro-d-glucito
- d-1,4:3,6-dianhydroglucitol
- devicoran
- hydronol
- isobide
- Isosorbide,typically98%
- Isosorbide Isosorbide
- Isosorbide>
- Isosorbide, 97%, reagent grade
- Dianhydro-D-g
- ucitoL
- Dianhydro-D-gL
- Isosorbide USP/EP/BP
- Isosorbide Impurity 21
- Isosorbide Impurity 22
- IsosorbideQ: What is
Isosorbide Q: What is the CAS Number of
Isosorbide Q: What is the storage condition of
Isosorbide Q: What are the applications of
Isosorbide
- Isosorbide (75% solution, 1 g) (1352008)
- Isosorbide (75% solution, 1 g)
- IsMotic
- (3R,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diol
- at101
- 1,4：3,6-dianhydro-D-[UL-13C6]glucitol
- Isosorbitol
- (3S, 3AR, 6R, 6AR) - Hexahydrogen - [3,2-B] furan-3,6-diol)
- Isosorbide
1,4:3,6-Dianhydro-D-glucitol
- 652-67-5
- 662-67-5
- Carbohydrate Synthesis
- Specialty Synthesis
- Monosaccharides
- Carbohydrates & Derivatives
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
