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FAUC-365

FAUC-365 Struktur
474432-66-1
CAS-Nr.
474432-66-1
Englisch Name:
FAUC-365
Synonyma:
FAUC-365;3-dichloro-;FAUC-365 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2;Benzo[b]thiophene-2-carboxamide, N-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyl]-;FAUC-365 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro- phenyl)-piperazin-1-yl]-butyl}-amide;inhibit,Parkinson's disease,Dopamine Receptor,D3 receptor,FAUC365,Dopamine,Inhibitor,FAUC-365,schizophrenia,SPET,Radioligand,FAUC 365
CBNumber:
CB13067544
Summenformel:
C23H25Cl2N3OS
Molgewicht:
462.4351
MOL-Datei:
474432-66-1.mol
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FAUC-365 Eigenschaften

Siedepunkt:
680.3±55.0 °C(Predicted)
Dichte
1.300±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
Löslichkeit
insoluble in EtOH; insoluble in H2O; ≥5.79 mg/mL in DMSO
Aggregatzustand
A crystalline solid
pka
14.55±0.46(Predicted)

Sicherheit

FAUC-365 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

FAUC-365 is a dopamine D3 receptor antagonist (Ki = 0.5 nM). It is selective for dopamine D3 receptors over dopamine D1, D2L, D2S, and D4 receptors (Kis = 8.8, 3.6, 2.6, and 0.34 μM, respectively) as well as the serotonin (5-HT) receptor subtypes 5-HT1A and 5-HT2 (Kis = 0.36 and 2 μM, respectively). FAUC-365 (1-10 mg/kg) prevents memory impairment in the novel object recognition test in dopamine transporter knockdown (DAT-KD) mice when administered prior to object learning.

FAUC-365 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

FAUC-365 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 29)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32686 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 19892 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6393 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		+86-18341751992 +86-15382112998
 757984502@qq.com China 892 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131980 58
BOC Sciences 16314854226
 info@bocsci.com United States 9926 65
Pharmacodia (Beijing) Co.,Ltd +86-400-851-9921
sales@pharmacodia.com China 2317 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9709 58
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994
 2853530910@QQ.com China 8011 62
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136
 info@SuperLan-chem.com China 9779 58
  • FAUC-365
  • FAUC-365 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro- phenyl)-piperazin-1-yl]-butyl}-amide
  • 3-dichloro-
  • FAUC-365 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2
  • inhibit,Parkinson's disease,Dopamine Receptor,D3 receptor,FAUC365,Dopamine,Inhibitor,FAUC-365,schizophrenia,SPET,Radioligand,FAUC 365
  • Benzo[b]thiophene-2-carboxamide, N-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyl]-
  • 474432-66-1
  • C23H25CI2N3OS
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