Moxifloxacin hydrochloride
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- CAS-Nr.
- 186826-86-8
- Englisch Name:
- Moxifloxacin hydrochloride
- Synonyma:
- MOXIFLOXACIN HCL;Avelox;AVALOX;Moxifloxacin hydrochloride CRS;1-cyclopropyl-6-fluoro-8-methoxy-7-((4aS,7aS)-octahydropyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;ACTIRA;Actura;MoxifL;PROFLOX;BAY-12-8039
- CBNumber:
- CB3191433
- Summenformel:
- C21H25ClFN3O4
- Molgewicht:
- 437.8923032
- MOL-Datei:
- 186826-86-8.mol
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Moxifloxacin hydrochloride Eigenschaften
- Schmelzpunkt:
- Slightly yellow to yellow crystalline powder, mp 324-325°
- alpha
- 25D -256° (c = 0.5 in water)
- Siedepunkt:
- 636℃
- RTECS-Nr.
- VB1983750
- Flammpunkt:
- >110°(230°F)
- storage temp.
- 2-8°C
- Löslichkeit
- H2O: soluble5mg/mL, clear (warmed)
- Aggregatzustand
- powder
- Farbe
- white to beige
- Wasserlöslichkeit
- Sparingly soluble in water. Soluble in DMSO
- BRN
- 8377447
- InChIKey
- IDIIJJHBXUESQI-DFIJPDEKSA-N
- SMILES
- N1(C2CC2)C2=C(C=C(F)C(N3C[C@]4([H])CCCN[C@]4([H])C3)=C2OC)C(=O)C(C(O)=O)=C1.[H]Cl |&1:12,18,r|
- CAS Datenbank
- 186826-86-8(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| WGK Germany |
2 |
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| HazardClass |
IRRITANT |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H412 |
Schädlich für Wasserorganismen, mit langfristiger Wirkung. |
Langfristig (chronisch) gewässergefährdend |
Kategorie 3 |
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P273, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P273 |
Freisetzung in die Umwelt vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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Moxifloxacin hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Moxifioxacin hydrochlodde is one of the two new fluoroquinolonecarboxylic
acid antibiotics introduced in 1999 for the treatment of
respiratory tract infections such as community-acquired pneumonia, acute
exacerbations of bronchitis or acute sinusitis. Moxifloxacin can be synthesized
through a 12 step sequence from the classical 4-quinolone-3-carboxylic acid
template. Some advantages of Moxifloxacin over Ciprofloxacin, another of
Bayer's launched quinolones, have been shown, i.e. an enhanced activity
against Gram-positive bacteria (Streptococcus pneumoniae, Clostndium
pneumoniae), a favorable pharmacokinetic profile (good tissue penetration and
plasma concentrations above MICs) and a lack of phototoxicity (UVA
irradiation).
Chemische Eigenschaften
Light yellow to yellow crystalline powder
Verwenden
Moxifloxacin Hydrochloride is an antibacterial agent that inhibits the activities of Topo II (DNA gyrase) and topoisomerase IV.
Definition
ChEBI: A hydrochloride comprising equimolar amounts of moxifloxacin and hydrogen chloride.
Allgemeine Beschreibung
Moxifloxacin Hydrochloride is an anti-infectious compound that belongs to the class of fluoroquinolone antibiotics. It is a well-known broad-spectrum antibiotic prescription medicine effective against a variety of Gram-positive and Gram-negative bacteria including the anaerobic type. It is an
S,S-isomer with two chiral centers. It works by preventing the activity of various crucial enzymes involved in the replication, transcription, recombination, and repair of deoxyribonucleic acid in the bacteria such as DNA gyrase (topoisomerase II), topoisomerase IV. It finds its application in the treatment of various ocular and respiratory tract infections.
Moxifloxacin hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Moxifloxacin hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 745)Lieferanten
186826-86-8()Verwandte Suche:
- BAY-12-8039
- BAY12-8039 HCl
- Moxifloxacin hydrochloride, >=99%
- 4-dihydroquinoline-3-carboxylic acid hydrochloride
- Moxifloxacin Hydrochloride 1
- (1's,6's)-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
- Moxifloxacin Hydrochloride Tablets
- Moxifloxacin hydrochlorideUSP,
98.0-102.0% (HPLC)
- Actura
- ACTIRA
- PROFLOX
- MOXIFLOXACIN HYDROCHLORIDE
- 1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO- 8-METHOXY-7- [(4AS,7AS)-OCTAHYDRO-6H-PYRROLO[3,4-B]PYRIDIN-6-YL]-4-OXO-3-QUINOLINECARBOXYLIC ACID HYDROCHLORIDE
- 1-CYCLOPROPYL-7-[(S,S)-2,8-DIAZA-BICYCLO[4.3.0]NON-8-YL]-6-FLUORO-8-METHOXY-1,4-DIHYDRO-4-OXO-3-QUINOLINE CARBOXYLIC ACID HYDROCHLORIDE
- MoxifloxacineHCl
- Moxifloxacinehydrochloride
- 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7- [(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-,monohydrochloride
- Moxiflaxacin HCL
- Moxifloxacin Hydrochloride (200 mg)
- 1-Cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-8-Methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
- 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-(octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-, Monohydrochloride, (4aS-cis)-
- 1-Cyclopropyl-6-fluoro-8-Methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
- Moxifloxacin HCl USP
- Moxifloxacin HCl (Monohydrate)
- Moxifloxacin and intermediates
- Moxifloxacin hydrochloride Solution, 1000ppm
- AVELOX; AVALOX
- 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid hydrochloride (1:1)
- Moxifloxacin Hydrochlorideand
- MoxifL
- oxacin hydrochL
- Moxifloxacin：Moxifloxacin HCl
- Moxifloxacin hydrochloride solution in Methanol, 1000μg/mL
- Moxifloxacin Hydrochloride ABCDEFGHJKL
- Moxifloxacin hydrochloride USP/EP/BP
- Moxifloxacin Hyderochlodire
- Moxifioxacin hydrochloride
- Moxifloxacin HCl (BAY12-8039)
- 7-[(4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-6-
yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-di
hydroquinoline-3-carboxylic acid hydrochloride
- moxifloxacin for peak identification(Y0000717)Q: What is
moxifloxacin for peak identification(Y0000717) Q: What is the CAS Number of
moxifloxacin for peak identification(Y0000717)
- Moxifloxacin HydrochlorideQ: What is
Moxifloxacin Hydrochloride Q: What is the CAS Number of
Moxifloxacin Hydrochloride Q: What is the storage condition of
Moxifloxacin Hydrochloride
- Moxifloxacin D4 HydrochlorideQ: What is
Moxifloxacin D4 Hydrochloride Q: What is the CAS Number of
Moxifloxacin D4 Hydrochloride Q: What is the storage condition of
Moxifloxacin D4 Hydrochloride
- Nepafenac (CAS 78281-72-8) and Moxifloxacin hydrochloride (CAS 186826-86-8)
- 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic AcidMonohydrochloride
- AVALOX
- 1-cyclopropyl-6-fluoro-8-methoxy-7-((4aS,7aS)-octahydropyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
- MOXIFLOXACIN HCL
- Avelox
- Moxifloxacin hydrochloride CRS
- Moxifloxacin hydrochlorid
- 2,4-Imidazolidinedione,5-(3-bromophenyl)-11-methyl-
- Moxifloxacin hydrochloride hcl
- Moxifloxacin HCl
1-Cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H- pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3- carboxylic acid hydrochloride
- Moxifloxacin (BAY12-8039) HCl
- 186826-86-8
- 196826-86-8
- 86826-86-8
- C21H25FN3O4Cl
