Phosphoryltribromid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R14:Reagiert heftig mit Wasser.
R34:Verursacht Verätzungen.
R37:Reizt die Atmungsorgane.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S43:Zum Löschen . . . (vom Hersteller anzugeben) verwenden (wenn Wasser die Gefahr erhöht, anfügen: "Kein Wasser verwenden").
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S7/8:Behälter trocken und dicht geschlossen halten.
Chemische Eigenschaften
colorless to grey-brown crystals or fused mass
Verwenden
Phosphorus(V) Oxybromide is a reagent used in the preparation of phosphoryl halide for N-protection of amino acids using group assisted purification (GAP). Phosphorus(V) Oxybromide is a brominating agent.
Allgemeine Beschreibung
A colorless crystalline solid or liquid if heated above 133° F with a pungent odor. Phosphorus oxybromide is commonly heated and shipped in a molten state. Soluble in water, but, decomposed by water to hydrobromic and phosphoric acid with evolution of heat. Reacts with organic materials to cause fire. Evolves highly toxic and corrosive gases when exposed to fire. Corrosive to metals and tissue. Used to make other chemicals.
Reaktivität anzeigen
Phosphorus oxybromide is incompatible with water, strong oxidizing agents, alcohols, bases, including amines. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
Health Hazard
CORROSIVE and/or TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Fire will produce irritating, corrosive and/or toxic gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control or dilution water may cause pollution.
Brandgefahr
EXCEPT FOR ACETIC ANHYDRIDE (UN1715), THAT IS FLAMMABLE, some of these materials may burn, but none ignite readily. May ignite combustibles (wood, paper, oil, clothing, etc.). Substance will react with water (some violently), releasing corrosive and/or toxic gases and runoff. Flammable/toxic gases may accumulate in confined areas (basement, tanks, hopper/tank cars, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water. Substance may be transported in a molten form.
Sicherheitsprofil
Poison by ingestion,
inhalation, and shin contact. A corrosive
irritant to skin, eyes, and mucous
membranes. A corrosive material. Reacts
with steam, water to produce much heat
with toxic fumes. When heated to decomposition it emits very toxic fumes of
Brand POx. See also BROMIDES.
Phosphoryltribromid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2,4-Dibromothiazole
2-BROMO-3-IODO-ISONICOTINIC ACID
2-Bromo-4-nitroimidazole
Pyridazine, 3-bromo- (9CI)
3,3,3-Trifluoropropionic acid
6-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE-4-CARBOXYLIC ACID
3-Amino-2-bromopyridine
Pyrimidine, 4-bromo- (8CI,9CI)
4-BROMO-6-FLUORO-2-(TRIFLUOROMETHYL)QUINOLINE
2-BROMO-PYRIDIN-3-YLAMINE HCL
2-(TRIFLUOROMETHYL)QUINOLINE-4-CARBOXYLIC ACID
2,4,6-TRIBROMOPYRIMIDINE
4-BROMO-PYRAN-2-ONE
4-BROMOQUINOLIN-2(1H)-ONE
N-(2-BROMO-3-PYRIDINYL)ACETAMIDE
5-DIMETHYLAMINO-THIOPHENE-2-CARBALDEHYDE
Thiazole-5-carboxaldehyde
2-Bromoquinoline
5-ACETAMIDO-2-BROMOPYRIDINE
2-BROMO-6-ETHOXYPYRIDINE-4-CARBOXYLIC ACID
2-(TRIFLUOROMETHYL)-5,7-DIMETHYLQUINOLINE-4-CARBOXYLIC ACID
1-(3-METHOXYPROPYL)-PIPERAZINE
METHYL 5-BROMOPYRAZINE-2-CARBOXYLATE
2-Brom-5-nitropyridin
2-Bromo-3-nitropyridine
Thiazole-4-carboxaldehyde
2,4-DIBROMOPYRIMIDINE
6-Brom-1H-purin
5-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE-4-CARBOXYLIC ACID
5-Bromthiophen-2-carbaldehyd
5-Amino-2-bromopyridine
4-bromo-2-(trifluoromethyl)quinoline
6-Fluoro-4-(trifluoromethyl)quinoline-2-carboxylic acid ,97%
2-Bromo-5-nitro-4-picoline
2-TRIFLUOROMETHYLQUINOLINE
6-BROMO-2,4-DIMETHOXYPYRIMIDINE
2-Bromoquinoxaline
2-(TRIFLUOROMETHYL)-5-METHYLQUINOLINE-4-CARBOXYLIC ACID
2-CHLORO(BROMO)PYRIMIDINE
2,6-BIS(TRIFLUOROMETHYL)-4-HYDROXYQUINOLINE
