(S)-7-[[2-O-6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-on
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- CAS-Nr.
- 13241-33-3
- Bezeichnung:
- (S)-7-[[2-O-6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-on
- Englisch Name:
- Neohesperidin
- Synonyma:
- NSC 31048;Neohesperdin;NEOHESPERIDIN;Businessperson;NEOHESPERIDIN (PR);(2S)-Neohesperidin;Citrus Polyphenols;Neohesperidin, 90%+;Hesperidin Impurity 9;Neohesperidin 95% HPLC
- CBNumber:
- CB6291569
- Summenformel:
- C28H34O15
- Molgewicht:
- 610.56
- MOL-Datei:
- 13241-33-3.mol
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(S)-7-[[2-O-6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-on Eigenschaften
- Schmelzpunkt:
- 239-243°C
- Siedepunkt:
- 933.7±65.0 °C(Predicted)
- Dichte
- 1.65±0.1 g/cm3(Predicted)
- Dampfdruck
- 0Pa at 20℃
- storage temp.
- Sealed in dry,2-8°C
- Löslichkeit
- DMSO (Slightly), Pyridine (Slightly)
- pka
- 7.14±0.40(Predicted)
- Farbe
- White to Off-White
- Wasserlöslichkeit
- 3.98mg/L at 20℃
- BRN
- 74945
- InChIKey
- ARGKVCXINMKCAZ-RTFRIYMLSA-N
- LogP
- -0.69 at 20℃
- CAS Datenbank
- 13241-33-3(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| S-Sätze: |
22-24/25 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
DJ2981400 |
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| F |
10-21 |
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| HS Code |
29389090 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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(S)-7-[[2-O-6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-on Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Neohesperidin is a flavonoid found in citrus fruit peel that has diverse biological activities.
In vitro, it inhibits osteoclast differentiation, bone resorption, calcium oscillations, and activation of NF-κB and nuclear factor of activated T cells (NFAT) by receptor activator of NF-κB ligand (RANKL).
In vivo, neohesperidin administration protects ovariectomized mice from bone loss. Neohesperidin acts as a hypolipidemic agent, reducing lipid accumulation in HepG2 cells and reversing hyperlipidemia in a mouse model of diet-induced obesity. In a mouse model of diabetes, neohesperidin increases glucose tolerance and decreases insulin resistance while simultaneously decreasing serum triglycerides and total cholesterol and inhibiting lipid accumulation in livers
in vivo.
Chemische Eigenschaften
White powder, easily soluble in methanol and almost insoluble in ether, derived from trifoliate orange peel, sour orange immature fruit, and various citrus fruits.
Verwenden
Neohesperidin can be used in cosmetic products and as a sweetening agent in food & beverages, an antioxidant flavanone glycoside
Definition
ChEBI: Neohesperidin is a flavanone glycoside that is hesperitin having an 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety attached to the 7-hydroxy group. It has a role as an antineoplastic agent and a plant metabolite. It is a neohesperidoside, a disaccharide derivative, a dihydroxyflavanone, a member of 3'-hydroxyflavanones, a monomethoxyflavanone, a flavanone glycoside and a member of 4'-methoxyflavanones. It is functionally related to a hesperetin.
(S)-7-[[2-O-6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-on Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(S)-7-[[2-O-6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 390)Lieferanten
13241-33-3((S)-7-[[2-O-6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-on)Verwandte Suche:
- HESPERETIN-7-NEOHESPERIDOSIDE
- HESPERETIN-7-O-NEOHESPERIDOSIDE
- Neohesperidin HPLC 96% Min
- (s)-a-d-glucopyranosyl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)
- 4h-1-benzopyran-4-one,2,3-dihydro-7-((2-o-(6-deoxy-alpha-l-mannopyranosyl)-bet
- Neohesperidin≥ 98% (HPLC)
- (S)-7-(((2-O-6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
- (S)-4'-METHOXY-3',5,7-TRIHYDROXYFLAVONE-7-[2-O-(ALPHA-L-RHAMNOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE]
- NEOHESPERIDIN
- NEOHESPERIDIN (PR)
- (S)-7-[[2-O-6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
- Neohesperdin
- (s)-4'-methoxy-3',5,7-trihydroxyflavanone-7-[2-o-(α-l-rhamnopyranosyl)-β-d-glucopyranoside]
- NEOHESPERIDIN WITH HPLC
- rhamnopyranosyl-(1→2)-β-D-glucopyranoside
- Neohesperidin，Hesperetin 7-neohesperidoside
- (2S)-2-(3-Hydroxy-4-methoxyphenyl)-5-hydroxy-7-(2-O-α-L-rhamnopyranosyl-β-D-glucopyranosyloxy)-2,3-dihydro-4H-1-benzopyran-4-one
- (2S)-7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
- (2S)-Neohesperidin
- NSC 31048
- HESPERETIN-7-NEOHESPERIDOSIDE hplc
- Neohesperidin, froM Poncirus trifoliata(L.)Raf.
- 7-[[4,5-dihydroxy-6-(hydroxymethyl)-3-[(3,4,5-trihydroxy-6-methyl-2-oxanyl)oxy]-2-oxanyl]oxy]-5-hydroxy-2-(3-hydroxy-5-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
- Neohesperidin 95% HPLC
- Neohesperidin, 98%, from Poncirus trifoliata (L.) Raf.
- 4H-1-Benzopyran-4-one,7-[[2-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-,(2S)-
- Neohesperidin Standard
- 4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2S)-
- (S)-7-(((2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one
- Hesperidin Impurity 9
- (2S)-7-[2-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyloxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
- Neohesperidin USP/EP/BP
- Businessperson
- (2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one
- Neohesperidin (Hesperetin 7-O-neohesperidoside)
- Neohesperidin, 90%+
- Neohesperidin ((S)-5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(a (1458042)
- (2S)-7-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
- Neohesperidin (6CI, 8CI)
- (2RS)-7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one (neohesperidin)
- Citrus Polyphenols
- 13241-33-3
- C28H34O15
- Natural Dyes
- Disaccharide
- Carbohydrates
- Biochemicals and Reagents
- BioChemical
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Flavanones
- Inhibitors
- CITRIMORE
