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Neohesperidin

CAS No.
13241-33-3
Chemical Name:
Neohesperidin
Synonyms
NSC 31048;Neohesperdin;NEOHESPERIDIN;Businessperson;NEOHESPERIDIN (PR);(2S)-Neohesperidin;Citrus Polyphenols;Neohesperidin, 90%+;Hesperidin Impurity 9;Neohesperidin 95% HPLC
CBNumber:
CB6291569
Molecular Formula:
C28H34O15
Molecular Weight:
610.56
MDL Number:
MFCD16661259
MOL File:
13241-33-3.mol
Last updated:2024-04-24 17:21:45

Neohesperidin Properties

Melting point 239-243°C
Boiling point 933.7±65.0 °C(Predicted)
Density 1.65±0.1 g/cm3(Predicted)
vapor pressure 0Pa at 20℃
storage temp. Sealed in dry,2-8°C
solubility DMSO (Slightly), Pyridine (Slightly)
pka 7.14±0.40(Predicted)
color White to Off-White
Water Solubility 3.98mg/L at 20℃
BRN 74945
InChIKey ARGKVCXINMKCAZ-RTFRIYMLSA-N
LogP -0.69 at 20℃
CAS DataBase Reference 13241-33-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII OA5C88H3L0

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Safety Statements  22-24/25
WGK Germany  3
RTECS  DJ2981400
10-21
HS Code  29389090

Neohesperidin price More Price(53)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR3213 Neohesperidin pharmaceutical secondary standard, certified reference material 13241-33-3 50MG $461 2024-03-01 Buy
Sigma-Aldrich 1458042 Neohesperidin United States Pharmacopeia (USP) Reference Standard 13241-33-3 30mg $371.6 2024-03-01 Buy
Sigma-Aldrich 40927 Neohesperidin analytical standard 13241-33-3 10mg $322 2021-12-16 Buy
TCI Chemical N1121 Neohesperidin >97.0%(HPLC) 13241-33-3 100mg $108 2024-03-01 Buy
Cayman Chemical 23028 Neohesperidin ≥98% 13241-33-3 100mg $73 2024-03-01 Buy
Product number Packaging Price Buy
PHR3213 50MG $461 Buy
1458042 30mg $371.6 Buy
40927 10mg $322 Buy
N1121 100mg $108 Buy
23028 100mg $73 Buy

Neohesperidin Chemical Properties,Uses,Production

Description

Neohesperidin is a flavonoid found in citrus fruit peel that has diverse biological activities. In vitro, it inhibits osteoclast differentiation, bone resorption, calcium oscillations, and activation of NF-κB and nuclear factor of activated T cells (NFAT) by receptor activator of NF-κB ligand (RANKL). In vivo, neohesperidin administration protects ovariectomized mice from bone loss. Neohesperidin acts as a hypolipidemic agent, reducing lipid accumulation in HepG2 cells and reversing hyperlipidemia in a mouse model of diet-induced obesity. In a mouse model of diabetes, neohesperidin increases glucose tolerance and decreases insulin resistance while simultaneously decreasing serum triglycerides and total cholesterol and inhibiting lipid accumulation in livers in vivo.

Chemical Properties

White powder, easily soluble in methanol and almost insoluble in ether, derived from trifoliate orange peel, sour orange immature fruit, and various citrus fruits.

Uses

Neohesperidin exhibits lipid-regulating effects in vivo and in vitro. It is a main flavonoid in citrus byproducts (CBP) which possesses anti-oxidant activity.

Uses

Neohesperidin can be used in cosmetic products and as a sweetening agent in food & beverages, an antioxidant flavanone glycoside

Definition

ChEBI: Neohesperidin is a flavanone glycoside that is hesperitin having an 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety attached to the 7-hydroxy group. It has a role as an antineoplastic agent and a plant metabolite. It is a neohesperidoside, a disaccharide derivative, a dihydroxyflavanone, a member of 3'-hydroxyflavanones, a monomethoxyflavanone, a flavanone glycoside and a member of 4'-methoxyflavanones. It is functionally related to a hesperetin.

Neohesperidin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 390)Suppliers
Supplier Tel Email Country ProdList Advantage
BINBO BIOLOGICAL CO.,LTD
+8618629063126 info@binbobiological.com China 290 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58

View Lastest Price from Neohesperidin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Neohesperidin pictures 2024-04-24 Neohesperidin
13241-33-3
US $0.00 / kg 1kg 98% 1000 kg BINBO BIOLOGICAL CO.,LTD
Neohesperidin pictures 2024-04-23 Neohesperidin
13241-33-3
US $0.00-0.00 / kg 1kg 95%, 98% 1000kg Changsha Staherb Natural Ingredients Co., Ltd.
Neohesperidin pictures 2023-08-02 Neohesperidin
13241-33-3
US $0.00-0.00 / kg 1kg 0.99 50000kg Hebei Kingfiner Technology Development Co. , Ltd.
  • Neohesperidin pictures
  • Neohesperidin
    13241-33-3
  • US $0.00-0.00 / kg
  • 95%, 98%
  • Changsha Staherb Natural Ingredients Co., Ltd.
  • Neohesperidin pictures
  • Neohesperidin
    13241-33-3
  • US $0.00-0.00 / kg
  • 0.99
  • Hebei Kingfiner Technology Development Co. , Ltd.

Neohesperidin Spectrum

HESPERETIN-7-NEOHESPERIDOSIDE HESPERETIN-7-O-NEOHESPERIDOSIDE Neohesperidin HPLC 96% Min (s)-a-d-glucopyranosyl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl) 4h-1-benzopyran-4-one,2,3-dihydro-7-((2-o-(6-deoxy-alpha-l-mannopyranosyl)-bet Neohesperidin≥ 98% (HPLC) (S)-7-(((2-O-6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one (S)-4'-METHOXY-3',5,7-TRIHYDROXYFLAVONE-7-[2-O-(ALPHA-L-RHAMNOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE] NEOHESPERIDIN NEOHESPERIDIN (PR) (S)-7-[[2-O-6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one Neohesperdin (s)-4'-methoxy-3',5,7-trihydroxyflavanone-7-[2-o-(α-l-rhamnopyranosyl)-β-d-glucopyranoside] NEOHESPERIDIN WITH HPLC rhamnopyranosyl-(1→2)-β-D-glucopyranoside Neohesperidin,Hesperetin 7-neohesperidoside (2S)-2-(3-Hydroxy-4-methoxyphenyl)-5-hydroxy-7-(2-O-α-L-rhamnopyranosyl-β-D-glucopyranosyloxy)-2,3-dihydro-4H-1-benzopyran-4-one (2S)-7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one (2S)-Neohesperidin NSC 31048 HESPERETIN-7-NEOHESPERIDOSIDE hplc Neohesperidin, froM Poncirus trifoliata(L.)Raf. 7-[[4,5-dihydroxy-6-(hydroxymethyl)-3-[(3,4,5-trihydroxy-6-methyl-2-oxanyl)oxy]-2-oxanyl]oxy]-5-hydroxy-2-(3-hydroxy-5-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one Neohesperidin 95% HPLC Neohesperidin, 98%, from Poncirus trifoliata (L.) Raf. 4H-1-Benzopyran-4-one,7-[[2-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-,(2S)- Neohesperidin Standard 4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2S)- (S)-7-(((2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one Hesperidin Impurity 9 (2S)-7-[2-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyloxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one Neohesperidin USP/EP/BP Businessperson (2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one Neohesperidin (Hesperetin 7-O-neohesperidoside) Neohesperidin, 90%+ Neohesperidin ((S)-5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(a (1458042) (2S)-7-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one Neohesperidin (6CI, 8CI) (2RS)-7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one (neohesperidin) Citrus Polyphenols 13241-33-3 C28H34O15 Natural Dyes Disaccharide Carbohydrates Biochemicals and Reagents BioChemical chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Flavanones Inhibitors CITRIMORE