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derquantel

derquantel Struktur
187865-22-1
CAS-Nr.
187865-22-1
Englisch Name:
derquantel
Synonyma:
derquantel;Unii-0L0ugk6oox;2-Deoxoparaherquamide;2-DeoxoparaherquaMide, 2-DeoxoparaherquaMide A, 2-DesoxoparaherquaMide A, PF 00520904, PNU 141962;Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizin]-10'-one, 2',3',8'a,9,9',10-hexahydro-1'-hydroxy-1',4,4,8',8',11'-hexamethyl-, (1'R,5'aS,7'R,8'aS,9'aR)-
CBNumber:
CB71518503
Summenformel:
C28H37N3O4
Molgewicht:
479.61
MOL-Datei:
187865-22-1.mol
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derquantel Eigenschaften

Siedepunkt:
641.3±55.0 °C(Predicted)
Dichte
1.34
storage temp. 
Store at -20°C
Löslichkeit
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
Aggregatzustand
A solid
pka
15.18±0.60(Predicted)
JECFA Number
75

Sicherheit

derquantel Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Derquantel is an anthelmintic spiroindole that acts as a nicotinic acetylcholine receptor antagonist, causing flaccid paralysis and expulsion of nematodes. A combination of derquantel and the macrocyclic lactone, abamectin , has been found to have synergistic anthelmintic effects against gastrointestinal nematode parasites in sheep.

Verwenden

Derquantel is a semi-synthetic paraherquamide analogue prepared by removal of the 2-oxo group in a four-step sequence of N-protection, reduction, N-deprotection and a final reduction. Derquantel isa potent nematocide and was the first paraherquamide to be successfully commercialised in combination with avermectin. Derquantel, like other paraherquamides, induces a flaccid paralysis in nematodes thought to be due to inhibition of nicotinic acetylcholine receptors acting as an antagonist of acetylcholine.

derquantel Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

derquantel Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 40)Lieferanten
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TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
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AFINE CHEMICALS LIMITED 		+86-0571-85134551
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GIHI CHEMICALS CO.,LIMITED 		+8618058761490
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Lynnchem 86-(0)29-85992781 17792393971
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Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684
 sales@rrkchem.com China 55954 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11289 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829
sales@mitachieve.com China 8864 58
  • derquantel
  • 2-Deoxoparaherquamide
  • Unii-0L0ugk6oox
  • 2-DeoxoparaherquaMide, 2-DeoxoparaherquaMide A, 2-DesoxoparaherquaMide A, PF 00520904, PNU 141962
  • Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizin]-10'-one, 2',3',8'a,9,9',10-hexahydro-1'-hydroxy-1',4,4,8',8',11'-hexamethyl-, (1'R,5'aS,7'R,8'aS,9'aR)-
  • 187865-22-1
  • C28H37N3O4
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