더쿠텔

더쿠텔
더쿠텔 구조식 이미지
카스 번호:
187865-22-1
한글명:
더쿠텔
동의어(한글):
더쿠텔
상품명:
derquantel
동의어(영문):
derquantel;Unii-0L0ugk6oox;2-Deoxoparaherquamide;2-DeoxoparaherquaMide, 2-DeoxoparaherquaMide A, 2-DesoxoparaherquaMide A, PF 00520904, PNU 141962;Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizin]-10'-one, 2',3',8'a,9,9',10-hexahydro-1'-hydroxy-1',4,4,8',8',11'-hexamethyl-, (1'R,5'aS,7'R,8'aS,9'aR)-
CBNumber:
CB71518503
분자식:
C28H37N3O4
포뮬러 무게:
479.61
MOL 파일:
187865-22-1.mol

더쿠텔 속성

끓는 점
641.3±55.0 °C(Predicted)
밀도
1.34
저장 조건
Store at -20°C
용해도
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
물리적 상태
고체
산도 계수 (pKa)
15.18±0.60(Predicted)
JECFA Number
75

안전

더쿠텔 C화학적 특성, 용도, 생산

개요

Derquantel is an anthelmintic spiroindole that acts as a nicotinic acetylcholine receptor antagonist, causing flaccid paralysis and expulsion of nematodes. A combination of derquantel and the macrocyclic lactone, abamectin , has been found to have synergistic anthelmintic effects against gastrointestinal nematode parasites in sheep.

용도

Derquantel is a semi-synthetic paraherquamide analogue prepared by removal of the 2-oxo group in a four-step sequence of N-protection, reduction, N-deprotection and a final reduction. Derquantel isa potent nematocide and was the first paraherquamide to be successfully commercialised in combination with avermectin. Derquantel, like other paraherquamides, induces a flaccid paralysis in nematodes thought to be due to inhibition of nicotinic acetylcholine receptors acting as an antagonist of acetylcholine.

더쿠텔 준비 용품 및 원자재

원자재

준비 용품


더쿠텔 공급 업체

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