Aluminiumhydroxid Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
GERUCHLOSER WEISSER FESTSTOFF IN VERSCHIEDENEN FORMEN.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK: 1,5 mg/m?(Alveolengängige Fraktion); 4 mg/m?(Einatembare Fraktion) Schwangerschaft: Gruppe D (DFG 2006).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation.
INHALATIONSGEFAHREN
Verdampfen bei 20°C vernachlässigbar; eine belästigende Partikelkonzentration in der Luft kann jedoch schnell erreicht werden.
LECKAGE
Verschüttetes Material in Behältern sammeln. Reste mit viel Wasser wegspülen.
R-Sätze Betriebsanweisung:
R36:Reizt die Augen.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
Aluminum hydroxide, Al(OH)3, also known as aluminum trihydroxide, aluminum trihydrate, aluminum hydrate, hydrated alumina, and hydrated aluminum oxide, is a white to whitish-yellow water-insoluble powder with a specific gravity of 2.42. Aluminum hydroxide is used as a baseforpigments, as a water repellent in textile coatings, and as an antacid in medicine. Aluminum hydroxide is soluble in hydrochloric or sulfuric acids or in sodiumhydroxide.
Verwenden
aluminum hydroxide is an inorganic compound used to make a product less transparent. It is also used by formulators as a humectant, and to soften, smooth, and protect the skin. In addition it helps control product viscosity. often found in facial masks and make-up preparations.
Vorbereitung Methode
Aluminum hydroxide adjuvant is prepared by the precipitation of a
soluble aluminum salt by an alkali hydroxide, or the precipitation of
an alkali aluminate by acid.
Pharmazeutische Anwendungen
Aluminum hydroxide adjuvant is used in parenteral human and
veterinary vaccines.It activates Th2 immune responses, including
IgG and IgE antibody responses. It is also used for the isolation of
certain serum components such as blood clotting factors.
Sicherheitsprofil
Poison by intraperitoneal route. Human systemic effects by ingestion: fever, osteomalacia, and gastrointestinal effects. When coprecipitated with bismuth hydroxide and reduced by H2, it is violently flammable in air. Incompatible with chlorinated rubber.
Sicherheit(Safety)
Aluminum hydroxide adjuvant is intended for use in parenteral
vaccines and is generally regarded as nontoxic. It may cause mild
irritation, dryness, and dermatitis on skin contact. On eye contact,
aluminum hydroxide adjuvant may also cause redness, conjunctivitis,
and short-term mild irritation. Ingestion of large amounts may
cause gastrointestinal irritation with nausea, vomiting, and
constipation. Inhalation of the dried product may cause respiratory
irritation and cough. Type I hypersensitivity reactions following
parenteral administration have been reported.
Lager
Aluminum hydroxide adjuvant is stable for at least 2 years when
stored at 4–308℃ in well-sealed inert containers. It must not be
allowed to freeze as the hydrated colloid structure will be
irreversibly damaged.
Inkompatibilitäten
When exposed to phosphate, carbonate, sulfate, or borate anions,
the point of zero charge for aluminum hydroxide adjuvant
decreases.
Regulatory Status
GRAS listed. Accepted for use in human and veterinary parenteral
vaccines in Europe and the USA. The limits for use in human
vaccines are 0.85 mg aluminum/dose (FDA) and 1.25 mg aluminum/
dose (WHO). There are no established limits for use in
veterinary vaccines. Reported in the EPA TSCA Inventory.
Aluminiumhydroxid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
OH-18 hydrotreating catalyst for reforming feedstocks
hydrofining catalyst CH-17
catalyst for selective hydrogenation of C^{3^} fractions
Aluminiumnitrat
Natriumaluminiumfluorid
sodium aluminium acid phosphate for food
methanation catalysts
Aluminium nitrate nonahydrate
Trinatrium-3-hydroxy-4-(4'-sulfonatonaphthylazo)naphthalin-2,7-disulfonat
Silicic acid, aluminum potassium sodium salt
Trinatrium-1-(1-naphthylazo)-2-hydroxynaphthalin-4',6,8-trisulfonat
Aluminiumbromid
ALUMINUM OXIDE,ACTIVATED,NEUTRAL,FOR COLUMN CHROMATOGRAPHY,63-200ΜM
Aluminium, 4,5-Dihydro-5-oxo-1-(4-sulfophenyl)-4-[(4-sulfophenyl)azo]-1H-pyrazol-3-carbonsure Komplex
Erythrosine aluminium lake
Aluminiumorthophosphat
Oxidase, Xanthin-
Aluminium sulfate octadecahydrate
new red
Kaliumtetrafluoroaluminat
Aluminiumtris(dihydrogenphosphat)
COBALT BLUE
Kallikrein
Aluminium ammonium sulfate dodecahydrate
Aluminium, 2-(1,3-Dihydro-3-oxo-5-sulfo-2H-indol-2-yliden)-2,3-dihydro-3-oxo-1H-indol-5-sulfonsure Komplex
Fast Pink lake
Aluminiumfluorid
ALBUMIN, BOVINE
reforming catalysts(series)
sodium aluminium phosphate,basic,for food
carboxyl type cation exchange resin
hydrocracking catalyst 3824 for middle oil
Aluminiumchlorid, basisch
Aluminium, 6-Hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalinsulfonsure Komplex
low temperature CO shift catalysts
CuO-Al inorganic adhesive
Aluminium sulfate hydrate
Trinatriumhexafluoraluminat
dewatering desiccants
hydrofining catalysts (RN series)
