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(S)-Modafinil

CAS No.
112111-47-4
Chemical Name:
(S)-Modafinil
Synonyms
CRL 40983;(S)-Modafinil;(S)-(+)-Modafinil;Modafinil S-Isomer;ArModafinil IMpurity H;YFGHCGITMMYXAQ-IBGZPJMESA-N;Tolterodine Impurity 24-d14;Armodafinil Impurity H (S-Modafinil);2-[(S)-(Diphenylmethyl)sulfinyl]acetamide;AcetaMide, 2-[(S)- (diphenylMethyl)sulfinyl]-
CBNumber:
CB01175404
Molecular Formula:
C15H15NO2S
Molecular Weight:
273.35
MDL Number:
MOL File:
112111-47-4.mol
Last updated:2023-06-08 09:03:02

(S)-Modafinil Properties

Melting point 157-159°C
Boiling point 559.1±50.0 °C(Predicted)
Density 1.283±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMF: 25 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 0.25 mg/ml
form A crystalline solid
pka 14.88±0.40(Predicted)
CAS DataBase Reference 112111-47-4
FDA UNII 152JRG3T0U

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
NFPA 704
0
2 0

(S)-Modafinil Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Used for treatment of excessive sleepiness, α1-adrenoceptor agonist.

Uses

(S)-Modafinil is Used for treatment of excessive sleepiness, it is a1-adrenoceptor agonist.

Definition

ChEBI: (S)-modafinil is a 2-[(diphenylmethyl)sulfinyl]acetamide that has S configuration at the sulfur atom. The racemate comprising (S)-modafinil and its enantiomer, armodafinil, is known as modafinil and is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The enantiomers have similar pharmacological actions in animals. It has a role as a central nervous system stimulant and a eugeroic. It is an enantiomer of an armodafinil.

(S)-Modafinil Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-(+)-Modafinil (S)-Modafinil 2-[(S)-(Diphenylmethyl)sulfinyl]acetamide CRL 40983 AcetaMide, 2-[(S)- (diphenylMethyl)sulfinyl]- Acetamide,2-[(S)-(diphenylmethyl)sulfinyl]- (Related Reference) YFGHCGITMMYXAQ-IBGZPJMESA-N Modafinil S-Isomer S-ModafinilQ: What is S-Modafinil Q: What is the CAS Number of S-Modafinil Q: What is the storage condition of S-Modafinil Q: What are the applications of S-Modafinil ArModafinil IMpurity H Armodafinil Impurity H (S-Modafinil) Tolterodine Impurity 24-d14 Modafinil S-enantiomer CIV (INTERNATIONAL COLD CHAIN SHIPMENT REQUIRED) (30 mg) ((S)-2-(Benzhydrylsulfinyl)acetamide) 112111-47-4 Chiral Reagents Intermediates & Fine Chemicals Neurochemicals Pharmaceuticals