Tegaserod
- CAS No.
- 145158-71-0
- Chemical Name:
- Tegaserod
- Synonyms
- TEGASEROD;Tegaserode;Tegaserod USP/EP/BP;2-[(5-methoxy-1h-indol-3-yl)methylene]-n-pentylhydrazine-carboximidamide;Hydrazinecarboximidamide, 2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pentyl-;(E)-2-((5-methoxy-1H-indol-3-yl)methylene)-N-pentylhydrazine-1-carboximidamide;Tegaserod D10Q: What is Tegaserod D10 Q: What is the CAS Number of Tegaserod D10;Tegaserod 13CD3Q: What is Tegaserod 13CD3 Q: What is the CAS Number of Tegaserod 13CD3;Tegaserod D11 (Major-D10)Q: What is Tegaserod D11 (Major-D10) Q: What is the CAS Number of Tegaserod D11 (Major-D10)
- CBNumber:
- CB0225423
- Molecular Formula:
- C16H23N5O
- Molecular Weight:
- 301.39
- MDL Number:
- MFCD06660144
- MOL File:
- 145158-71-0.mol
Melting point | 155° |
---|---|
Boiling point | 470.6±48.0 °C(Predicted) |
Density | 1.18 |
storage temp. | 2-8°C |
pka | 15.81±0.30(Predicted) |
CAS DataBase Reference | 145158-71-0(CAS DataBase Reference) |
FDA UNII | 458VC51857 |
ATC code | A06AX06 |
SAFETY
Risk and Safety Statements
Hazard Codes | Xi |
---|---|
Risk Statements | 20/21/22-36/37/38 |
Safety Statements | 36/37-36-26 |
Tegaserod price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | T145035 | Tegaserod | 145158-71-0 | 100mg | $550 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0000846 | TEGASEROD 95.00% | 145158-71-0 | 1G | $2355.15 | 2021-12-16 | Buy |
AvaChem | 2786B | Tegaserod | 145158-71-0 | 1g | $649 | 2021-12-16 | Buy |
Alichem | 145158710 | 2-((5-Methoxy-1H-indol-3-yl)methylene)-N-pentylhydrazinecarboximidamide | 145158-71-0 | 1g | $998.4 | 2021-12-16 | Buy |
Chemenu | CM147994 | (E)-2-((5-methoxy-1H-indol-3-yl)methylene)-N-pentylhydrazine-1-carboximidamide 95% | 145158-71-0 | 1g | $1118 | 2021-12-16 | Buy |
Tegaserod Chemical Properties,Uses,Production
Uses
Treatment of gastrointestinal motility disorders (selective serotonin 5HT4antagonist).
Definition
ChEBI: Tegaserod is a member of guanidines, a carboxamidine, a member of hydrazines and a member of indoles. It has a role as a serotonergic agonist and a gastrointestinal drug.
Indications
Tegaserod (Zelnorm) is serotonin-4 (5-HT4) receptor agonists that stimulate GI motility.
brand name
Zelmac (Novartis).
Clinical Use
Tegaserod is being developed as a treatment for constipation- predominant irritable bowel syndrome (IBS). Within the first week, patients treated with tegaserod had significant improvements in abdominal pain and discomfort, constipation, and overall well-being. Efficacy was maintained throughout the treatment period. Tegaserod also demonstrated significant improvements in the three bowel-related assessments (stool frequency, stool consistency, and straining) within the first week, and these improvements were sustained throughout the treatment period. The most common adverse events reported thus far are headache and diarrhea.
Tegaserod Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 | 1056@dideu.com | China | 3581 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9271 | 58 |
AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 992 | 58 |
changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9821 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25363 | 58 |
View Lastest Price from Tegaserod manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-08-12 | Tegaserod
145158-71-0
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | ||
2021-07-20 | Tegaserod
145158-71-0
|
US $1.00-1.00 / KG | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd | ||
2019-07-06 | Tegaserod
145158-71-0
|
US $7.00 / kg | 1kg | 99% | 100KG | Career Henan Chemical Co |