ChemicalBook >> CAS DataBase List >>Curcumol
Curcumol
- CAS No.
- 4871-97-0
- Chemical Name:
- Curcumol
- Synonyms
- Curcumo;CURCUMOL;Curcumae;(-)-Curcumol;Curcumol USP/EP/BP;5,8-Epoxy-10(14)-guaien-8-ol;(3S,3aS,5S,6R,8aS)-5-Isopropyl-3-methyl-8-methyleneoctahydro-6H-3a,6-epoxyazulen-6-ol;(3S,3aS,5S,6R,8aS)-Octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6H-3a,6-epoxyazulen-6-ol;6H-3a,6-Epoxyazulen-6-ol, octahydro-3-methyl-8-methylene-5-(1-methylethyl)-, (3S,3aS,5S,6R,8aS)-;(3s-(3a,3aa,5a,6a,8ab))-octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6h-3a,6-epoxyazulen-6-ol
- CBNumber:
- CB0701727
- Molecular Formula:
- C15H24O2
- Molecular Weight:
- 236.35
- MDL Number:
- MFCD00272163
- MOL File:
- 4871-97-0.mol
- MSDS File:
- SDS
Last updated:2023-05-25 18:00:57
| Melting point | 141.0 to 145.0 °C |
|---|---|
| Boiling point | 334.5±42.0 °C(Predicted) |
| Density | 1.06±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility |
DMSO:55.67(Max Conc. mg/mL);235.54(Max Conc. mM) DMF:20.0(Max Conc. mg/mL);84.62(Max Conc. mM) Ethanol:28.5(Max Conc. mg/mL);120.58(Max Conc. mM) |
| pka | 13.02±0.60(Predicted) |
| color | White to Light yellow |
| InChIKey | QRMPRVXWPCLVNI-YYFQZIEXSA-N |
| LogP | 3.276 (est) |
| CAS DataBase Reference | 4871-97-0 |
| FDA UNII | 9190RTN07X |
Curcumol price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 36236 | ( ?)-Curcumol analytical standard | 4871-97-0 | 10mg | $269 | 2022-05-15 | Buy |
| TCI Chemical | C3439 | Curcumol >98.0%(GC) | 4871-97-0 | 10mg | $133 | 2024-03-01 | Buy |
| TCI Chemical | C3439 | Curcumol >98.0%(GC) | 4871-97-0 | 50mg | $401 | 2024-03-01 | Buy |
| Cayman Chemical | 26849 | Curcumol | 4871-97-0 | 50mg | $596 | 2024-03-01 | Buy |
| Cayman Chemical | 26849 | Curcumol | 4871-97-0 | 100mg | $954 | 2024-03-01 | Buy |
Curcumol Chemical Properties,Uses,Production
Definition
ChEBI: Curcumol is a sesquiterpenoid.
Biological Activity
Curcumol is a biologically active sesquiterpene with many pharmacological activities such as anticancer, antimicrobial, antifungal, antiviral and anti-inflammatory. It efficiently induces apoptosis in many cancer cells by targeting key signaling pathways such as MAPK/ERK, PI3K/Akt and NF-κB, which are often dysregulated in several cancers.
in vitro
Curcumol ((-)-Curcumol) is the major component extracted from root of Rhizoma Curcumae . Curcumol exerts anticancer effect in cholangiocarcinoma cells via down-regulating CDKL3. It induces cell cycle arrest in colon cancer cells via reactive oxygen species and Akt/ GSK3β/cyclin D1 pathway. It suppresses breast cancer cell metastasis by inhibiting MMP-9 via JNK1/2 and Akt-dependent NF-κB signaling pathways.
Curcumol Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 239)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253 | jancyzheng@gcgreenpure.com | China | 952 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
View Lastest Price from Curcumol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-24 | Curcumol
4871-97-0
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2023-02-13 | Curcumol
4871-97-0
|
US $110.00 / kg | 1kg | 99% | 100MT | Hebei baicao biology science and technology co., ltd | |
 |
2022-10-18 | Curcumol
4871-97-0
|
US $1.00 / kg | 1kg | 99% | 5000 Ton | Hebei Duling International Trade Co. LTD |
6H-3a,6-Epoxyazulen-6-ol, octahydro-3-methyl-8-methylene-5-(1-methylethyl)-, (3S,3aS,5S,6R,8aS)-
(3S,3aS,5S,6R,8aS)-Octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6H-3a,6-epoxyazulen-6-ol
CURCUMOL
(3s-(3a,3aa,5a,6a,8ab))-octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6h-3a,6-epoxyazulen-6-ol
5,8-Epoxy-10(14)-guaien-8-ol
(3S-(3alpha,3Aalpha,5alpha,6alpha,8abeta))-octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6H-3A,6-epoxyazulen-6-ol
Curcumae
Curcumol USP/EP/BP
Curcumo
(-)-Curcumol
(3S,3aS,5S,6R,8aS)-5-Isopropyl-3-methyl-8-methyleneoctahydro-6H-3a,6-epoxyazulen-6-ol
4871-97-0
chemical reagent
Inhibitors
pharmaceutical intermediate
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract
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