5-Bromoisatin
- CAS No.
- 87-48-9
- Chemical Name:
- 5-Bromoisatin
- Synonyms
- 5-BROMOINDOLINE-2,3-DIONE;BromoIsatin;5-bromisatin;5-BROMO-3-CHLORO-2-METHYLPYRIDINE;NSC 4980;AKOS B028934;5-BROMOISATIN;5-bromo-isati;AKOS BBS-00000997;BUTTPARK 50\07-94
- CBNumber:
- CB1142138
- Molecular Formula:
- C8H4BrNO2
- Molecular Weight:
- 226.03
- MDL Number:
- MFCD00005719
- MOL File:
- 87-48-9.mol
- MSDS File:
- SDS
Melting point | 247-252 °C (lit.) |
---|---|
Density | 1.7498 (rough estimate) |
refractive index | 1.6120 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Soluble in N,N dimethylformamide. |
pka | 8.74±0.20(Predicted) |
form | Crystalline Powder |
color | Orange |
BRN | 383760 |
InChIKey | MBVCESWADCIXJN-UHFFFAOYSA-N |
CAS DataBase Reference | 87-48-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 37/38-41 | |||||||||
Safety Statements | 26-36/39-37/39-36 | |||||||||
RIDADR | 2811 | |||||||||
WGK Germany | 2 | |||||||||
RTECS | NL7875000 | |||||||||
Hazard Note | Irritant | |||||||||
HS Code | 29337900 | |||||||||
NFPA 704 |
|
5-Bromoisatin price More Price(31)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 476994 | 5-Bromoisatin technical grade, 90% | 87-48-9 | 5g | $17.82 | 2024-03-01 | Buy |
Sigma-Aldrich | 476994 | 5-Bromoisatin technical grade, 90% | 87-48-9 | 25g | $106 | 2024-03-01 | Buy |
TCI Chemical | B1566 | 5-Bromoisatin >97.0%(HPLC)(T) | 87-48-9 | 25g | $143 | 2024-03-01 | Buy |
TCI Chemical | B1566 | 5-Bromoisatin >97.0%(HPLC)(T) | 87-48-9 | 250g | $714 | 2024-03-01 | Buy |
Alfa Aesar | A13641 | 5-Bromoisatin, 90+% | 87-48-9 | 50g | $67.65 | 2024-03-01 | Buy |
5-Bromoisatin Chemical Properties,Uses,Production
Chemical Properties
Orange crystalline powder
Uses
5-Bromoisatin is used in the synthesis of N-derivatives of 5-bromoisatin, N-substituted pyrroles, linear polyaryleneoxindoles, 5-bromodioxindole, cinchoninic acid derivatives, 3-hydroxyoxindole, S-benzyldithiocarbazate Schiff Bases, 5-bromooxindole and Morita-Baylis-Hillman adducts of isatin derivatives. It is an indole derivative.
Definition
ChEBI: 5-Bromoisatin is a member of indoles. It has a role as an anticoronaviral agent.
Synthesis Reference(s)
Tetrahedron Letters, 25, p. 3099, 1984 DOI: 10.1016/0040-4039(84)80017-9
General Description
5-Bromoisatin is a 5-haloisatin. One of the methods reported for its synthesis is by reacting N-halosaccharins with isatin in the presence of SiO2. Its inotropic activity has been studied on rhythmically stimulated papillary muscles of guinea pigs. It is reported to exhibit analgesic and sedative properties at a dose of 0.2g/kg in mice.
Purification Methods
5-Bromoisatin forms red prisms or needles from EtOH. The N-acetate crystallises as yellow prisms from *C6H6, m 170-172o, and the N-methyl derivative forms orange-red needles from MeOH, m 172-173o. [Heller Chem Ber 53 1545 1920, Buu-Hoi Recl Trav Chim, Pays-Bas 73 197 1954, Baker etal. Tetrahedron Lett 215 1978, Beilstein 21 H 453, 21 III/IV 5009.]
5-Bromoisatin Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18629 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21667 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
View Lastest Price from 5-Bromoisatin manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2022-02-19 | 5-Bromoisatin
87-48-9
|
US $0.00 / KG | 1KG | 98.9% | 100 tons | Honest Joy Holdings Limited
|
||
2021-08-12 | 5-Bromoisatin
87-48-9
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | ||
2019-07-06 | 5-Bromoisatin
87-48-9
|
US $1.00 / KG | 1KG | 98% | 1kg,5kg,100kg | Career Henan Chemical Co |
- 5-Bromoisatin
87-48-9
- US $0.00 / KG
- 98.9%
- Honest Joy Holdings Limited
- 5-Bromoisatin
87-48-9
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
- 5-Bromoisatin
87-48-9
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
87-48-9(5-Bromoisatin)Related Search:
1of4