1-Amino-4-methylpiperazine
- CAS No.
- 6928-85-4
- Chemical Name:
- 1-Amino-4-methylpiperazine
- Synonyms
- AMPRZ;1A4MP;1-Amino-4-Methyl;TIMTEC-BB SBB004299;AMINOMETHYLPIPERAZINE;LABOTEST-BB LT00005082;1-piperazinylmethanamine;1-METHYL-4-AMINOPIERAZINE;1-AMINO-4-METHYLPIERAZINE;4-Methyl-1-piperazinamine
- CBNumber:
- CB1177970
- Molecular Formula:
- C5H13N3
- Molecular Weight:
- 115.18
- MDL Number:
- MFCD00006154
- MOL File:
- 6928-85-4.mol
- MSDS File:
- SDS
| Boiling point | 172-175 °C (lit.) |
|---|---|
| Density | 0.957 g/mL at 25 °C (lit.) |
| vapor pressure | 1.29hPa at 25℃ |
| refractive index | 1.4835-1.4855 |
| Flash point | 62 °C |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | water: soluble |
| form | Viscous Solution |
| pka | 7?+-.0.42(Predicted) |
| color | Clear |
| Water Solubility | miscible |
| Sensitive | Air & Light Sensitive |
| BRN | 103334 |
| InChIKey | RJWLLQWLBMJCFD-UHFFFAOYSA-N |
| LogP | -1.61 at 25℃ |
| CAS DataBase Reference | 6928-85-4(CAS DataBase Reference) |
| FDA UNII | J5GBT1LFT2 |
| NIST Chemistry Reference | 1-Amino-4-methylpiperazine(6928-85-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| RIDADR | 2733 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29335995 | |||||||||
| NFPA 704 |
|
1-Amino-4-methylpiperazine price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 255688 | 1-Amino-4-methylpiperazine 97% | 6928-85-4 | 25g | $64.6 | 2024-03-01 | Buy |
| TCI Chemical | A1192 | 1-Amino-4-methylpiperazine >98.0%(GC)(T) | 6928-85-4 | 25mL | $77 | 2024-03-01 | Buy |
| TCI Chemical | A1192 | 1-Amino-4-methylpiperazine >98.0%(GC)(T) | 6928-85-4 | 500mL | $1141 | 2024-03-01 | Buy |
| Alfa Aesar | L19108 | 1-Amino-4-methylpiperazine, 98% | 6928-85-4 | 25g | $46.65 | 2024-03-01 | Buy |
| Alfa Aesar | L19108 | 1-Amino-4-methylpiperazine, 98% | 6928-85-4 | 100g | $126.65 | 2024-03-01 | Buy |
1-Amino-4-methylpiperazine Chemical Properties,Uses,Production
Chemical Properties
clear colorless to light yellow liquid
Uses
1-Amino-4-methylpiperazine has been used:
in synthesis of pyrazolo-pyrazine, -pyridine derivatives and 2-[(4-methylpiperazin-1-yl)iminomethyl]phenol
as a solvating and stabilizing agent in the preparation of uniform Ag nanoparticles (<10nm)
synthesis of N-(4-Fluorobenzylidene)-4-methylpiperazin1-amine
synthesis of 4-Methyl-N-(3,4,5-trimethoxybenzylidene) piperazin-1-amine
synthesis of N-(3,4-Dichlorobenzylidene)-4- methylpiperazin-1-amine
synthesis of N-(4-(Diethylamino)benzylidene)-4- methylpiperazin-1-amine
synthesis of N-(2,5-Dimethoxybenzylidene)-4- methylpiperazin-1-amine
synthesis of 4-Methyl-N-((5-nitrofuran-2- yl)methylene)piperazin-1-amine
Preparation
1-Amino-4-methylpiperazine is obtained from piperazine hexahydrate through the steps of methylation, hydrolysis, nitrosation and reduction.
1-Amino-4-methylpiperazine is synthesized by chlorination of methyl(diethanol)amine (I) and subsequent cyclization of the di(chloroethyl)amine (II) obtained in aqueous hydrazine.
Application
1-Amino-4-methylpiperazine, a derivative of piperazine, is used widely as an intermediate in the synthesis of pharmaceutical agents. It is an important intermediate for Rifampicin. Rifampicin , known as rifampin, is an antibiotic used to treat a several kinds of bacterial infections such as tuberculosis, leprosy and Legionnare's disease.
Flammability and Explosibility
Not classified
1-Amino-4-methylpiperazine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 16801 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | info@edengenechem.com | China | 2169 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| Shenzhen Excellent Biotech Co., Ltd. | 13480692018 | ramyan@ex-biotech.com | CHINA | 954 | 58 |
View Lastest Price from 1-Amino-4-methylpiperazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-29 | 4-Methyl-1-piperazinamine
6928-85-4
|
US $10.00-3.00 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-07-27 | 1-Amino-4-methylpiperazine
6928-85-4
|
US $1.50 / g | 1g | 99.0% Min | 100 Tons | Shaanxi Didu New Materials Co. Ltd | |
 |
2022-09-30 | 1-Amino-4-methylpiperazine
6928-85-4
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 4-Methyl-1-piperazinamine
6928-85-4
- US $10.00-3.00 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 1-Amino-4-methylpiperazine
6928-85-4
- US $1.50 / g
- 99.0% Min
- Shaanxi Didu New Materials Co. Ltd
-
- 1-Amino-4-methylpiperazine
6928-85-4
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.