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L-Histidine hydrochloride monohydrate

L-Histidine hydrochloride monohydrate Structure
L-Histidine hydrochloride monohydrate structure
CAS No.
5934-29-2
Chemical Name:
L-Histidine hydrochloride monohydrate
Synonyms
15N3, 98%);L-HIS HCL H2O;Histidine (H);HISTIDINE HCL;L-His.H2o.HCl;H-His-OH¤HCl¤H;L-HISTIDINEHCL;H-HIS-OH HCL H2O;L-His-OH·HCl·H2O;HISTIDINE HCL H2O
CBNumber:
CB1369616
Molecular Formula:
C6H12ClN3O3
Molecular Weight:
209.63
MDL Number:
MFCD00151027
MOL File:
5934-29-2.mol
MSDS File:
SDS
Last updated:2024-04-07 18:44:46
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L-Histidine hydrochloride monohydrate Properties

Melting point 254 °C (dec.)(lit.)
alpha 9.9 º (c=11, 6 N HCl)
Density 1.49 g/cm3
vapor pressure <1 hPa (20 °C)
storage temp. Store below +30°C.
solubility H2O: 100 mg/mL
form Solid
color White
PH 3.5-4.5 (100g/l, H2O, 20℃)
Odor odorless
PH Range 3 - 4 at 105 g/l at 25 °C
optical activity [α]20/D +9.5±0.5°, c = 5% in 5 M HCl
Water Solubility 169.9 g/L (20 ºC)
Merck 14,4720
BRN 4168261
InChIKey CMXXUDSWGMGYLZ-XRIGFGBMSA-N
LogP -3.32 at 25℃
CAS DataBase Reference 5934-29-2(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII X573657P6P

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  22-24/25-36/37-26
WGK Germany  3
RTECS  MS3119000
F  10
TSCA  Yes
HS Code  29332990
NFPA 704
0
1 0

L-Histidine hydrochloride monohydrate price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H5659 L-Histidine monohydrochloride monohydrate from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0% 5934-29-2 25G $52.3 2024-03-01 Buy
Sigma-Aldrich H5659 L-Histidine monohydrochloride monohydrate from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0% 5934-29-2 100G $134 2024-03-01 Buy
Sigma-Aldrich H5659 L-Histidine monohydrochloride monohydrate from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0% 5934-29-2 1KG $819 2024-03-01 Buy
Sigma-Aldrich 8.16005 (S)-(+)-Histidine hydrochloride monohydrate for synthesis 5934-29-2 25g $38.1 2024-03-01 Buy
Sigma-Aldrich 53370 L-Histidine monohydrochloride monohydrate ≥99.0% (AT) 5934-29-2 25g $32.2 2024-03-01 Buy
Product number Packaging Price Buy
H5659 25G $52.3 Buy
H5659 100G $134 Buy
H5659 1KG $819 Buy
8.16005 25g $38.1 Buy
53370 25g $32.2 Buy

L-Histidine hydrochloride monohydrate Chemical Properties,Uses,Production

Chemical Properties

white crystals or cryst. or granular powder

Uses

L-Histidine Hydrochloride Monohydrate can be used as AhR activators to treat gluten-induced gastrointestinal diseases. It can also be used for hair coloring method.

Uses

L-Histidine is used in cell culture media formulations used in biomanufacturing. L-Histidine has been used to study cultures of the human T-lymphoblastic leukemia cell line MOLT-4 to study modulation of apoptosis.

Uses

L-Histidine monohydrochloride, non-animal, is used in cell culture media formulations used in biomanufacturing. The use of non-animal-sourced L-Histidine and other components avoids the risk of contaminating bioproducts with adventitious viruses.

General Description

Chemicals play an important role in the stabilization of a biologic drug during its manufacturing and formulation process – for instance, by preventing aggregation. We offer a wide range of high-quality stabilizers, buffers and salts to successfully purify and formulate your biomolecules. Specifically developed for high-risk applications, they are low in bioburden and endotoxins.
As part of our Emprove? Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC? portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Biochem/physiol Actions

L-Histidine is biosynthesized from ATP, 5-phosphoribosyl-1-pyrophosphate (PRPP), and glutamine. This essential amino acid can be degraded to glutamate by histidiase, urocanase and imidazolonepropionase; it is also the precursor of histamine by action of histidine decarboxylase.

Purification Methods

Crystallise the monohydrochloride from aqueous EtOH or 60% aqueous EtOH (m 259odec). Alternatively dissolve 10g in 50mL of H2O, decolourise with Norite, filter, evaporate it in a vacuum to a syrup, cool to room temperature, add 95% EtOH with stirring until slightly turbid, scratch the sides of the vessel until crystals form, then add slowly 40mL of EtOH and keep at 0o overnight, filter the solid off, wash it several times with EtOH and dry it in a vacuum. [Cox J Biol Chem 78 475 1929, Cox et al. J Biol Chem 81 73 1929, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 1972, 2098 1961, Beilstein 25 II 407, 25 III/IV 4346.]

L-Histidine hydrochloride monohydrate synthesis

71-00-1
5934-29-2
Synthesis of L-Histidine hydrochloride monohydrate from L-Histidine

L-Histidine hydrochloride monohydrate Preparation Products And Raw materials

Raw materials

HEMOGLOBIN Soy bean Isoflavone Isoflavone 10-40% L-Lysine Hydrolyzate Ion exchange resin column

Preparation Products

N-Boc-L-Histidine

L-Histidine hydrochloride monohydrate Suppliers

Global( 472)Suppliers
Supplier Tel Email Country ProdList Advantage
airuikechemical co., ltd. 		+undefined86-15315557071 sales02@airuikechemical.com China 994 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Xiamen AmoyChem Co., Ltd 		+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Shandong chuangyingchemical Co., Ltd. 		18853181302 sale@chuangyingchem.com CHINA 5909 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49390 58
Supplier Advantage
airuikechemical co., ltd. 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
Xiamen AmoyChem Co., Ltd 		58
Hubei xin bonus chemical co. LTD 		58
Shandong chuangyingchemical Co., Ltd. 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58

View Lastest Price from L-Histidine hydrochloride monohydrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
l-histidine hydrochloride monohydrate pictures 2024-04-07 l-histidine hydrochloride monohydrate
5934-29-2
 US $0.00-0.00 / Kg 1Kg 99.9% 200tons airuikechemical co., ltd.
L-Histidine hydrochloride monohydrate pictures 2023-08-02 L-Histidine hydrochloride monohydrate
5934-29-2
 US $0.00-0.00 / kg 1kg 0.99 500000kg Hebei Kingfiner Technology Development Co. , Ltd.
L-Histidine hydrochloride monohydrate pictures 2022-02-25 L-Histidine hydrochloride monohydrate
5934-29-2
 US $3.99 / KG 1KG 99% 100KG Hong Kong Tiansheng New Material Trading Co., Ltd

L-Histidine hydrochloride monohydrate Spectrum

L-Histidine hydrochloride monohydrate(5934-29-2)FT-IRL-Histidine hydrochloride monohydrate(5934-29-2)IRL-Histidine hydrochloride monohydrate(5934-29-2)Raman

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L-ALPHA-AMINO-4(OR 5)-IMIDAZOLEPROPIONIC ACID MONOHYDROCHLORIDE, MONOHYDRATE L-ALPHA-AMINO-BETA-(4-IMIDAZOLYL)PROPIONIC ACID MONOHYDROCHLORIDE L-HIS HCL H2O L-HISTIDINE MONOHYDROCHLORIDE H2O L-(+)-HISTIDINE HYDROCHLORIDE MONOHYDRATE L-HISTIDINE HYDROCHLORIDE MONOHYDRATE L-HISTIDINE MONOHYDROCHLORIDE MONOHYDRATE L-HISTIDINE HCL H2O L-HISTIDINE HCL MONOHYDRATE L-HISTINE HYDROCHLORIDE MONOHYDRATE L-HISTINE HCL MONOHYDRATE H-HIS-OH HCL H2O (S)-(+)-HISTIDINE MONOHYDROCHLORIDE MONOHYDRATE Histidinehydrochloridemonohydrate l-histidinehcl,histidinehcl L-Histidinehydrochloride,mono L-Histidinehydrochloridehydrate monohydrochloride,monohydrate,l-histidin monohydrochloride,monohydrate,L-Histidine L-Histidine-d3 HCl H2O (S)-(+)-HISTIDINE HYDROCHLORIDE MONOHYDR Histidine (H) Histidine Solution (H) GUANIDINE:HCL (13C, 99% 15N3, 98%) L-HISTIDINE:HCL:H2O (D5, 98% Histidine (H) Solution, 100ppm L-Histidine monohydrochloride monohydrate Vetec(TM) reagent grade, 99% PHENOL/CHLOROFORM/IAA 1 PHASE BIOTECH GR L-HISTIDINE:HCL:H2O (<5% D) (13C6) H-His-OH.HCl monohydrate H-His-OH¤HCl¤H L-His-OH·HCl·H2O L-Histidine hydrochloride monohydrate98.5-101.0% (Titration: anhydrous basis) L-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride L-Histidine Hydrochloride Monohydrate H-His-OH.HCl (S)-(+)-Histidine hydrochloride monohydrate for synthesis L(+)-Histidine monohydrochloride-1-hydrate HISTIDINE HCL H2O L-HistidineMonohydrochlorideForBiochemistry HISTIDINE HCL l-α-amino-β-(4-imidazolyl)propionic acid monohydrochloride L-HISTIDINEMONOHYDROCHLORIDE,MONOHYDRATE,FCC L-HISTIDINEHCL Histidine Hydrochloride, L-, 1-Hydrate L-(+)-Histidine hydrochloride monohydrate, 98+% L-HISTIDINE HYDROCHLORIDE extrapure CHR L-Histidine monohydrate monohydrochloride L-Histidine HCL Mono (2S)-2-Amino-3-(3H-imidazol-4-yl)propanoic acid hydrate hydrochloride L-Histidine hydrochl L-HISTIDINE:HCL:H20 L-HISTIDINE:HCL:H2O (<5% D) L-Histidine hydrochloride Monohydrate, 98% 100GR L-Histidine hydrochloride Monohydrate, 98% 25GR (S)-2-AMino-3-(1H-iMidazol-4-yl)propanoic acid hydrochloride hydrate L-Histidine monohydrochloride monohydrate ,99% (S)-(+)-Histidine hydrochloride monohydrate L-Histidine monohydrochloride monohydrat