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Alizapride

CAS No.
59338-93-1
Chemical Name:
Alizapride
Synonyms
MS-5080;Litican;Plitican;Nausilen;Vergentan;ALIZAPRIDE;Alizapride CAS NO.59338-93-1;VergentanQ: What is Vergentan Q: What is the CAS Number of Vergentan;n-(1-allyl-2-pyrrolidinylmethyl)-6-methoxy-1h-benzotriazole-5-carboxamide;N-[(1-allylpyrrolidin-2-yl)methyl]-6-methoxy-2H-benzotriazole-5-carboxamide
CBNumber:
CB2162373
Molecular Formula:
C16H21N5O2
Molecular Weight:
315.37
MDL Number:
MFCD00867757
MOL File:
59338-93-1.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:40

Alizapride Properties

Melting point 139°
Boiling point 580.3±40.0 °C(Predicted)
Density 1.224±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
pka 7.09±0.40(Predicted)
CAS DataBase Reference 59338-93-1(CAS DataBase Reference)
FDA UNII P55703ZRZY
ATC code A03FA05

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P280
Toxicity LD50 i.v. in mice (5 days): 92.7 mg/kg (Bulteau)

Alizapride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0001412 ALIZAPRIDE 95.00% 59338-93-1 1G $780.15 2021-12-16 Buy
American Custom Chemicals Corporation API0001412 ALIZAPRIDE 95.00% 59338-93-1 1KG $7294.7 2021-12-16 Buy
Chemenu CM123074 N-((1-allylpyrrolidin-2-yl)methyl)-6-methoxy-1H-benzo[d][1,2,3]triazole-5-carboxamide 95% 59338-93-1 1g $327 2021-12-16 Buy
Crysdot CD31001364 Alizapride 95+% 59338-93-1 1g $620 2021-12-16 Buy
AHH MT-46749 Alizapride 98% 59338-93-1 10g $780 2021-12-16 Buy
Product number Packaging Price Buy
API0001412 1G $780.15 Buy
API0001412 1KG $7294.7 Buy
CM123074 1g $327 Buy
CD31001364 1g $620 Buy
MT-46749 10g $780 Buy

Alizapride Chemical Properties,Uses,Production

Originator

Plitican ,Delagrange ,France ,1981

Definition

ChEBI: 6-methoxy-N-[(1-prop-2-enyl-2-pyrrolidinyl)methyl]-2H-benzotriazole-5-carboxamide is a member of benzotriazoles.

Manufacturing Process

38.6 g (0.2 mol) of 2-methoxy-4,5-azimidobenzoic acid were dissolved in anhydrous toluene and 56 g (0.4 mol) of 1-allyl-2-amino-methylpyrrolidine were added. The mixture was heated to 50°C and then 42 g (0.3 mol) of phosphoric anhydride were added. The mixture was warmed at reflux temperature for 3 hours and then cooled to 80°C. After adding water, the aqueous layer was alkalized. The crystals were filtered, washed with water and then dissolved in 450 ml of acetone. After crystallization, the product was 40.4 g (yield 65%) of N-(1'-allyl-2'-pyrrolidylmethyl)-2-methoxy-4,5- azimidobenzamide having a melting point of 139°C were obtained.

Therapeutic Function

Neuroleptic, Antiemetic

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ALIZAPRIDE n-(1-allyl-2-pyrrolidinylmethyl)-6-methoxy-1h-benzotriazole-5-carboxamide 1h-benzotriazole-5-carboxamide,6-methoxy-n-((1-(2-propenyl)-2-pyrrolidinyl)met 6-methoxy-n-((1-(2-propenyl)-2-pyrrolidinyl)methyl)-1h-benzotriazole-5-carbo Nausilen Plitican Vergentan 6-Methoxy-N-{[1-(2-propnyl)-2-pyrrolidinyl]methyl]-1H-benzotriazole-5-carboxamide Litican 6-Methoxy-N-[[1-(2-propenyl)-2-pyrrolidinyl]methyl]-1H-benzotriazole-5-carboxamide MS-5080 6-methoxy-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5-carboxamide N-[(1-allylpyrrolidin-2-yl)methyl]-6-methoxy-2H-benzotriazole-5-carboxamide 1H-Benzotriazole-5-carboxaMide,6-Methoxy-N-[[1-(2-propen-1-yl)-2-pyrrolidinyl]Methyl]- N-((1-Allylpyrrolidin-2-yl)Methyl)-6-Methoxy-1H-benzo[d][1,2,3]triazole-5-carboxaMide VergentanQ: What is Vergentan Q: What is the CAS Number of Vergentan Alizapride CAS NO.59338-93-1 59338-93-1 89338-87-3 C16H21N5O2