4-Cholesten-3-one
- CAS No.
- 601-57-0
- Chemical Name:
- 4-Cholesten-3-one
- Synonyms
- CHOLESTENONE;4-Cholestenone;4-CHOLESTEN-3-ONE;3-Oxocholest-4-ene;3-OXO-4-CHOLESTENE;cholest-4-en-3-one;4-Cholestene-3-one;CHOLEST-4-ENE-3-ONE;3-KETO-4-CHOLESTENE;(+)-4-CHOLESTEN-3-ONE
- CBNumber:
- CB3222827
- Molecular Formula:
- C27H44O
- Molecular Weight:
- 384.64
- MDL Number:
- MFCD00003663
- MOL File:
- 601-57-0.mol
- MSDS File:
- SDS
Melting point | 79-82 °C |
---|---|
alpha | 92.5 º (c=2, CHCl3) |
Boiling point | 451.27°C (rough estimate) |
Density | 0.9717 (rough estimate) |
refractive index | 1.5100 (estimate) |
storage temp. | -20°C |
solubility | Chloroform (Sparingly), Methanol (Slightly, Heated) |
form | Solid |
color | White to Off-White |
optical activity | [α]23/D +91.0°, c = 2 in chloroform |
Water Solubility | <0.5 g/L |
BRN | 4707774 |
Stability | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 601-57-0(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | 7T94NHD99C |
NIST Chemistry Reference | Cholest-4-en-3-one(601-57-0) |
EPA Substance Registry System | Cholest-4-en-3-one (601-57-0) |
SAFETY
Risk and Safety Statements
Hazard statements | H413 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 22-24/25-36-26 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | FZ7700000 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29142900 | |||||||||
NFPA 704 |
|
4-Cholesten-3-one price More Price(30)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 188174 | (+)-4-Cholesten-3-one 98% | 601-57-0 | 1g | $33 | 2024-03-01 | Buy |
Sigma-Aldrich | 188174 | (+)-4-Cholesten-3-one 98% | 601-57-0 | 10g | $313 | 2024-03-01 | Buy |
Alfa Aesar | A11743 | 4-Cholesten-3-one, 98+% | 601-57-0 | 5g | $71.65 | 2024-03-01 | Buy |
Alfa Aesar | A11743 | 4-Cholesten-3-one, 98+% | 601-57-0 | 25g | $253.65 | 2024-03-01 | Buy |
Cayman Chemical | 25713 | Cholestenone | 601-57-0 | 5g | $81 | 2024-03-01 | Buy |
4-Cholesten-3-one Chemical Properties,Uses,Production
Description
Cholestanone is a cholesterol metabolite that has a keto group in place of the 3-hydroxy group on cholesterol. It decreases TGF-β-induced Smad2 phosphorylation and TGF-β expression and prevents inhibition of DNA synthesis by TGF-β in Mv1Lu cells when used at a concentration of 50 μg/ml. Increased fecal excretion of cholestenone is correlated with an increased risk of colorectal cancer. Cholestenone reduces serum cholesterol levels in a variety of animal models but is toxic to rats when administered at doses of 700-1,000 mg/kg per day, inducing hypertrophy in and reducing the activity of the adrenal gland. It has been used as synthetic intermediate in the synthesis of steroids.
Chemical Properties
white to light yellow crystals or powder
Uses
4-Cholesten-3-one is used as a chiral building block for proteomics research. It is an intestinal metabolite of cholesterol and exhibits an anti-obesity effect on animals.
Definition
ChEBI: Cholest-4-en-3-one is a cholestanoid that is cholest-4-ene substituted by an oxo group at position 3. It has a role as a human metabolite and a plant metabolite. It is a cholestanoid and a 3-oxo-Delta(4) steroid.
General Description
Cholestenone is a cholesterol metabolite and analog, which substitutes membrane cholesterol and elevates membrane fluidity.
4-Cholesten-3-one Preparation Products And Raw materials
4-Cholesten-3-one Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12446 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5873 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21667 | 55 |
Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 13349 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 7193 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52861 | 58 |
Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |
View Lastest Price from 4-Cholesten-3-one manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-08-15 | 4-Cholesten-3-one
601-57-0
|
US $20.00-1.00 / kg | 1kg | 0.99 | 20 tons | Hebei Yanxi Chemical Co., Ltd. | ||
2023-10-10 | 4-Cholesten-3-one
601-57-0
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | ||
2023-09-06 | 4-Cholesten-3-one
601-57-0
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. |
- 4-Cholesten-3-one
601-57-0
- US $20.00-1.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
- 4-Cholesten-3-one
601-57-0
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
- 4-Cholesten-3-one
601-57-0
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
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