Cefeprime dihydrochloride
- CAS No.
- 107648-80-6
- Chemical Name:
- Cefeprime dihydrochloride
- Synonyms
- CEFEPIME HCL;Cefepime DiHCl;Cefepime Impurity 16;CefepiMe hydrochloric;Cefepime Hydrochlorede;CEFEPIME DIHYDROCHLORIDE;CEFEPRIME DIHYDROCHLORIDE;CEFEPIME HCL STERILE POWDER;Cefepime Hydrochloride/arginine;Cefeprime dihydrochloride USP/EP/BP
- CBNumber:
- CB3739703
- Molecular Formula:
- C19H25ClN6O5S2
- Molecular Weight:
- 553.49
- MDL Number:
- MFCD01766069
- MOL File:
- 107648-80-6.mol
| Melting point | 230 °C (decomp) |
|---|---|
| solubility |
Water:10.0(Max Conc. mg/mL);17.5(Max Conc. mM) DMSO:6.0(Max Conc. mg/mL);10.5(Max Conc. mM) |
| CAS DataBase Reference | 107648-80-6(CAS DataBase Reference) |
| FDA UNII | 2A1O4F5N0C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H314-H317-H334 |
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501-P261-P285-P304+P341-P342+P311-P501 |
Cefeprime dihydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C242765 | CefepimeDihydrochloride | 107648-80-6 | 10mg | $130 | 2021-12-16 | Buy |
| AvaChem | 2437 | Cefepime Dihydrochloride | 107648-80-6 | 5g | $189 | 2021-12-16 | Buy |
| Chemenu | CM126625 | 1-(((6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-methylpyrrolidin-1-iumchloridehydrochloride 97% | 107648-80-6 | 1g | $234 | 2021-12-16 | Buy |
| Crysdot | CD00013211 | Cefepime hydrochloride 97% | 107648-80-6 | 1g | $248 | 2021-12-16 | Buy |
| AvaChem | 2437 | Cefepime Dihydrochloride | 107648-80-6 | 25g | $590 | 2021-12-16 | Buy |
Cefeprime dihydrochloride Chemical Properties,Uses,Production
Description
Cefepime Hydrochloride is the hydrochloride salt of a semi-synthetic, beta-lactamase-resistant, fourth-generation cephalosporin antibiotic derived from an Acremonium fungal species with broad-spectrum bactericidal activity. Administered parenterally, cefepime inhibits bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity, resulting in a reduction of bacterial cell wall stability and cell lysis. This agent is more active against a variety of Gram-positive pathogens compared to third-generation cephalosporins.
Uses
Cefepime hydrochloride has been used as a pharmaceutical reference standard for the determination of analytes in pharmaceutical preparations by spectrophotometric and chromatographic techniques. Cefepime is commonly used in the treatment of severe atypical pneumonia and infections caused by multi-drug resistant microorganisms (e.g. Pseudomonas aeruginosa), and is also indicated for the empirical treatment of febrile neutropenia.
Definition
ChEBI: Cefepime hydrochloride is a hydrochloride that is the monohydrate of the dihydrochloride salt of cefepime. It has a role as an antibacterial drug. It is a hydrochloride, a hydrate and a cephalosporin. It contains a cefepime(1+).
Cefeprime dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
| Cangzhou Wanyou New Material Technology Co.,Ltd | 18631714998 | sales@czwytech.com | CHINA | 906 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 | faith@widelychemical.com | CHINA | 742 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Hebei Runbin Biotechnology Co. LTD | 13180553332 | 2179877681@qq.com | CHINA | 996 | 58 |
View Lastest Price from Cefeprime dihydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-08-16 | Cefepime Dihydrochloride
107648-80-6
|
US $300.00 / KG | 1KG | >99% | 50000kg/Month | Weijer International Trade (Hebei) Co., Ltd | |
 |
2023-03-27 | Cefeprime dihydrochloride
107648-80-6
|
US $25.00 / KG | 1KG | 0.99 | 5000KG/MONTH | XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD | |
 |
2023-03-16 | Cefepime Hydrochloride
107648-80-6
|
US $1.00 / kg | 1kg | 99.6%HPLC | 20tons | Hebei Duling International Trade Co. LTD |
-
- Cefepime Dihydrochloride
107648-80-6
- US $300.00 / KG
- >99%
- Weijer International Trade (Hebei) Co., Ltd
-
- Cefeprime dihydrochloride
107648-80-6
- US $25.00 / KG
- 0.99
- XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD
-
- Cefepime Hydrochloride
107648-80-6
- US $1.00 / kg
- 99.6%HPLC
- Hebei Duling International Trade Co. LTD