6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE
- CAS No.
- 1140-81-4
- Chemical Name:
- 6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE
- Synonyms
- 6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE;6-Acetamido-2-methyl-4-hydroxyquinoline;N-Acetyl-4-hydroxy-2-methyl-6-quinolinamine;N-(2-methyl-4-oxo-1H-quinolin-6-yl)acetamide;N-(4-hydroxy-2-Methylquinolin-6-yl)acetaMide;N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide;Acetamide, N-(4-hydroxy-2-methyl-6-quinolinyl)-;n-(2-Methyl-4-oxo-1,4-dihydroquinolin-6-yl)acetamide
- CBNumber:
- CB41091481
- Molecular Formula:
- C12H12N2O2
- Molecular Weight:
- 216.24
- MDL Number:
- MOL File:
- 1140-81-4.mol
- MSDS File:
- SDS
Last updated:2023-05-24 08:28:53
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P |
6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T323233 | N-(4-HYDROXY-2-METHYL-6-QUINOLINYL)ACETAMIDE AldrichCPR | 1140-81-4 | 5MG | $70.9 | 2024-03-01 | Buy |
| TRC | H114085 | N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide | 1140-81-4 | 1g | $430 | 2021-12-16 | Buy |
| AK Scientific | 9559AJ | 6-Acetamido-4-hydroxy-2-methylquinoline | 1140-81-4 | 250mg | $552 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA152500 | 6-Acetamido-2-methyl-4-hydroxyquinoline | 1140-81-4 | 500mg | $645 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA152500 | 6-Acetamido-2-methyl-4-hydroxyquinoline | 1140-81-4 | 50mg | $107 | 2021-12-16 | Buy |
6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE Chemical Properties,Uses,Production
Uses
N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide is an intermediate in the synthesis of NSC 23766 (N900280), which is a highly soluble and membrane permeable Rac GTPase inhibitor. NSC 23766 inhibits Rac GTPase by targeting Rac activation by guanine nucleotide exchange factor (GEF). NSC 23766 has been shown to inhibit the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells.
Synthesis Reference(s)
Journal of the American Chemical Society, 70, p. 4065, 1948 DOI: 10.1021/ja01192a031
Synthesis of 6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE from (E)-Methyl 3-(4-acetaMidophenyliMino)butanoate
6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 15)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503259 +86-19930503259 | cherry@crovellbio.com | China | 18455 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Shanghai JiYi Biotechnology Co. Ltd. | 13621943973 | sales@shjiyipharmatech.com | China | 1166 | 55 |
| Shanghai Qiao Chemical Science Co., Ltd | 021-58892003 | info@qiaochem.com | China | 5881 | 65 |
| Angel Pharmatech, Ltd. | 17317130613 | 3358272972@qq.com | China | 3237 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 40036 | 58 |
| Carbosynth | -- | sales@carbosynth.com | United Kingdom | 6018 | 58 |
1140-81-4(6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE)Related Search:
6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE
N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide
N-Acetyl-4-hydroxy-2-methyl-6-quinolinamine
N-(4-hydroxy-2-Methylquinolin-6-yl)acetaMide
N-(2-methyl-4-oxo-1H-quinolin-6-yl)acetamide
6-Acetamido-2-methyl-4-hydroxyquinoline
Acetamide, N-(4-hydroxy-2-methyl-6-quinolinyl)-
n-(2-Methyl-4-oxo-1,4-dihydroquinolin-6-yl)acetamide
1140-81-4