CANDESARTAN-D4
- CAS No.
- 1346604-70-3
- Chemical Name:
- CANDESARTAN-D4
- Synonyms
- CV-11974-d4;CANDESARTAN-D4;[2H4]-Candesartan;Candesartan M1-d4;Candesartan D4 (CV-11974 D4);2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1-(phenyl-d4)-1'-phenyl]-4-yl]Methyl]-1H-benziMidazole-7-carboxylic Acid;Candesartan D4Q: What is Candesartan D4 Q: What is the CAS Number of Candesartan D4 Q: What is the storage condition of Candesartan D4
- CBNumber:
- CB4477701
- Molecular Formula:
- C24H16D4N6O3
- Molecular Weight:
- 444.48
- MDL Number:
- MFCD08063415
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H360 |
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
CANDESARTAN-D4 price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25419 | Candesartan-d4 ≥99% deuterated forms (d1-d4) | 1346604-70-3 | 1mg | $335 | 2024-03-01 | Buy |
| Cayman Chemical | 25419 | Candesartan-d4 ≥99% deuterated forms (d1-d4) | 1346604-70-3 | 5mg | $669 | 2024-03-01 | Buy |
| Usbiological | 005550 | Candesartan-d4 | 1346604-70-3 | 1mg | $531 | 2021-12-16 | Buy |
| TRC | C175578 | Candesartan-d4 | 1346604-70-3 | 25mg | $3630 | 2021-12-16 | Buy |
| ChemScene | CS-4129 | CandesartanD4 98.85% | 1346604-70-3 | 1mg | $216 | 2021-12-16 | Buy |
CANDESARTAN-D4 Chemical Properties,Uses,Production
Description
Candesartan-d4 is intended for use as an internal standard for the quantification of candesartan by GC- or LC-MS. Candesartan is an antagonist of the angiotensin II type 1 (AT1) receptor (Kis = 0.17, 0.12, and 0.12 nM for human AT1, rat AT1A, and rat AT1B recombinant receptors, respectively) and an active metabolite of the prodrug candesartan cilexitil (Item No. 10489). It is selective for AT1 over AT2 receptors (Ki = 26,500 nM for the human recombinant AT2 receptor). It inhibits angiotensin II-induced contraction of isolated rabbit aortic strips and increases in blood pressure in rats following intravenous administration (ID50 = 0.033 mg/kg). Formulations containing candesartan have been used in the treatment of hypertension and heart failure.
Chemical Properties
CANDESARTAN-D4 is White to Off-White Solid
Uses
Labelled Candesartan, an angiotensin II type-1 receptor antagonist. Used in treatment of congestive heart failure. Antihypertensive.
Uses
CANDESARTAN-D4 is an angiotensin II type-1 receptor antagonist. Used in treatment of congestive heart failure. Antihypertensive.
CANDESARTAN-D4 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| PureChemland Co.,Ltd. | 19150123681 | 3848291069@qq.com | China | 3249 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| Cato Research Chemicals Inc. | 020-81960175 | min.he@cato-chem.com | China | 1958 | 55 |
| ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 17994 | 56 |