ChemicalBook >> CAS DataBase List >>KHELLIN
KHELLIN
- CAS No.
- 82-02-0
- Chemical Name:
- KHELLIN
- Synonyms
- VISNAGIN;eskel;norkel;KHELIN;keloid;ammivin;KHELLIN;chellin;kelamin;kelicor
- CBNumber:
- CB5269554
- Molecular Formula:
- C14H12O5
- Molecular Weight:
- 260.24
- MDL Number:
- MFCD00005007
- MOL File:
- 82-02-0.mol
Last updated:2023-06-08 17:06:37
| Melting point | 150154°C |
|---|---|
| Boiling point | 180200°C0.05mm Hg |
| Density | 1.1954 (rough estimate) |
| refractive index | 1.4560 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | crystalline |
| color | light yellow |
| Water Solubility | 247.2g/L(25 ºC) |
| Merck | 14,5309 |
| BRN | 263185 |
| LogP | 1.770 (est) |
| NCI Dictionary of Cancer Terms | keloid |
| FDA UNII | 5G117T0TJZ |
| EPA Substance Registry System | Khellin (82-02-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H311+H331-H315-H319-H335 | |||||||||
| Precautionary statements | P280-P301+P310+P330-P302+P352+P312-P304+P340+P311-P305+P351+P338 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25-38-36/37/38-23/24/25 | |||||||||
| Safety Statements | 36/37/39-45-26 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LV1050000 | |||||||||
| HS Code | 2932.99.7000 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| Toxicity | LD50 in mice, rats (mg/kg): 30.6, 34.4 i.v.; 50.8, 68.8 orally (Busch) | |||||||||
| NFPA 704 |
|
KHELLIN price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL89481 | Khellin phyproof? Reference Substance | 82-02-0 | 100MG | $358 | 2024-03-01 | Buy |
| Sigma-Aldrich | 60730 | Khellin for microscopy | 82-02-0 | 10g | $234 | 2024-03-01 | Buy |
| Sigma-Aldrich | 00899 | Khellin analytical standard | 82-02-0 | 100MG | $244 | 2024-03-01 | Buy |
| TCI Chemical | K0039 | Khellin >95.0%(GC) | 82-02-0 | 5g | $155 | 2024-03-01 | Buy |
| TCI Chemical | K0039 | Khellin >95.0%(GC) | 82-02-0 | 25g | $497 | 2024-03-01 | Buy |
KHELLIN Chemical Properties,Uses,Production
Uses
vasodilator (coronary), photosensitizer
Uses
Khellin has been used as a reference standard for supercritical fluid extraction of khellin from Ammi visnaga L. fruits to understand the various medicinal effects of γ-Pyrones by reversed phase HPLC method.
Definition
ChEBI: Khellin is a furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator. It has a role as a vasodilator agent, a bronchodilator agent, an anti-asthmatic agent and a cardiovascular drug. It is an organic heterotricyclic compound, an oxacycle and a furanochromone. It is functionally related to a 5H-furo[3,2-g]chromen-5-one.
brand name
Ammivin (Marion Merrell Dow); Khelloyd (Hoechst-Roussel).
Synthesis Reference(s)
Journal of Medicinal Chemistry, 26, p. 1672, 1983 DOI: 10.1021/jm00366a002
General Description
Khellin, is reported to be an efficient drug for treating vitiligo when combined with ultraviolet A irradiation.
Purification Methods
Crystallise khellin from H2O, MeOH, pet ether or Et2O. The hydrochloride has m 98o(dec) (from EtOH/HCl). [Beilstein 19 II 236, 19 III/IV 2816, 19/6 V 320.]
KHELLIN Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 138)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9271 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29067 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 20000 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
View Lastest Price from KHELLIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-07 | KHELLIN USP/EP/BP
82-02-0
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-05-12 | Khellin
82-02-0
|
US $0.00-0.00 / KG | 1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd |
-
- KHELLIN USP/EP/BP
82-02-0
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- Khellin
82-02-0
- US $0.00-0.00 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
82-02-0(KHELLIN)Related Search:
CHEMBRDG-BB 5160161
4,9-Dimethoxy-7-(2-phenylethenyl)-5H-furo[3,2-g][1]
benzopyran-5-one azaspirium chloride Mecrifurone Timefurone
benzopyran-5-one azaspirium chloride Mecrifurone Timefurone
1of4
4,9-DIMETHOXY-7-METHYL-5H-FURO[3,2-G]-[1]BENZOPYRAN-5-ONE
4,9-DIMETHOXY-7-METHYLFURO[3,2-G](1)BENZOPYRAN-5-ONE
2-g)(1)benzopyran-5-one,4,9-dimethoxy-7-methyl-5h-furo(
4,9-dimethoxy-7-methyl-5-oxo-1,8-dioxabenz-(f)indene
ammispasmin
ammivin
ammivisnagen
norkel
rykellin
simeskellina
vasokellina
viscardan
visnagalin
KHELIN
KHELLIN
5,8-dimethoxy-2-methyl-4’,5’-furo-6,7-chromone
5,8-dimethoxy-2-methyl-6,7-furanochromone
amicardine
amikellin
ammipuran
VISAMMIN
4,9-dimethoxy-7-methylfurano(3,2-g)chromen-5-one
KHELLIN(VISAMMIN)(P)
7-Methyl-4,9-dimethoxy-5H-furo[3,2-g][1]benzopyran-5-one
4,9-dimethoxy-7-methyl-furo[3,2-g]chromen-5-one
4,9-dimethoxy-7-methylfuro[3,2-g]chromen-5-one
4,9-Dimethoxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-one
Visammin
KHELLIN LIGHT YELLOW CRYSTALS
4,9-dimethoxy-7-methyl-5-oxofuro(3,2-g)(1)benzopyran
4,9-dimethoxy-7-methyl-5-oxofuro(3,2-g)-1,2-chromene
5,8-dimethoxy-2-methyl-4’,5’-furano-6,7-chromone
benecardin
cardio-khellin
chellin
chellina
eskel
gynokhellan
kalangin
kelamin
kelicor
kelicorin
kellosal
keloid
khelangin
khelfren
khelisem
khellamine
khellanals
khelloyd
lynamine
medekellin
methafrone
4,9-dimethoxy-7-methyl-5H-furo[3,2-g]chromen-5-one
KHELLIN USP/EP/BP
5H-Furo[3,2-g][1]benzopyran-5-one, 4,9-dimethoxy-7-methyl-
Khellin（Ammispasmin,Ammivin,Ammivisnagen,Benecardin,Benekardin,Cardio-khellin,Corafurone,Coronin,Eskel,Gynok...）
Khellin>
1-nitroso-1-(phenylmethyl)urea