ChemicalBook >> CAS DataBase List >>3-Hydroxy-N-methyl-3-phenyl-propylamine
3-Hydroxy-N-methyl-3-phenyl-propylamine
- CAS No.
- 42142-52-9
- Chemical Name:
- 3-Hydroxy-N-methyl-3-phenyl-propylamine
- Synonyms
- 3-(METHYLAMINO)-1-PHENYLPROPAN-1-OL;3-METHYLAMINO-1-PHENYLPROPANOL;N-METHYL-3-PHENYL-3-HYDROXYPROPYLAMINE;α-[2-(MethyL;Compound PDK0217;Atomoxetine EP Imp H;Atomoxetine USP RC A;Fluoxetine Impurity 1;Fluoxetine EP IMpurity A;Fluoxertine EP impurity A
- CBNumber:
- CB6345561
- Molecular Formula:
- C10H15NO
- Molecular Weight:
- 165.24
- MDL Number:
- MFCD00674078
- MOL File:
- 42142-52-9.mol
- MSDS File:
- SDS
Last updated:2024-04-15 18:41:30
| Melting point | 64 °C |
|---|---|
| Boiling point | 170 °C / 31mmHg |
| Density | 1.017±0.06 g/cm3(Predicted) |
| vapor pressure | 0.037Pa at 25℃ |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Soluble), Methanol (Slightly) |
| pka | 14.24±0.20(Predicted) |
| form | Solid |
| color | Off-White to Pale Yellow |
| InChI | InChI=1S/C10H15NO/c1-11-8-7-10(12)9-5-3-2-4-6-9/h2-6,10-12H,7-8H2,1H3 |
| InChIKey | XXSDCGNHLFVSET-UHFFFAOYSA-N |
| SMILES | C(C1C=CC=CC=1)(O)CCNC |
| LogP | 0.98 |
| CAS DataBase Reference | 42142-52-9(CAS DataBase Reference) |
| FDA UNII | I28ND993BO |
3-Hydroxy-N-methyl-3-phenyl-propylamine price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0002201 | Fluoxetine impurity A CRS, European Pharmacopoeia (EP) Reference Standard | 42142-52-9 | Y0002201 | $156 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHR2840 | Atomoxetine Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material | 42142-52-9 | 25MG | $573 | 2024-03-01 | Buy |
| Sigma-Aldrich | 463477 | α-[2-(Methylamino)ethyl]benzyl alcohol 97% | 42142-52-9 | 1g | $33 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1044470 | Atomoxetine Related Compound A United States Pharmacopeia (USP) Reference Standard | 42142-52-9 | 10mg | $1210 | 2024-03-01 | Buy |
| TCI Chemical | M1960 | alpha-[2-(Methylamino)ethyl]benzyl Alcohol >98.0%(GC)(T) | 42142-52-9 | 5g | $35 | 2024-03-01 | Buy |
3-Hydroxy-N-methyl-3-phenyl-propylamine Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
3-Hydroxy-N-methyl-3-phenyl-propylamine is an aromatic amino alcohol used as an initiator in radical addition reactions with tetrahalomethanes.
Uses
α-[2-(Methylamino)ethyl]benzyl Alcohol (Fluoxetine EP Impurity A(Atomoxetine Related Compound A)) is an aromatic amino alcohol used as an initiator in radical addition reactions with tetrahalomethanes.This compound is found as an impurity in fluoxetine (F597100).
Synthesis
3-Hydroxy-N-methyl-3-phenyl-propylamine is one of important intermediate of preparation fluoxetine Hydrochloride. Up to now, the method for preparing N-methyl-3-phenyl-3-hydroxy-propylamine is mainly divided into three kinds; the first kind of be replace (halogen with 3-, dialkylamine, amido or ethoxycarbonyl) Propiophenone be starting raw material, earlier after reduction, the 1-phenylpropyl alcohol that 3-is replaced is converted into 3-Hydroxy-N-methyl-3-phenyl-propylamine again; Second kind and being: the different azoles alkane of 2-methyl-5-phenyl is carried out reductive ring open makes target compound; The third be: with getting the 1-phenylpropyl alcohol that 3-replaces behind epoxy styrene and the derivative reductive ring open thereof, be translated into target compound earlier.
Synthesis of 3-Hydroxy-N-methyl-3-phenyl-propylamine from 3-METHYLAMINO-1-PHENYLACETONE HYDROCHLORIDE
3-Hydroxy-N-methyl-3-phenyl-propylamine Preparation Products And Raw materials
Raw materials
3-(METHYLAMINO)ACRYLOPHENONE
3-iodo-1-phenylpropan-1-ol
2-Methyl-5-phenylisoxazolidine
1-Propanone, 3-[methyl(phenylmethyl)amino]-1-phenyl-
3-METHYLAMINO-1-PHENYLACETONE HYDROCHLORIDE
1of3
Preparation Products
Global( 401)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +8615383190639 | admin@86-ss.com | China | 1000 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 885 | 50 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21667 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2966 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8820 | 58 |
View Lastest Price from 3-Hydroxy-N-methyl-3-phenyl-propylamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-09-19 | 3-Hydroxy-N-methyl-3-phenyl-propylamine
42142-52-9
|
US $99.00-66.00 / kg | 0.001kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2024-09-19 | 3-Hydroxy-N-methyl-3-phenyl-propylamine
42142-52-9
|
US $5.00 / kg | 1kg | ≥99% | 50mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2024-09-18 | 3-Hydroxy-N-methyl-3-phenyl-propylamine
42142-52-9
|
US $0.00 / Kg/Drum | 1KG | 99%min | 1000KG | WUHAN FORTUNA CHEMICAL CO., LTD |
-
- 3-Hydroxy-N-methyl-3-phenyl-propylamine
42142-52-9
- US $99.00-66.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- 3-Hydroxy-N-methyl-3-phenyl-propylamine
42142-52-9
- US $5.00 / kg
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- 3-Hydroxy-N-methyl-3-phenyl-propylamine
42142-52-9
- US $0.00 / Kg/Drum
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
42142-52-9(3-Hydroxy-N-methyl-3-phenyl-propylamine)Related Search:
ALPHA-(2-METHYLAMINO)-ETHYLBENZENEMETHANOL
ALPHA-[2-(METHYLAMINO)ETHYL]BENZYL ALCOHOL
3-HYDROXY-N-METHYL-3-PHENYLPROPYLAMINE
3-METHYLAMINO-1-PHENYL-1-PROPANOL
N-METHYL-3-HYDROXY-3-PHENYL PROPYLAMINE
(RS)-3-MethylaMino-1-Phenyl-Propan-1-ol
3-Hydroxy-N-Methyl-3-phenyl-propylaMin
alpha-[2-(MethylaMino)ethyl]benzyl alcohol 97%
A-[2-(Methylamino)Ethyl]Benzenemethanol
3-N-methyl-1-phenyl-propanol
BENZENEMETHANOL,A-[2-(METHYLAMINO)ETHYL]
3-methylamino-1-phenylpropano
α-[2-(Methylamino)ethyl]benzenemethanol
N-Methyl-3-Phenyl-3-Hydroxypropylamin
3-Methylamino-1-phenylpropane-1-ol
3-Hydroxy-N-methyl-3-phenyl-pr
α-[2-(methylamino)ethyl]benzyl alcohol
1-PHENYL-3-METHYLAMINO-1-PROPANOL
PHENYL METHYL AMINO PROPANOL
Propanol, 3-methylamino-1-phenyl
Benzenemethanol, α-[2-(methylamino)ethyl]-
Benzenemethanol, alpha-[2-(methylamino)ethyl]-
1-Phenyl-3-(methylamino)propane-1-ol
N-Methyl-3-hydroxy-3-phenyl-1-propanamine
N-Methyl-3-phenyl-3-hydroxypropylamine,97%
N-Methyl 3-phenyl-3-hydroxy-1-propanaMine
N-(3-Hydroxy-3-phenylpropyl)MethylaMine
N-Methyl-N-(3-hydroxy-3-phenylpropyl)aMine
3-Hydroxy-N-methyl-3-phenylpropylamine
3-(Methylamino)-1-phenylpropanol
Fluoxetine EP IMpurity A
Methyl({3-[3-(2-Methylphenoxy)phenyl]propyl})aMine
Fluoxertine EP impurity A -C
(RS)-3-Methylamino-1-phenyl-1-propanol
Fluoxertine EP impurity A
3-(methylamino)-1-phenylpropan-1-ol Oxalate
Fluoxetine Impurity 1(EP-A)
Atomoxetine Impurity 8(Atomoxetine EP Impurity H)
Fluoxetine Hydrochloride Impurity Ⅰ：Fluoxetine EP Impurity A
Fluoxetine Impurity 1
Atomoxetine EP Imp H
3-(Methylamino)-1-Phenyl-1-Ppropanol
α-[2-(Methylamino)ethyl]benzylAlcohol>
Fluoxetine EP Impurity A (Atomoxetine EP Impurity H)
Atomoxetine USP RC A
α-[2-(MethyL
3-Hydroxy-N-methyl-3-phenyl-propylamine USP/EP/BP
Fluoxetine intermediate，3-Hydroxy-N-methyl-3-phenyl- propylamine
Hydroxy-N-methyl-3-phenyl-propylamine
ALPHA-[2-(METHYLAMINO)ETHYL]BENZYL
Atomoxetine EP Impurity H/ Atomoxetine Related Compound A
3-Hydroxy-N-Methyl-3-Phenyl-Propylamine(42142-52-9)
α-[2-(Methylamino)ethyl]benzyl Alcohol
α-[2-(Methylamino)ethyl]benzenemethanol
Fluoxetine Hydrochloride Impurity Ⅰ：Fluoxetine EP Impurity A
(1RS)-3-(Methylamino)-1-phenylpropan-1-ol
Atomoxetine Related Compound A (3-(Methylamino)-1-phenylpropan-1-ol) (1044470)
3-METHYLAMINO-1-PHENYLPROPANOL
3-(METHYLAMINO)-1-PHENYLPROPAN-1-OL