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3-Hydroxy-N-methyl-3-phenyl-propylamine

CAS No.
42142-52-9
Chemical Name:
3-Hydroxy-N-methyl-3-phenyl-propylamine
Synonyms
3-(METHYLAMINO)-1-PHENYLPROPAN-1-OL;3-METHYLAMINO-1-PHENYLPROPANOL;N-METHYL-3-PHENYL-3-HYDROXYPROPYLAMINE;α-[2-(MethyL;Compound PDK0217;Atomoxetine EP Imp H;Atomoxetine USP RC A;Fluoxetine Impurity 1;Fluoxetine EP IMpurity A;Fluoxertine EP impurity A
CBNumber:
CB6345561
Molecular Formula:
C10H15NO
Molecular Weight:
165.24
MDL Number:
MFCD00674078
MOL File:
42142-52-9.mol
MSDS File:
SDS
Last updated:2024-04-15 18:41:30

3-Hydroxy-N-methyl-3-phenyl-propylamine Properties

Melting point 64 °C
Boiling point 170 °C / 31mmHg
Density 1.017±0.06 g/cm3(Predicted)
vapor pressure 0.037Pa at 25℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Soluble), Methanol (Slightly)
pka 14.24±0.20(Predicted)
form Solid
color Off-White to Pale Yellow
InChI InChI=1S/C10H15NO/c1-11-8-7-10(12)9-5-3-2-4-6-9/h2-6,10-12H,7-8H2,1H3
InChIKey XXSDCGNHLFVSET-UHFFFAOYSA-N
SMILES C(C1C=CC=CC=1)(O)CCNC
LogP 0.98
CAS DataBase Reference 42142-52-9(CAS DataBase Reference)
FDA UNII I28ND993BO

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36/37
WGK Germany  3
HS Code  2922199695
NFPA 704
0
2 0

3-Hydroxy-N-methyl-3-phenyl-propylamine price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0002201 Fluoxetine impurity A CRS, European Pharmacopoeia (EP) Reference Standard 42142-52-9 Y0002201 $156 2024-03-01 Buy
Sigma-Aldrich PHR2840 Atomoxetine Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material 42142-52-9 25MG $573 2024-03-01 Buy
Sigma-Aldrich 463477 α-[2-(Methylamino)ethyl]benzyl alcohol 97% 42142-52-9 1g $33 2024-03-01 Buy
Sigma-Aldrich 1044470 Atomoxetine Related Compound A United States Pharmacopeia (USP) Reference Standard 42142-52-9 10mg $1210 2024-03-01 Buy
TCI Chemical M1960 alpha-[2-(Methylamino)ethyl]benzyl Alcohol >98.0%(GC)(T) 42142-52-9 5g $35 2024-03-01 Buy
Product number Packaging Price Buy
Y0002201 Y0002201 $156 Buy
PHR2840 25MG $573 Buy
463477 1g $33 Buy
1044470 10mg $1210 Buy
M1960 5g $35 Buy

3-Hydroxy-N-methyl-3-phenyl-propylamine Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

3-Hydroxy-N-methyl-3-phenyl-propylamine is an aromatic amino alcohol used as an initiator in radical addition reactions with tetrahalomethanes.

Uses

α-[2-(Methylamino)ethyl]benzyl Alcohol (Fluoxetine EP Impurity A(Atomoxetine Related Compound A)) is an aromatic amino alcohol used as an initiator in radical addition reactions with tetrahalomethanes.This compound is found as an impurity in fluoxetine (F597100).

Synthesis

3-Hydroxy-N-methyl-3-phenyl-propylamine is one of important intermediate of preparation fluoxetine Hydrochloride. Up to now, the method for preparing N-methyl-3-phenyl-3-hydroxy-propylamine is mainly divided into three kinds; the first kind of be replace (halogen with 3-, dialkylamine, amido or ethoxycarbonyl) Propiophenone be starting raw material, earlier after reduction, the 1-phenylpropyl alcohol that 3-is replaced is converted into 3-Hydroxy-N-methyl-3-phenyl-propylamine again; Second kind and being: the different azoles alkane of 2-methyl-5-phenyl is carried out reductive ring open makes target compound; The third be: with getting the 1-phenylpropyl alcohol that 3-replaces behind epoxy styrene and the derivative reductive ring open thereof, be translated into target compound earlier.

2538-50-3
42142-52-9
Synthesis of 3-Hydroxy-N-methyl-3-phenyl-propylamine from 3-METHYLAMINO-1-PHENYLACETONE HYDROCHLORIDE
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View Lastest Price from 3-Hydroxy-N-methyl-3-phenyl-propylamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Hydroxy-N-methyl-3-phenyl-propylamine pictures 2024-09-19 3-Hydroxy-N-methyl-3-phenyl-propylamine
42142-52-9
US $99.00-66.00 / kg 0.001kg 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
3-Hydroxy-N-methyl-3-phenyl-propylamine pictures 2024-09-19 3-Hydroxy-N-methyl-3-phenyl-propylamine
42142-52-9
US $5.00 / kg 1kg ≥99% 50mt/year Jinan Finer Chemical Co., Ltd
3-Hydroxy-N-methyl-3-phenyl-propylamine pictures 2024-09-18 3-Hydroxy-N-methyl-3-phenyl-propylamine
42142-52-9
US $0.00 / Kg/Drum 1KG 99%min 1000KG WUHAN FORTUNA CHEMICAL CO., LTD

3-Hydroxy-N-methyl-3-phenyl-propylamine Spectrum

ALPHA-(2-METHYLAMINO)-ETHYLBENZENEMETHANOL ALPHA-[2-(METHYLAMINO)ETHYL]BENZYL ALCOHOL 3-HYDROXY-N-METHYL-3-PHENYLPROPYLAMINE 3-METHYLAMINO-1-PHENYL-1-PROPANOL N-METHYL-3-HYDROXY-3-PHENYL PROPYLAMINE (RS)-3-MethylaMino-1-Phenyl-Propan-1-ol 3-Hydroxy-N-Methyl-3-phenyl-propylaMin alpha-[2-(MethylaMino)ethyl]benzyl alcohol 97% A-[2-(Methylamino)Ethyl]Benzenemethanol 3-N-methyl-1-phenyl-propanol BENZENEMETHANOL,A-[2-(METHYLAMINO)ETHYL] 3-methylamino-1-phenylpropano α-[2-(Methylamino)ethyl]benzenemethanol N-Methyl-3-Phenyl-3-Hydroxypropylamin 3-Methylamino-1-phenylpropane-1-ol 3-Hydroxy-N-methyl-3-phenyl-pr α-[2-(methylamino)ethyl]benzyl alcohol 1-PHENYL-3-METHYLAMINO-1-PROPANOL PHENYL METHYL AMINO PROPANOL Propanol, 3-methylamino-1-phenyl Benzenemethanol, α-[2-(methylamino)ethyl]- Benzenemethanol, alpha-[2-(methylamino)ethyl]- 1-Phenyl-3-(methylamino)propane-1-ol N-Methyl-3-hydroxy-3-phenyl-1-propanamine N-Methyl-3-phenyl-3-hydroxypropylamine,97% N-Methyl 3-phenyl-3-hydroxy-1-propanaMine N-(3-Hydroxy-3-phenylpropyl)MethylaMine N-Methyl-N-(3-hydroxy-3-phenylpropyl)aMine 3-Hydroxy-N-methyl-3-phenylpropylamine 3-(Methylamino)-1-phenylpropanol Fluoxetine EP IMpurity A Methyl({3-[3-(2-Methylphenoxy)phenyl]propyl})aMine Fluoxertine EP impurity A -C (RS)-3-Methylamino-1-phenyl-1-propanol Fluoxertine EP impurity A 3-(methylamino)-1-phenylpropan-1-ol Oxalate Fluoxetine Impurity 1(EP-A) Atomoxetine Impurity 8(Atomoxetine EP Impurity H) Fluoxetine Hydrochloride Impurity Ⅰ:Fluoxetine EP Impurity A Fluoxetine Impurity 1 Atomoxetine EP Imp H 3-(Methylamino)-1-Phenyl-1-Ppropanol α-[2-(Methylamino)ethyl]benzylAlcohol> Fluoxetine EP Impurity A (Atomoxetine EP Impurity H) Atomoxetine USP RC A α-[2-(MethyL 3-Hydroxy-N-methyl-3-phenyl-propylamine USP/EP/BP Fluoxetine intermediate,3-Hydroxy-N-methyl-3-phenyl- propylamine Hydroxy-N-methyl-3-phenyl-propylamine ALPHA-[2-(METHYLAMINO)ETHYL]BENZYL Atomoxetine EP Impurity H/ Atomoxetine Related Compound A 3-Hydroxy-N-Methyl-3-Phenyl-Propylamine(42142-52-9) α-[2-(Methylamino)ethyl]benzyl Alcohol α-[2-(Methylamino)ethyl]benzenemethanol Fluoxetine Hydrochloride Impurity Ⅰ:Fluoxetine EP Impurity A (1RS)-3-(Methylamino)-1-phenylpropan-1-ol Atomoxetine Related Compound A (3-(Methylamino)-1-phenylpropan-1-ol) (1044470) 3-METHYLAMINO-1-PHENYLPROPANOL 3-(METHYLAMINO)-1-PHENYLPROPAN-1-OL