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ETHYLTHIOUREA

CAS No.
625-53-6
Chemical Name:
ETHYLTHIOUREA
Synonyms
N-ETHYLTHIOUREA;Nsc62921;Ent 61326;ETHYLTHIOUREA;1-ETHYLTHIOUREA;ethyl-2-thiourea;Thiourea, ethyl-;Ethylthiourea,99%;1-ETHYL-2-THIOUREA;1-ethyl-2-thio-ure
CBNumber:
CB6416447
Molecular Formula:
C3H8N2S
Molecular Weight:
104.17
MDL Number:
MFCD00004939
MOL File:
625-53-6.mol
MSDS File:
SDS
Last updated:2023-05-15 10:44:00

ETHYLTHIOUREA Properties

Melting point 108-110 °C(lit.)
Boiling point 132 °C
Density 1.055 (estimate)
refractive index 1.5500 (estimate)
storage temp. Store at RT
solubility methanol: soluble25mg/mL, clear, colorless
form Solid
pka 14.97±0.29(Predicted)
color White to Off-White
Water Solubility Soluble in water (24g/L).
BRN 1699551
InChIKey GMEHFXXZSWDEDB-UHFFFAOYSA-N
CAS DataBase Reference 625-53-6(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII U54OR2E97E
EPA Substance Registry System Ethylthiourea (625-53-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310+P330
Hazard Codes  T
Risk Statements  25
Safety Statements  36/37/39-45
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  YT3700000
TSCA  Yes
HazardClass  6.1
PackingGroup  III
Toxicity mouse,LDLo,oral,500mg/kg (500mg/kg),Teratology, The International Journal of Abnormal Development. Vol. 23, Pg. 335, 1981.
NFPA 704
1
3 0

ETHYLTHIOUREA price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 252530 N-Ethylthiourea 99% 625-53-6 10g $208 2024-03-01 Buy
Alfa Aesar B24761 N-Ethylthiourea, 99% 625-53-6 50g $253 2021-12-16 Buy
Alfa Aesar B24761 N-Ethylthiourea, 99% 625-53-6 10g $71.9 2021-12-16 Buy
Alfa Aesar B24761 N-Ethylthiourea, 99% 625-53-6 250g $1230 2021-12-16 Buy
TRC E926975 Ethylthiourea 625-53-6 10g $110 2021-12-16 Buy
Product number Packaging Price Buy
252530 10g $208 Buy
B24761 50g $253 Buy
B24761 10g $71.9 Buy
B24761 250g $1230 Buy
E926975 10g $110 Buy

ETHYLTHIOUREA Chemical Properties,Uses,Production

Uses

N-Ethylthiourea was used in the preparation of Re (III) complexes, which are precursors for the new rhenium complexes, potentially useful in nuclear medicine. It was also used in two-step protocol for the first chemoselective cleavage of 2-hydroxy acid amides

Definition

ChEBI: N-ethylthiourea is a member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by an ethyl group. It is functionally related to a thiourea.

General Description

N-Ethylthiourea forms adduct with silver halides and their single crystal X-ray structural and spectroscopic characterizations are described.

Biological Activity

Potent, selective and reversible inhibitor of isoform II NO synthase (IC 50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively).

Safety Profile

Poison by ingestion. SYN: 1-ETHYLTHIOUREA Experimental teratogenic effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Sox and NOx.

Purification Methods

Crystallise the thiourea from EtOH, MeOH or ether. [Beilstein 4 IV 374.]

ETHYLTHIOUREA Preparation Products And Raw materials

Raw materials

Preparation Products

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