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ChemicalBook >> CAS DataBase List >>(1S,2R)-(-)-cis-1-Amino-2-indanol

(1S,2R)-(-)-cis-1-Amino-2-indanol

(1S,2R)-(-)-cis-1-Amino-2-indanol Structure
(1S,2R)-(-)-cis-1-Amino-2-indanol structure
CAS No.
126456-43-7
Chemical Name:
(1S,2R)-(-)-cis-1-Amino-2-indanol
Synonyms
(1S,2R)-1-AMINO-2,3-DIHYDRO-1H-INDEN-2-OL;(1S,2R)-1-AMINO-2-INDANOL;(1S,2R)-CIS-1-AMINO-2-INDANOL;(1S,2R)-(-)-1-AMINO-2-INDANOL;CIS-(1S,2R)-1-AMINO-2-INDANOL;(1S;3aR;(1S,2R) -(−KT-1-Amino-2-indanol-0001;(1S,2R)-1-AMINO-INDAN-2-OL
CBNumber:
CB6417161
Molecular Formula:
C9H11NO
Molecular Weight:
149.19
MDL Number:
MFCD00216655
MOL File:
126456-43-7.mol
MSDS File:
SDS
Last updated:2024-04-23 16:18:34
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(1S,2R)-(-)-cis-1-Amino-2-indanol Properties

Melting point 118-121 °C(lit.)
alpha -62 º (c=0.5, CHCl3)
Boiling point 270.27°C (rough estimate)
Density 1.0753 (rough estimate)
refractive index 1.5760 (estimate)
RTECS NK7525500
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility soluble in Methanol
pka 14.79±0.40(Predicted)
form Powder
color White to light beige
optical activity [α]20/D 61°, c = 0.5 in chloroform
Water Solubility slightly soluble
Sensitive Air Sensitive
BRN 4292559
InChIKey LOPKSXMQWBYUOI-BDAKNGLRSA-N
CAS DataBase Reference 126456-43-7(CAS DataBase Reference)
FDA UNII LU3GK925A8

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-36-36/37/39
RIDADR  3259
WGK Germany  3
F  10-23
TSCA  No
HazardClass  8
HS Code  29052900
NFPA 704
0
2 0

(1S,2R)-(-)-cis-1-Amino-2-indanol price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 440833 (1S,2R)-(?)-cis-1-Amino-2-indanol 99% 126456-43-7 1g $26 2024-03-01 Buy
Sigma-Aldrich 440833 (1S,2R)-(?)-cis-1-Amino-2-indanol 99% 126456-43-7 5g $27.1 2024-03-01 Buy
TCI Chemical A1624 (1S,2R)-(-)-1-Amino-2-indanol >98.0%(GC)(T) 126456-43-7 1g $30 2024-03-01 Buy
TCI Chemical A1624 (1S,2R)-(-)-1-Amino-2-indanol >98.0%(GC)(T) 126456-43-7 5g $131 2024-03-01 Buy
Alfa Aesar H32066 (1S,2R)-(-)-cis-1-Amino-2-indanol, 97% 126456-43-7 5g $146.65 2024-03-01 Buy
Product number Packaging Price Buy
440833 1g $26 Buy
440833 5g $27.1 Buy
A1624 1g $30 Buy
A1624 5g $131 Buy
H32066 5g $146.65 Buy

(1S,2R)-(-)-cis-1-Amino-2-indanol Chemical Properties,Uses,Production

Reaction

  1. Ligand component used in the chromium-catalyzed highly selective asymmetric ene reactions between aryl aldehydes and alkoxy- and silyloxyalkenes.
  2. Ligand component for the chromium-catalyzed highly enantioselective o inverse-demand hetero-Diels-Alder reactions of α,β-unsaturated aldehydes.
  3. Ligand component for the magnesium-catalyzed conjugate addition reaction of 1,3-dicarbonyl compounds to nitroalkenes.
  4. Component for stereoselective asymmetric 6π-azaelectrocyclization through the reaction between the (E)-3-
  5. carbonyl-2,4,6-trienal compounds and the (-)-7-alkyl-cis-1-amino-2-indanol derivatives.
  6. Ligand component for palladium-catalzyed asymmetric azaelectrocyclization for the preparation of 2,4-
  7. disubstituted chiral 1,2,5,6-tetrahydropyridines.
  8. Component for organocatalytic conjugate addition of formaldehyde N,N-dialkylhydrazones to β,γ -Unsaturated α-keto esters.
  9. N-Sulfinyl urea organocatalyst component for enantioselective aza-henry reaction.
  10. Component for organocatalytic enantioselective additions of indoles to nitroalkenes.
Reactions of 126456-43-7_1
Reactions of 126456-43-7_2
Reactions of 126456-43-7_3
Reactions of 126456-43-7_4

Chemical Properties

white to light yellow crystal powder

Uses

(1S,2R)-(-)-cis-1-Amino-2-indanol is used as a reagent in the synthesis of heterocyclic compounds as integrase inhibiting antiviral agents. It is also a key intermediate of the HIV protease inhibitor, Indinavir (I525000).

Uses

1S,2R)-(-)-cis-1-Amino-2-indanol may be used to prepare:

  • (-)-1,2,5,6-Tetrahydropyridine by reacting with methyl (E,E)-4-oxo-2-[(2,6,6-trimethylcyclohex-1-enyl)vinyl}but-2-enoate.
  • Oxazaborolidine catalysts, which can catalyze the asymmetric reduction of aromatic ketones with high enantioselectivity.
  • (RS,1S,2R)-(-)-2,4,6-Trimethylbenzenesulfinic acid 1-(2,4,6-trimethylbenzenesulfonylamino)indan-2-yl ester.

General Description

(1S,2R)-(-)-cis-1-Amino-2-indanol is a main constituent of indinavir, a potent HIV (human immunodeficiency virus) protease inhibitor.

(1S,2R)-(-)-cis-1-Amino-2-indanol Preparation Products And Raw materials

Raw materials

Preparation Products

(1S,2R)-(-)-cis-1-Amino-2-indanol Suppliers

Global( 391)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12456 58
Ouhuang Engineering Materials (Hubei) Co., Ltd 		+8617702722807 admin@hbouhuang.com China 2259 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1807 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Shanghai Arbor Chemical Co., Ltd. 		021-60451682 act@arborchemical.com CHINA 906 58
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4242 58
Supplier Advantage
Hebei Mojin Biotechnology Co., Ltd 		58
Ouhuang Engineering Materials (Hubei) Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Shanghai Arbor Chemical Co., Ltd. 		58
Changzhou Ansciep Chemical Co., Ltd. 		58

View Lastest Price from (1S,2R)-(-)-cis-1-Amino-2-indanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(1S,2R)-(-)-cis-1-Amino-2-indanol pictures 2024-04-26 (1S,2R)-(-)-cis-1-Amino-2-indanol
126456-43-7
 US $5.00 / kg 1kg ≥99% 200mt/year Jinan Finer Chemical Co., Ltd
(1S,2R)-(-)-cis-1-Amino-2-indanol pictures 2024-04-23 (1S,2R)-(-)-cis-1-Amino-2-indanol
126456-43-7
 US $50.00 / kg 1kg 99.10% 50000kg Ouhuang Engineering Materials (Hubei) Co., Ltd
(1S,2R)-(-)-cis-1-Amino-2-indanol pictures 2023-07-29 (1S,2R)-(-)-cis-1-Amino-2-indanol
126456-43-7
 US $100.00 / kg 25kg 99.99% 200ton Hebei Mojin Biotechnology Co., Ltd

(1S,2R)-(-)-cis-1-Amino-2-indanol Spectrum

(1S,2R)-(-)-cis-1-Amino-2-indanol(126456-43-7)1HNMR(1S,2R)-(-)-cis-1-Amino-2-indanol(126456-43-7)IR

126456-43-7((1S,2R)-(-)-cis-1-Amino-2-indanol)Related Search:

Indinavir tert-Butanesulfinamide TERT-BUTYLSULFONAMIDE 6-Aminocaproic acid EC 2.6.1.2
4-Amino-benzenesulfonic acid monosodium salt Glycine 2-Indanol Sulfamic acid Aminopyrine
Glucosamine Tris(hydroxymethyl)aminomethane 2-Aminophenol ALTRENOGEST Acetaminophen
N-[N,O-ISOPROPYLIDENE-(2R)-HYDROXY INDAN-(1S)-YL]-(2R)-BENZYL-(4S,5)-EPOXY PENTANAMIDE [1(1S,2R),5(S)]-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-[2-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperazinyl]-2-(phenylmethyl)-D-erythro-pentonamide 3-(CHLOROMETHYL)PYRIDINE

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(1S,2R)-(-)-cis-1-Amino-2-indanol,99% (1S, 2R)-Trans-1-AMino-2-indanol (1S,2R)-(-)-1-Amino-2,3-dihydro-1H-inden-2-ol, (1S,2R)-(-)-1-Aminoindan-2-ol (1S,2R)-1-Amino-2,3-dihydro-inden-2-ol (1S,2R)-(-)-cis-1-Amino-2-indanol ,98% (1S 2R)-(-)-cis-1-AMino-2-indanol 3aR 7aR)-1-((S)-1-(3-(tert-butyldiMethylsilyloxy)-3-Methylbutoxy)ethyl) -7a-Methylhexahydro-1H-inden-4(2H)-one KT-1-Amino-2-indanol-0001 (1S,2R)-(-)-cis-1-Amino-2-indanol (1S,2R)-(-)-cis-1-Amino-2-hydroxyindane (1S,2R)-(-)-1-Amino-2-indanol, >=98% (1S,2R)-1-Amino-2-indanol,99%e.e. (1S,2R)-(-)-CIS-1-AMINO-2-HYDROXYINDANE (1S,2R)-(-)-CIS-1-AMINO-2-INDANOL (1S,2R)-(-)-CIS-1-AMINOINDAN-2-OL (1S,2R)-(+)-CIS-1-AMINOINDAN-2-OL (1S,2R)-(-)-1-AMINO-2-HYDROXYINDAN (1S,2R)-1-AMINO-2-HYDROXYINDANE (1S,2R)-1-AMINO-INDAN-2-OL cis-(1S)-Amino-(2R)-indanol (Is-Cis)L-Amino-2,3-Dihydro-Lh-Inden-2-Ol,IndinavirSulphate, (IS-cis) l-Amino-2,3-Dihydro-lH-Inden-2-ol CIS-(1S,2R)-1-AMINO-INDANE-2-OL (1S,2R)-(1)-cis-1-Amino-2-indanol (1S,2R)-(-)-cis-1-Aminoindan-2-ol,98% (1S,2R)-(-)-CIS-1-AMINO-2-INDANOL 99% (1R,2S)-(-)-cis-a-Amino-2-indanol 5R)-LGH447 dihydrochloride (1S,2R)-(-)-cis-1-Amino-2-hydroxyindane 126456-43-7 (1S,2R)-(-)-cis-1-Amino-2-indanol (1S,2R)-(-)-cis-1-Amino-2-indanol 126456-43-7 (1S,2R)-(-)-1-Amino-2-indanol > 1H-Inden-2-ol, 1-amino-2,3-dihydro-, (1S,2R)- Indinavir Impurity 1 （Indinavir EP Impurity A) (1S,2R)-(-)-cis-1-Amino-2-indanol USP/EP/BP (1S,2R)-(-)-cis-1-Amino-2-indanol, 97%, (1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-aminium (1S,2R)-CIS-1-AMINO-2-INDANOL (1S,2R)-1-AMINO-2,3-DIHYDRO-1H-INDEN-2-OL (1S,2R)-(-)-1-AMINO-2-INDANOL (1S,2R)-1-AMINO-2-INDANOL CIS-(1S,2R)-1-AMINO-2-INDANOL (1S,2R) -(&minus (1S,2R)-(-) -1-amino-2-indenol 126456-43-7 126456-43-9 C9H11NO Amino Alcohols (Chiral) Chiral Building Blocks Hydrogenation Organic Building Blocks Chiral Catalysts, Ligands, and Reagents Asymmetric Synthesis Amino Alcohols Chiral Nitrogen organic alcohol Amino Alcohols (Chiral) Chiral Building Blocks