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Thioflavine T

CAS No.
2390-54-7
Chemical Name:
Thioflavine T
Synonyms
THIOFLAVIN T;avin T;ThiofL;CI 49005;CI NO 49005;hioflavineT;Setoflavin T;THIOFLAVINE T;SETOFLAVINE T;BASIC YELLOW 1
CBNumber:
CB6676791
Molecular Formula:
C17H19ClN2S
Molecular Weight:
318.86
MDL Number:
MFCD00011944
MOL File:
2390-54-7.mol
Last updated:2024-04-24 17:21:45

Thioflavine T Properties

Melting point 211-212 °C (decomp)
Density 1.301g/cm3 at 20℃
vapor pressure 0Pa at 25℃
storage temp. Store below +30°C.
solubility methanol: soluble1mg/mL
Colour Index 49005
form Powder
color Yellow to ochre-yellow
BRN 3922452
LogP 3.02 at 25℃ and pH7.98
CAS DataBase Reference 2390-54-7(CAS DataBase Reference)
FDA UNII CAX9SG0II0
EPA Substance Registry System Benzothiazolium, 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-, chloride (2390-54-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Safety Statements  24/25
RIDADR  2811
WGK Germany  3
TSCA  Yes
HazardClass  6.1(b)
PackingGroup  III
HS Code  32041300
NFPA 704
0
3 0

Thioflavine T price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T3516 Thioflavin T used as stain for amyloid 2390-54-7 5g $36.6 2024-03-01 Buy
Sigma-Aldrich 8.40072 Thioflavine T (C.I.No.49005) ≥73% sulfur basis 2390-54-7 5G $102 2024-03-01 Buy
Sigma-Aldrich 596200 Thioflavin T 2390-54-7 500mg $123 2024-03-01 Buy
TCI Chemical T0558 Basic Yellow 1 2390-54-7 25g $73 2024-03-01 Buy
Alfa Aesar J61043 Thioflavine T, tech. 75% 2390-54-7 5g $21.65 2024-03-01 Buy
Product number Packaging Price Buy
T3516 5g $36.6 Buy
8.40072 5G $102 Buy
596200 500mg $123 Buy
T0558 25g $73 Buy
J61043 5g $21.65 Buy

Thioflavine T Chemical Properties,Uses,Production

Chemical Properties

yellow to ochre-yellow powder

Uses

A dye used to visualize beta-amyloid plaques, like those associated with Alzheimer's Disease

Uses

Textile dyeing, fluorescent sign paints, in combination with green or blue pigments to produce brilliant greens, phosphotungstic pigments.

Definition

ChEBI: Thioflavine T is an organic chloride salt having 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium as the counterion. It is widely used to visualise and quantify the presence of amyloids, both in vitro and in vivo. It has a role as a fluorochrome, a histological dye and a geroprotector. It contains a thioflavin T cation.

Preparation

4-(6-Methyl-2,3-dihydrobenzo[d]thiazol-2-yl)benzenamine?with methanol and hydrochloric acid or sulfuric acid, at 160 ~ 170 ℃ methylation under pressure.

General Description

Thioflavin T is a benzothiazole dye that increases in fluorescence upon binding to amyloid. Thioflavin T has been used in histology and for protein characterization.

Biochem/physiol Actions

Cell permeable: yes

storage

Store at -20°C

Properties and Applications

colourful green light yellow. Soluble in cold water, soluble in hot water for yellow, easily soluble in ethanol and yellow, with green fluorescent. The strong sulfuric acid to colorless, a green fluorescent, diluted into light yellow.

Standard( Silk ) Light Fastness Persperation Fastness Ironing Fastness Soaping
Fading Stain Fading Stain Fading Stain
C 3 2-3 4 1

Purification Methods

Crystallise the chloride from *benzene/EtOH (1:1). [Beilstein 27 III/IV 5052.]

Thioflavine T Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 277)Suppliers
Supplier Tel Email Country ProdList Advantage
Honest Joy Holdings Limited
0755-36694831 +8613717124449 sale@feiyang.com.cn China 300 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12456 58
Ouhuang Engineering Materials (Hubei) Co., Ltd
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Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
career henan chemical co
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Win-Win Chemical CO., Limited
0086-577-64498589 sales@win-winchemical.com CHINA 998 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49390 58

View Lastest Price from Thioflavine T manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Thioflavine T pictures 2024-04-24 Thioflavine T
2390-54-7
US $10.00 / kg 1kg 99.9% 200000kg Ouhuang Engineering Materials (Hubei) Co., Ltd
Thioflavine T pictures 2023-06-22 Thioflavine T
2390-54-7
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
Thioflavine T pictures 2021-07-08 Thioflavine T
2390-54-7
US $1.00 / PCS 1KG 99% 10 mt Hebei Guanlang Biotechnology Co., Ltd.
  • Thioflavine T pictures
  • Thioflavine T
    2390-54-7
  • US $10.00 / kg
  • 99.9%
  • Ouhuang Engineering Materials (Hubei) Co., Ltd
  • Thioflavine T pictures
  • Thioflavine T
    2390-54-7
  • US $0.00 / KG
  • 99%
  • Hebei Mojin Biotechnology Co., Ltd
  • Thioflavine T pictures
  • Thioflavine T
    2390-54-7
  • US $1.00 / PCS
  • 99%
  • Hebei Guanlang Biotechnology Co., Ltd.
2-[4-(dimethylamino)phenyl]-3,6-dimethyl-benzothiazoliuchloride Benzothiazolium,2-[4-(dimethylamino)phenyl]-3,6-dimethyl-,chloride Thioflavine T (C.I.No.49005) for synthesis LABOTEST-BB LT00451909 BASIC YELLOW 1 CI 49005 CI NO 49005 SETOFLAVINE T THIOFLAVINE T THIOFLAVINE TG THIOFLAVINE T, TCN, TG 2-[4-(dimethylamino)phenyl]-3,6-dimethylbenzothiazolium chloride THIOFLAVINET,TG Basic yellow 1 (C.I. 49005) THIOFLAVINE T, FOR MICROSCOPY ThioflavineTC.I.49005 C.I. Basic Yellow 1 Basic Yellow1, Thioflavine T 4-(3,6-Dimethyl-1,3-benzothiazol-3-ium-2-yl)-N,N-dimethylaniline chloride Setoflavin T Thioflavine TCN Thioflavin T 25GR Thioflavin T 5GR Setoflavine T Thioflavine T Acronol Yellow T 2-(4-(DiMethylaMino)phenyl)-3,6-diMethylbenzo[d]thiazol-3-iuM chloride ThioflavinT,Basic Yellow1, Thioflavine T Thioflavin T (Absorbance(E1%1cm) >=750 (410 nm to 414 nm, H2O) Thioflavin T *CAS 2390-54-7* avin T ThiofL Thioflavin T - CAS 2390-54-7 - Calbiochem Thioflavine T (C.I.No.49005) Benzothiazolium,2-[4-(dimethylamino)phenyl]-3,6-dimethyl-, chloride (1:1) Thioflavine T (C.I.No.405) THIOFLAVINE T (C.I.NO.49005) FOR SYNTHES hioflavineT C.I.Basic Yellow 1:C.I.49005 thioflavin T (c.i. 49005) 2-[4-(dimethylamino)phenyl]-3,6-dimethylbenzothiazolium chlo... TIANFUCHEM-- 2390-54-7--High purity Thioflavine T in stock Thioflavin T for microscopy (C.I. No. 49005), 90% THIOFLAVINE T Extra Pure THIOFLAVIN T 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium chloride 2390-54-7 C17H19ClN2S C17H19N2SCl C17H19CN2S Detection Fluorescent Probes, Labels, Particles and Stains Biochemicals and Reagents BioChemical Biochemistry Vitamin Derivatives Vitamins