ChemicalBook >> CAS DataBase List >>Trimethyl phosphonoacetate
Trimethyl phosphonoacetate
- CAS No.
- 5927-18-4
- Chemical Name:
- Trimethyl phosphonoacetate
- Synonyms
- TMPA;METHYL DIMETHYLPHOSPHONOACETATE;Methyl (dimethoxyphosphoryl)acetate;NSC 84262;TriMethyl phosphonoacetat;TRIMETHYL PHOPHONOACETATE;trimethylacetyl phosphate;Trimethylphosphoroacetate;TRIMETHYL PHOSPHONACETATE;RIMETHYL PHOSPHONOACETATE
- CBNumber:
- CB6726270
- Molecular Formula:
- C5H11O5P
- Molecular Weight:
- 182.11
- MDL Number:
- MFCD00008452
- MOL File:
- 5927-18-4.mol
Last updated:2024-04-23 16:18:34
| Melting point | 242 °C |
|---|---|
| Boiling point | 118 °C0.85 mm Hg(lit.) |
| Density | 1.125 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Liquid |
| Specific Gravity | approximate 1.265ｇ/ml (20℃) |
| color | Clear colorless to light yellow |
| Water Solubility | Slightly miscible with water. |
| BRN | 1865177 |
| LogP | -0.680 (est) |
| CAS DataBase Reference | 5927-18-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Trimethyl phosphonoacetate(5927-18-4) |
| EPA Substance Registry System | Acetic acid, (dimethoxyphosphinyl)-, methyl ester (5927-18-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H227-H315-H319-H335 | |||||||||
| Precautionary statements | P210e-P261-P280a-P305+P351+P338-P405-P501a | |||||||||
| Safety Statements | 23-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 9 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29310095 | |||||||||
| NFPA 704 |
|
Trimethyl phosphonoacetate price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T79758 | Trimethyl phosphonoacetate 98% | 5927-18-4 | 25g | $102 | 2024-03-01 | Buy |
| Sigma-Aldrich | T79758 | Trimethyl phosphonoacetate 98% | 5927-18-4 | 100g | $125 | 2024-03-01 | Buy |
| TCI Chemical | P1265 | Trimethyl Phosphonoacetate >96.0%(GC) | 5927-18-4 | 25g | $52 | 2024-03-01 | Buy |
| TCI Chemical | P1265 | Trimethyl Phosphonoacetate >96.0%(GC) | 5927-18-4 | 250g | $243 | 2024-03-01 | Buy |
| Alfa Aesar | A13301 | Trimethyl phosphonoacetate, 98% | 5927-18-4 | 25g | $42.65 | 2024-03-01 | Buy |
Trimethyl phosphonoacetate Chemical Properties,Uses,Production
Chemical Properties
clear colorless to light yellow liquid
Uses
Trimethyl phosphonoacetate is used in the preparation of sarin A by intramolecular Mannich-type reactions. It is involved in the Horner-Wadsworth-Emmons olefination with aldehydes and ketones to give acrylic esters. It is also involved in oxa-Michael reactions, prenylation of oxindoles and heterocyclization reactions.
Application
Trimethyl phosphonoacetate is an important Wittig-horner reagent, which can be used to manufacture important intermediates of natural compounds such as vitamins, drugs, insect pheromones, etc.
Reactant involved in:
Intramolecular Mannich-type reactions to produce the sarain A diazatricyclic core
Organocatalytic oxa-Michael reactions
Prenylation and geranylation of oxindoles
Intramolecular Horner-Wadsworth-Emmons reactions
Olefin cross-metathesis / heterocyclization
Definition
ChEBI: Trimethyl phosphonoacetate is a phosphonic ester.
Trimethyl phosphonoacetate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 371)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangxi Sunway Chemical Co., Ltd. | +86-0794-5259909 +8615888611133 | dave@jxswchem.com | China | 22 | 58 |
| Jiangxi Sunway Chemical Co., Ltd. | +86-0794-5259909 +8615888611133 | dave@jxswchem.com | China | 22 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 | daisy@crovellbio.com | China | 5964 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 951 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 2880 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15933 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
Related articles
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- Jan 23，2024
View Lastest Price from Trimethyl phosphonoacetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-28 | Trimethyl phosphonoacetate
5927-18-4
|
US $30.00 / kg | 1kg | 98% | 2000kg | hebei hongtan Biotechnology Co., Ltd | |
 |
2024-04-23 | Trimethyl phosphonoacetate
5927-18-4
|
US $10.00 / kg | 1kg | 99.6% | 100000 | Ouhuang Engineering Materials (Hubei) Co., Ltd | |
 |
2023-11-29 | Trimethyl phosphonoacetate
5927-18-4
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
-
- Trimethyl phosphonoacetate
5927-18-4
- US $30.00 / kg
- 98%
- hebei hongtan Biotechnology Co., Ltd
-
- Trimethyl phosphonoacetate
5927-18-4
- US $10.00 / kg
- 99.6%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
-
- Trimethyl phosphonoacetate
5927-18-4
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
5927-18-4(Trimethyl phosphonoacetate)Related Search:
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NSC 84262
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TrimethylPhosphonoacetate>
Trimethyl phosphonoacetate, 98%, for synthesis
Trimethyl phosphonylacetate
RIMETHYL PHOSPHONOACETATE
TMPA
METHYL DIMETHYLPHOSPHONOACETATE
Methyl (dimethoxyphosphoryl)acetate
Phosphonyl acetate trimethyl ester
5927-18-4
CH3O2POCH2CO2CH3
C5H11O5P
Horner-Wadsworth-Emmons Reagents
Olefination
Synthetic Reagents
Wittig & Horner-Emmons Reaction
Horner-Emmons Reaction
C-C Bond Formation
Horner-Emmons Reaction
Synthetic Organic Chemistry
Wittig & Horner-Emmons Reaction
C-C Bond Formation
Horner-Wadsworth-Emmons Reagents
Olefination
5927-18-4