Menlaquinone 7
- CAS No.
- 2124-57-4
- Chemical Name:
- Menlaquinone 7
- Synonyms
- MK-7;MENAQUINONE-7;Vitamin K2-7;Menlaquinone 7;Menaquinone 7, Synthetic (90%);Vitamin MK 7;Vitamin K2(35);Menaquinone K7;Menaquinone-7(MK-7);Menatetrenone (MK-7)
- CBNumber:
- CB7206357
- Molecular Formula:
- C46H64O2
- Molecular Weight:
- 649
- MDL Number:
- MFCD06200757
- MOL File:
- 2124-57-4.mol
- MSDS File:
- SDS
| Melting point | 54 °C |
|---|---|
| Boiling point | bp0.0002 200° (some dec) |
| Density | 0.961 |
| storage temp. | -20°C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Pale Yellow to Yellow |
| Stability | Light and Temperature Sensitive |
| InChIKey | RAKQPZMEYJZGPI-LJWNYQGCSA-N |
| SMILES | C1(=O)C2=C(C=CC=C2)C(=O)C(C)=C1C/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(/C)\C |
| LogP | 14.451 (est) |
| FDA UNII | 8427BML8NY |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2936299055 |
Menlaquinone 7 price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 900074 | Vitamin K2 (MK-7)-(5,6,7,8-d4,2-methyl-d3) ≥98 atom % D, ≥95% (CP) | 2124-57-4 | 1MG | $2420 | 2024-03-01 | Buy |
| Cayman Chemical | 10011051 | Menaquinone 7 ≥98% | 2124-57-4 | 1mg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 10011051 | Menaquinone 7 ≥98% | 2124-57-4 | 5mg | $481 | 2024-03-01 | Buy |
| Cayman Chemical | 10011051 | Menaquinone 7 ≥98% | 2124-57-4 | 10mg | $841 | 2024-03-01 | Buy |
| TRC | M218600 | Menaquinone7,Synthetic(90%) | 2124-57-4 | 50mg | $275 | 2021-12-16 | Buy |
Menlaquinone 7 Chemical Properties,Uses,Production
Description
Menaquinone 7 (MK-7) is a vitamin K2 analog that has been found in a variety of fermented foods. It increases osteocalcin, osteoprotegerin, and RANKL mRNA expression in osteoblastic MC3T3E cells. MK-7 (1 μM) increases alkaline phosphatase activity and calcium content in femoral-metaphyseal tissues isolated from normal and skeletal-unloaded rats. In vivo, MK-7 (100 μg/g diet) inhibits aortic and myocardial calcification and decreases aortic alkaline phosphatase tissue concentrations in a rat model of extraosseous calcification. It also increases trabecular number, bone mineral density, and bone mineral content in a rat model of ovariectomy-induced bone loss.
Chemical Properties
Light Yellow Crystalline Solid
Uses
Vitamin (prothrombogenic)
Uses
Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a vari ety of physiological processes. Menaquinone 7 belongs to the class of K2-Vitamins homologs. Menaquinone 7 has been identified as the most bioactive cofactor for the carboxylation reaction of Gla-prote ins such as osteocalcin and matrix-Gla protein, which plays a crucial role in building and maintaining overall bone health.
Uses
Vitamin K2 (MK-7)-(5,6,7,8-d4,2-methyl-d3) can be used as a stable isotope internal standard for data interpretation in specific biological samples.
Definition
ChEBI: A menaquinone whose side-chain contains seven isoprene units in an all-trans-configutation.
General Description
Vitamin K2, also known as menaquinone, is a polyisoprenoid-substituted?napthoquinone. Menaquinone-7 (MK-7) is a subtype of vitamin K2. It is found in animals, soy protein, fermented products and is primarily produced by bacteria.
Vitamin K2 (MK-7)-(5,6,7,8-d4,2-methyl-d3) is a deuterated vitamin K2 wherein C-5, C-6, C-7, C-8, and 2-methyl protons are replaced by deuterium.
Side effects
Menlaquinone 7 is usually well tolerated and side effects are rare. Mild digestive symptoms, such as nausea, bloating or diarrhoea, may occur with overdose, but these side effects are usually temporary and will subside on their own. There have been some reports of allergic reactions to Vitamin K2 MK7, including skin rashes and breathing difficulties. As Menlaquinone 7 interferes with the action of blood thinners such as warfarin. Therefore, if you are taking blood thinners, be sure to consult your healthcare provider before taking Vitamin K2 MK7 or any other vitamin or supplement. Therefore, if you are taking blood thinners, be sure to consult your healthcare provider before taking Vitamin K2 MK7 or any other vitamin or supplement.
Menlaquinone 7 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10297 | 58 |
| Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd. | +86-029-86185165 +8618629664246 | guoyuan@eastchinapharm.com | China | 1615 | 58 |
| Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 | sales006@ingredients-lonier.com | China | 2596 | 58 |
| Leading Chemical and Trading Co.,Ltd | +8615669938129 | sales@leadingchemical.com | China | 121 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 992 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 8095 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 | sarah@tnjone.com | China | 902 | 58 |
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 311 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15933 | 58 |
View Lastest Price from Menlaquinone 7 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-25 | Vitamin K2 mk7
2124-57-4
|
US $0.00 / kg | 1kg | 99% | 1000kg | Shaanxi TNJONE Pharmaceutical Co., Ltd | |
 |
2024-04-22 | Vitamin K2 MK-7
2124-57-4
|
US $450.00-250.00 / Kg/Bag | 1Kg/Bag | 99% up, High Density | 20 tons | Sinoway Industrial co., ltd. | |
 |
2024-04-22 | Menlaquinone 7
2124-57-4
|
US $0.00 / kg | 1kg | 99.8% | 1000 kg | BINBO BIOLOGICAL CO.,LTD |
-
- Vitamin K2 mk7
2124-57-4
- US $0.00 / kg
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd
-
- Vitamin K2 MK-7
2124-57-4
- US $450.00-250.00 / Kg/Bag
- 99% up, High Density
- Sinoway Industrial co., ltd.
-
- Menlaquinone 7
2124-57-4
- US $0.00 / kg
- 99.8%
- BINBO BIOLOGICAL CO.,LTD