メナキノン7 化学特性,用途語,生産方法
外観
黄色, 結晶性粉末〜粉末
溶解性
ヘキサンに溶ける。
用途
ビタミンＫをＨＰＬＣ分析する際の標準品として使用します。
使用上の注意
不活性ガス封入
説明
Menaquinone 7 (MK-7) is a vitamin K
2 analog that has been found in a variety of fermented foods. It increases osteocalcin, osteoprotegerin, and RANKL mRNA expression in osteoblastic MC3T3E cells. MK-7 (1 μM) increases alkaline phosphatase activity and calcium content in femoral-metaphyseal tissues isolated from normal and skeletal-unloaded rats.
In vivo, MK-7 (100 μg/g diet) inhibits aortic and myocardial calcification and decreases aortic alkaline phosphatase tissue concentrations in a rat model of extraosseous calcification. It also increases trabecular number, bone mineral density, and bone mineral content in a rat model of ovariectomy-induced bone loss.
化学的特性
Light Yellow Crystalline Solid
使用
Vitamin (prothrombogenic)
定義
ChEBI: A menaquinone whose side-chain contains seven isoprene units in an all-trans-configutation.
一般的な説明
Vitamin K2, also known as menaquinone, is a polyisoprenoid-substituted?napthoquinone. Menaquinone-7 (MK-7) is a subtype of vitamin K2. It is found in animals, soy protein, fermented products and is primarily produced by bacteria.
Vitamin K2 (MK-7)-(5,6,7,8-d
4,2-
methyl-d
3) is a deuterated vitamin K2 wherein C-5, C-6, C-7, C-8, and 2-methyl protons are replaced by deuterium.
副作用
Menlaquinone 7 is usually well tolerated and side effects are rare. Mild digestive symptoms, such as nausea, bloating or diarrhoea, may occur with overdose, but these side effects are usually temporary and will subside on their own. There have been some reports of allergic reactions to Vitamin K2 MK7, including skin rashes and breathing difficulties. As Menlaquinone 7 interferes with the action of blood thinners such as warfarin. Therefore, if you are taking blood thinners, be sure to consult your healthcare provider before taking Vitamin K2 MK7 or any other vitamin or supplement.
Therefore, if you are taking blood thinners, be sure to consult your healthcare provider before taking Vitamin K2 MK7 or any other vitamin or supplement.
メナキノン7 上流と下流の製品情報
原材料
Naphthalene, 2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosaheptaen-1-yl]-1,4-dimethoxy-3-methyl-
準備製品