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GW 610

CAS No.
872726-44-8
Chemical Name:
GW 610
Synonyms
GW 610;NSC 721648;NSC 721648 PMX 610;NSC 721648 - CAS 872726-44-8 - Calbiochem;2-(3,4-Dimethoxyphenyl)-5-fluorobenzo[d]thiazole;Benzothiazole, 2-(3,4-dimethoxyphenyl)-5-fluoro-;GW 610,colon,Inhibitor,GW610,NSC721648,inhibit,breast,antitumor,NSC 721648,lung,GW-610,NSC-721648
CBNumber:
CB72591189
Molecular Formula:
C15H12FNO2S
Molecular Weight:
289.3246832
MDL Number:
MFCD12024619
MOL File:
872726-44-8.mol
Last updated:2023-09-20 16:43:00

GW 610 Properties

Melting point 110 °C
Boiling point 422.8±55.0 °C(Predicted)
Density 1.293±0.06 g/cm3(Predicted)
storage temp. +2C to +8C
solubility DMF:10.0(Max Conc. mg/mL);34.56(Max Conc. mM)
DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.86(Max Conc. mM)
DMSO:9.5(Max Conc. mg/mL);32.84(Max Conc. mM)
form White crystalline solid
pka 0.73±0.10(Predicted)
FDA UNII X3XWA9LQ3Q

GW 610 price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10008313 GW 610 ≥98% 872726-44-8 1mg $22 2024-03-01 Buy
Cayman Chemical 10008313 GW 610 ≥98% 872726-44-8 5mg $95 2024-03-01 Buy
Cayman Chemical 10008313 GW 610 ≥98% 872726-44-8 10mg $167 2024-03-01 Buy
Cayman Chemical 10008313 GW 610 ≥98% 872726-44-8 50mg $723 2024-03-01 Buy
TRC G929500 GW610 872726-44-8 5mg $70 2021-12-16 Buy
Product number Packaging Price Buy
10008313 1mg $22 Buy
10008313 5mg $95 Buy
10008313 10mg $167 Buy
10008313 50mg $723 Buy
G929500 5mg $70 Buy

GW 610 Chemical Properties,Uses,Production

Description

GW 610 is an antitumor benzothiazole that shows growth-inhibitory activity against several cancer cell lines. In MCF-7 and MDA 468 human cancer cell lines, potent antiproliferative activity (growth inhibition (GI50) < 0.1 nM) was observed. Potent and selective activity was also observed in the NCI 60 human cancer cell line panel. In contrast with previously reported 2-(4-aminophenyl)benzothiazoles, GW 610 is not reliant on induction of cytochrome P 1A1 (CYP1A1) expression for antitumor activity.

Uses

GW 610 is a fluorinated 2-arylbenzothiazole and potential antitumor drug, which shows potent and selective inhibitory activity against breast, lung, and colon cancer cell lines. Studies suggest that the species-specific partial agonism of the aryl hydrocarbon receptor shown by GW 610 plays an important role in its anti-proliferative activity.

GW 610 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 47)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Dongying Sifang Litong New Material Co. LTD 17861826421 dysflt@126.com China 276 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8073 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 3445 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55896 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Hefei Mokai Pharmaceutical Technology Co., Ltd 18130062233 3362556465@qq.com China 8000 58
Bide Pharmatech Ltd. 400-1647117 15221909166 product02@bidepharm.com China 61720 58

GW 610 Spectrum

GW 610 NSC 721648 NSC 721648 - CAS 872726-44-8 - Calbiochem NSC 721648 PMX 610 GW 610,colon,Inhibitor,GW610,NSC721648,inhibit,breast,antitumor,NSC 721648,lung,GW-610,NSC-721648 Benzothiazole, 2-(3,4-dimethoxyphenyl)-5-fluoro- 2-(3,4-Dimethoxyphenyl)-5-fluorobenzo[d]thiazole 872726-44-8 Aromatics Heterocycles Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals