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GW 610

GW 610 구조식 이미지

카스 번호:: 872726-44-8

상품명:: GW 610

동의어(영문):: GW 610;NSC 721648;NSC 721648 PMX 610;NSC 721648 - CAS 872726-44-8 - Calbiochem;2-(3,4-Dimethoxyphenyl)-5-fluorobenzo[d]thiazole;Benzothiazole, 2-(3,4-dimethoxyphenyl)-5-fluoro-;GW 610,colon,Inhibitor,GW610,NSC721648,inhibit,breast,antitumor,NSC 721648,lung,GW-610,NSC-721648

CBNumber:: CB72591189

분자식:: C15H12FNO2S

포뮬러 무게:: 289.3246832

MOL 파일:: 872726-44-8.mol

속성

안전

용도

공급 업체 47

GW 610 속성

녹는점: 110 °C

끓는 점: 422.8±55.0 °C(Predicted)

밀도: 1.293±0.06 g/cm3(Predicted)

저장 조건: +2C to +8C

용해도: DMF:10.0(Max Conc. mg/mL);34.56(Max Conc. mM)
DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.86(Max Conc. mM)
DMSO:9.5(Max Conc. mg/mL);32.84(Max Conc. mM)

물리적 상태: 백색 결정성 고체

산도 계수 (pKa): 0.73±0.10(Predicted)

안전

GW 610 C화학적 특성, 용도, 생산

개요

GW 610 is an antitumor benzothiazole that shows growth-inhibitory activity against several cancer cell lines. In MCF-7 and MDA 468 human cancer cell lines, potent antiproliferative activity (growth inhibition (GI₅₀) < 0.1 nM) was observed. Potent and selective activity was also observed in the NCI 60 human cancer cell line panel. In contrast with previously reported 2-(4-aminophenyl)benzothiazoles, GW 610 is not reliant on induction of cytochrome P 1A1 (CYP1A1) expression for antitumor activity.

용도

GW 610 is a fluorinated 2-arylbenzothiazole and potential antitumor drug, which shows potent and selective inhibitory activity against breast, lung, and colon cancer cell lines. Studies suggest that the species-specific partial agonism of the aryl hydrocarbon receptor shown by GW 610 plays an important role in its anti-proliferative activity.

GW 610 준비 용품 및 원자재

원자재

준비 용품

GW 610 공급 업체

글로벌( 47)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Dongying Sifang Litong New Material Co. LTD	13589435123 17861826421	dysflt@126.com	China	286	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Shanghai TaoSu Biochemical Technology Co., Ltd.	021-33632979	info@tsbiochem.com	China	8073	58
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	3501	55
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55936	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
Hefei Mokai Pharmaceutical Technology Co., Ltd	18130062233	3362556465@qq.com	China	8000	58
Bide Pharmatech Ltd.	400-1647117 15221909166	product02@bidepharm.com	China	63720	58