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trans-Cinnamic acid

CAS No.
140-10-3
Chemical Name:
trans-Cinnamic acid
Synonyms
3-PHENYLACRYLIC ACID;CINNAMIC ACID, TRANS-;3-PHENYL-2-PROPENOIC ACID;(E)-Cinnamic acid;(e)-2-propenoicaci;(E)-3-Phenylacrylic acid;TRANS-3-PHENYLACRYLIC ACID;trans-Cinnamicacid 140-10-3;(2E)-3-phenylprop-2-enoic acid;2-Propenoic acid, 3-phenyl-, (E)-
CBNumber:
CB7345386
Molecular Formula:
C9H8O2
Molecular Weight:
148.16
MDL Number:
MFCD00004369
MOL File:
140-10-3.mol
MSDS File:
SDS
Last updated:2024-01-08 17:23:13

trans-Cinnamic acid Properties

Melting point 133 °C (lit.)
Boiling point 300 °C(lit.)
Density 1.248
vapor pressure 1.3 hPa (128 °C)
refractive index 1.5049 (estimate)
Flash point >230 °F
storage temp. 2-8°C
solubility 0.4g/l
form Crystalline Powder
pka 4.44(at 25℃)
color White to almost white
Specific Gravity 0.91
Odor Faint odour
PH Range 3 - 4
PH 3-4 (0.4g/l, H2O, 20℃)
Odor Type balsamic
Water Solubility 0.4 g/L (20 ºC)
λmax 273nm(MeOH)(lit.)
Merck 14,2299
BRN 1905952
Stability Light Sensitive
InChIKey WBYWAXJHAXSJNI-VOTSOKGWSA-N
LogP 2.130
CAS DataBase Reference 140-10-3(CAS DataBase Reference)
FDA UNII U14A832J8D
NIST Chemistry Reference Cinnamic acid(140-10-3)
EPA Substance Registry System (E)-Cinnamic acid (140-10-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P305+P351+P338-P261-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  1
RTECS  GD7850000
TSCA  Yes
HS Code  29163900
Toxicity LD50 orally in Rabbit: 2500 mg/kg LD50 dermal Rabbit > 5000 mg/kg
NFPA 704
1
2 0

trans-Cinnamic acid price More Price(56)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W228826 trans-Cinnamic Acid natural, ≥99%, FCC, FG 140-10-3 25g $83.9 2024-03-01 Buy
Sigma-Aldrich W228826 trans-Cinnamic Acid natural, ≥99%, FCC, FG 140-10-3 100g $159 2024-03-01 Buy
Sigma-Aldrich W228826 trans-Cinnamic Acid natural, ≥99%, FCC, FG 140-10-3 1kg $656 2024-03-01 Buy
Sigma-Aldrich W228818 trans-Cinnamic Acid ≥99%, FG 140-10-3 1kg $80.9 2024-03-01 Buy
Sigma-Aldrich W228818 trans-Cinnamic Acid ≥99%, FG 140-10-3 10Kg $603 2024-03-01 Buy
Product number Packaging Price Buy
W228826 25g $83.9 Buy
W228826 100g $159 Buy
W228826 1kg $656 Buy
W228818 1kg $80.9 Buy
W228818 10Kg $603 Buy

trans-Cinnamic acid Chemical Properties,Uses,Production

Chemical Properties

White to almost white crystalline powder. Insoluble in water, slightly soluble in hot water, easily soluble in benzene, acetone, ether, glacial acetic acid and other organic solvents.

Uses

trans-Cinnamic acid was used to establish library of phenolic compounds by liquid chromatography/ultraviolet and mass spectrometry/mass spectrometry.

Uses

trans-Cinnamic acid is used in flavors, synthetic indigo and pharmaceuticals. It is involved in the production of methyl, ethyl and benzyl esters, which is used in the perfume industry. It serves as a precursor to the sweetener aspartame through enzyme-catalyzed amination to phenylalanine. It is a self-inhibitor produced by fungal spores to prevent germination. In addition, it is used to establish phenolic compounds by liquid chromatography, ultraviolet and mass spectrometry. It is utilized as a potential agent, thereby preventing lung tumor cells from metastasizing. Further, it induces intracellular release of calcium ions from the vacuole to the cytoplasm in order to trigger phytotoxicity in cucumber.

Definition

ChEBI: Cinnamic acid is a monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 3-position. It is found in Cinnamomum cassia. It has a role as a plant metabolite. It is a member of styrenes and a member of cinnamic acids. It is a conjugate acid of a cinnamate.

General Description

trans-Cinnamic acid is an α,β-unsaturated aromatic acid that can be used as a flavoring agent. It is mainly used to prepare ester derivatives that are used in perfume industry. trans-Cinnamic acid is the key volatile components of cinnamon essential oil.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

trans-cinnamic acid has inhibitory effect on phorbol-12-myristate-13-acetate-induced invasion of human lung adenocarcinoma A549 cells. It is a potential agent which can prevent lung tumor cells from metastasizing. It induces intracellular release of Ca2+ from the vacuole to the cytoplasm which triggers phytotoxicity in cucumber.

Purification Methods

Crystallise the acid from *benzene, CCl4, hot water, water/EtOH (3:1), or 20% aqueous EtOH. Dry it at 60o in vacuo. It is steam volatile. [Beilstein 9 IV 2002.]

14371-10-9
140-10-3
Synthesis of trans-Cinnamic acid from trans-Cinnamaldehyde
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View Lastest Price from trans-Cinnamic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
trans-Cinnamic acid pictures 2024-01-08 trans-Cinnamic acid
140-10-3
US $0.00 / kg 1kg 99% 1000000 Hebei Jingbo New Material Technology Co., Ltd
Cinnamic acid pictures 2023-11-21 Cinnamic acid
140-10-3
US $1.00 / g 1000g 99% 20ton/month Wuhan Aoliqisi New Material Technology Co., Ltd.
trans-Cinnamic acid pictures 2023-09-25 trans-Cinnamic acid
140-10-3
US $115.00 / kg 1kg 99.99% 20ton/month Anhui Yisheng Technology Co., LTD
  • Cinnamic acid pictures
  • Cinnamic acid
    140-10-3
  • US $1.00 / g
  • 99%
  • Wuhan Aoliqisi New Material Technology Co., Ltd.
(E)-3-Phenyl-2-propenoic acid CINNAMIC ACID, TRANS-(SG) trans-Ciamic acid (2E)-3-Phenylprop-2-enoic acid, (E)-3-Phenylacrylic acid trans-Cinamic acid CINNAMIC ACID extrapure cinnamic acid,β-phenyl acrylic acid trans-b-Carboxystyrene (E)-3-Phenylpropenoic acid BETA-PHENYLACRYLIC ACID RARECHEM BK HC T302 2-PROPENOIC ACID, 3-PHENYL-, (2E)- AKOS 233-01 3-STYRYLACRYLIC ACID trans-CinnaMic acid, 98+% 100GR trans-CinnaMic acid, 98+% 500GR trans-CinnaMic acid, 98+% 5GR trans-Cinnamic acid,trans-3-Phenylacrylic acid, Cinnamic acid Hedyotis diffusa Willd. (e)-3-phenyl-2-propenoicacid (e)-cinnamicaci (e)-cinnamicacid (E)-Zimtsαure 2-propenoicacid,3-phenyl- 2-Propenoicacid,3-phenyl-, 3-Phenylpropensαure Benzalaceticacid Cinnamic acid, (E)- -Phenylpropenoicacid trans-3-Phenyl-2-Propenoic acid trans-beta-Carboxystyrene trans-cinnamic trans-Zimtsαure Zimtsαure TRANS-3-BENZENEPROPENOIC ACID TRANS-3-PHENYLPROPENOIC ACID TRANS-CINNAMIC ACID TRANS-CINNAMYLIC ACID trans-Cinnamic acid/Cinnamic Acid CINNAMIC ACID 99+% NATURAL FCC TRANS-CINNAMIC ACID, 99+% (e)-2-propenoic acid TRANS-CINNAMIC ACID / B-PHENYL ACRYLIC ACID CINNAMIC ACID FOR SYNTHESIS 1 KG CINNAMIC ACID FOR SYNTHESIS 250 G CINNAMIC ACID FOR SYNTHESIS 25 KG CINNAMIC ACID FOR SYNTHESIS 5 G trans-Cinnamic Acid Zone Refined (number of passes:40) trans-CinnaMic acid, standard for GC,>99.5%(GC) Cassia powdcr trans-CinnaMic acid trans-Cinmic acid CINNAMIC ACID 99+% CinnamicAcidGr CinnamicAcidForS trans-Cinnamic acid, 98+% cinnamicacid,(E)-3-phenyl-2-propenoicacid TRANS-CINNAMICACID,REAGENT