D-erythro-sphingosine-d7
- CAS No.
- 1246304-34-6
- Chemical Name:
- D-erythro-sphingosine-d7
- Synonyms
- sphingosine-d7;Sphingosine-d7 (d18:1);D-erythro-sphingosine-d7;D-erythro-sphingosine-d7;D-ERYTHRO-SPHINGOSINE-D7;SPHINGOSINE-D7;(2S,3R,4E)-2-aminooctadec-4-ene-16,16,17,17,18,18,18-d7-1,3-diol
- CBNumber:
- CB82719742
- Molecular Formula:
- C18H30D7NO2
- Molecular Weight:
- 306.535012446
- MDL Number:
- MFCD31806645
- MOL File:
- 1246304-34-6.mol
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D-erythro-sphingosine-d7 Chemical Properties,Uses,Production
Description
Sphingosine-d7 (d18:1) is intended for use as an internal standard for the quantification of sphingosine (d18:1) by GC- or LC-MS. Sphingosine (d18:1) is formed primarily from the breakdown of ceramide.1 Sphingosine (d18:1) inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase.1 Phosphorylation of sphingosine (d18:1) by sphingosine kinases 1 and 2 (SPHK1, SPHK2) produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.2,3,4
References
1. Hannun, Y.A., Luberto, C., and Argraves, K.M. Enzymes of sphingolipid metabolism: From modular to integrative signaling Biochemistry 40(16),4893-4903(2001).
2. Takuwa, Y., Takuwa, N., and Sugimoto, N. The Edg family G protein-
3. Ishii, I., Fukushima, N., Ye, X., et al. Lysophospholipid receptors: Signaling and biology Annu. Rev. Biochem. 73,321-354(2004).
4. Kluk, M.J., and Hla, T. Signaling of sphingosine-
D-erythro-sphingosine-d7 Preparation Products And Raw materials
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D-erythro-sphingosine-d7 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 18521735133 18521732826; | market@aladdin-e.com | China | 25015 | 65 |
| Codow Chemical Co.,Ltd. | 18620099427 | amy@howeipharm.com | China | 17698 | 55 |
| Chengdu Dianchun Technology Co., Ltd | 400-1166-196 18502815961 | cdhxsj@163.com | China | 14623 | 60 |
| Combiphos (Shanghai) Biological Technology Co., Ltd. | 021-65232103 17602124823 | combiphos@vip.qq.com | China | 20005 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Jinan Xinhongtai Chemical Co. LTD | 13000000000 | jnxinhongtai@126.com | China | 19528 | 58 |
| amyjetsci | 027-59626688 18771149750 | sales@amyjet.com | China | 3004 | 58 |
| Hubei Aiputi Bioengineering Co., Ltd. | 17762444226 | d17762444226@163.com | China | 2402 | 58 |