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4-Chloro-2,6-diaminopyrimidine

4-Chloro-2,6-diaminopyrimidine structure

CAS No.: 156-83-2

Chemical Name:: 4-Chloro-2,6-diaminopyrimidine

Synonyms: 2,4-DIAMINO-6-CHLOROPYRIMIDINE;6-CHLORO-PYRIMIDINE-2,4-DIAMINE;NSC 8818;JACS-156-83-2;TIMTEC-BB SBB004123;4-Chloro-2,6-diamino;DiaMino-6-chloropyriMid;Minoxidil EP Impurity B;Minoxidil EP Impurity 3;oro-2,6-diaminopyrimidine

CBNumber:: CB9194300

Molecular Formula:: C4H5ClN4

Molecular Weight:: 144.56

MDL Number:: MFCD00006097

MOL File:: 156-83-2.mol

MSDS File:: SDS

Last updated:2024-04-19 15:29:53

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4-Chloro-2,6-diaminopyrimidine Properties

Melting point	199-202 °C(lit.)
Boiling point	199-202 °C
Density	1.3966 (rough estimate)
vapor pressure	0.0±1.1 mmHg at 25°C
refractive index	1.702
Flash point	218.9±29.6 °C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	slightly soluble
pka	3.66±0.10(Predicted)
form	Solid
color	White to Pale Yellow
Water Solubility	slightly soluble
BRN	118455
InChI	InChI=1S/C4H5ClN4/c5-2-1-3(6)9-4(7)8-2/h1H,(H4,6,7,8,9)
InChIKey	QJIUMVUZDYPQRT-UHFFFAOYSA-N
SMILES	C1(N)=NC(Cl)=CC(N)=N1
CAS DataBase Reference	156-83-2(CAS DataBase Reference)
FDA UNII	83NU5F7ZAS
NIST Chemistry Reference	Pyrimidine, 6-chloro-2,4-diamino-(156-83-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Xn,Xi

Risk Statements

22-36/37/38

Safety Statements

26-24/25

WGK Germany

Hazard Note

Irritant

HS Code

29335995

NFPA 704

	1
2		0

4-Chloro-2,6-diaminopyrimidine price More Price(27)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	C33204	2,6-Diamino-4-chloropyrimidine 98%	156-83-2	5g	$53.3	2024-03-01	Buy
Sigma-Aldrich	C33204	2,6-Diamino-4-chloropyrimidine 98%	156-83-2	25g	$166	2024-03-01	Buy
TCI Chemical	C0811	6-Chloro-2,4-diaminopyrimidine >98.0%(GC)(T)	156-83-2	25g	$58	2024-03-01	Buy
Alfa Aesar	A17780	2,4-Diamino-6-chloropyrimidine, 98%	156-83-2	25g	$0	2021-12-16	Buy
Alfa Aesar	A17780	2,4-Diamino-6-chloropyrimidine, 98%	156-83-2	5g	$38.8	2021-12-16	Buy

Product number	Packaging	Price	Buy
C33204	5g	$53.3	Buy
C33204	25g	$166	Buy
C0811	25g	$58	Buy
A17780	25g	$0	Buy
A17780	5g	$38.8	Buy

4-Chloro-2,6-diaminopyrimidine Chemical Properties,Uses,Production

Chemical Properties

White Cyrstalline Solid

Uses

Definition

ChEBI: 6-chloro-2,4-pyrimidinediamine (4-Chloro-2,6-diaminopyrimidine) is a member of pyrimidines and an organohalogen compound.

Synthesis

2,4-Diamino-6-hydroxypyrimidine (1.00 g, 7.93 mmol) was added to POCl3 (9 mL) and stirred at 97 ℃ for 17 h. The reaction solution was added to ice water slowly and then stirred at 90 C for 1 h. The pH of this solution was adjusted to 8 with NaOH, and then it was extracted with EtOAC (150 mL 3). The combined organic layers were dried with Na2SO4, filtered, and concentrated to give white solid 4-Chloro-2,6-diaminopyrimidine 0.97 g, yielding 85%.

Purification Methods

It recrystallises from boiling H2O (charcoal) as needles; it also crystallises from Me2CO. [Büttner Chem Ber 36 2232 1903, Roth J Am Chem Soc 72 1914 1950, UV: Brown & Jacobsen J Chem Soc 3172 1962, Beilstein 24 H 318, 25 III/IV 2788.]

4-Chloro-2,6-diaminopyrimidine Preparation Products And Raw materials

Raw materials

Phosphorus oxychloride Sodium Methoxide Guanidine nitrate Methyl cyanoacetate

Preparation Products

2,4-DIAMINO-6-ETHOXYPYRIMIDINE 2,4-DIAMINO-6-PIPERIDINOPYRIMIDINE 5-bromo-6-chloropyrimidine-2,4-diamine 6-CHLORO-5-NITROPYRIMIDINE-2,4-DIAMINE

4-Chloro-2,6-diaminopyrimidine Suppliers

Global( 602)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hunan aslsen technology co.,ltd	+8619313031929	aslsd@aslsen.com	China	128	58
Guangzhou Tosun Pharmaceutical Limited	+8618922120635	sales@toref-standards.com	China	1000	58
Zhengzhou Lingzhiyue Technology Co., Ltd	+86-0371-55074660 +86-13783527580	Lingzhiyue@aliyun.com	China	3138	58
Zhejiang Kinso Pharmaceuticals Co., LTD.	+8619857958369	sales@kinsopharma.com	China	27	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2967	58
Zhengzhou Anbu Chem Co.,Ltd	+86-0371-88006763; +8615988602810	sales@anbuchem.com	China	3000	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	994	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7845	58
hebei hongtan Biotechnology Co., Ltd	+86-86-1913198-3935 +8617331935328	sales03@chemcn.cn	China	951	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60

Supplier	Advantage
Hunan aslsen technology co.,ltd	58
Guangzhou Tosun Pharmaceutical Limited	58
Zhengzhou Lingzhiyue Technology Co., Ltd	58
Zhejiang Kinso Pharmaceuticals Co., LTD.	58
Jinan Finer Chemical Co., Ltd	58
Zhengzhou Anbu Chem Co.,Ltd	58
Anhui Ruihan Technology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
hebei hongtan Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60

4-Chloro-2,6-diaminopyrimidine: properties, applications and safety
4-Chloro-2,6-diaminopyrimidine is a white crystalline solid with potential environmental applications and associated safety ri....
Oct 12，2023

What is 4-Chloro-2,6-diaminopyrimidine?
4-Chloro-2,6-diaminopyrimidine(DACP) is a member of pyrimidines and an organohalogen compound. It is a white crystal-like soli....
Jan 16，2020

View Lastest Price from 4-Chloro-2,6-diaminopyrimidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-26	4-Chloro-2,6-diaminopyrimidine 156-83-2	US $5.00 / kg	1kg	≥99%	1000mt/year	Jinan Finer Chemical Co., Ltd
2024-04-26	4-Chloro-2,6-diaminopyrimidine 156-83-2	US $20.00 / kg	1kg	99%	2000kg	hebei hongtan Biotechnology Co., Ltd
2024-04-22	4-Chloro-2,6-Diaminopyrimidine 156-83-2	US $0.00-0.00 / kg	1kg	99%	20tons	Hunan aslsen technology co.,ltd

4-Chloro-2,6-diaminopyrimidine
156-83-2
US $5.00 / kg
≥99%
Jinan Finer Chemical Co., Ltd

4-Chloro-2,6-diaminopyrimidine
156-83-2
US $20.00 / kg
99%
hebei hongtan Biotechnology Co., Ltd

4-Chloro-2,6-Diaminopyrimidine
156-83-2
US $0.00-0.00 / kg
99%
Hunan aslsen technology co.,ltd

4-Chloro-2,6-diaminopyrimidine Spectrum

4-Chloro-2,6-diaminopyrimidine(156-83-2)MS 4-Chloro-2,6-diaminopyrimidine(156-83-2)¹HNMR 4-Chloro-2,6-diaminopyrimidine(156-83-2)¹³CNMR 4-Chloro-2,6-diaminopyrimidine(156-83-2)IR1 4-Chloro-2,6-diaminopyrimidine(156-83-2)IR2 4-Chloro-2,6-diaminopyrimidine(156-83-2)Raman

156-83-2(4-Chloro-2,6-diaminopyrimidine)Related Search:

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4-Chloro-2,6-Diaminopyrimidine-N-Oxide,6-Chloro-2,4-diaminopyrimidine-N-oxide 4-CHLORO-6-MORPHOLIN-4-YLPYRIMIDIN-2-AMINE 6-CHLORO-N4,N4-DIETHYLPYRIMIDINE-2,4-DIAMINE 4-CHLORO-5,6-DIAMINOPYRIMIDINE,6-Chloro-4,5-diaminopyrimidine 2-CHLORO-4,5-DIAMINOPYRIMIDINE

4-Chloropyrimidine Minoxidil 6-CHLORO-N4,N4-DIPROPYL-2,4-PYRIMIDINEDIAMINE

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4-DiaMino-6-chloropyriMidine NSC 8818 DIAMINO-6-CHLOROPYRIMIDINE, 2,4-(SH) 2,4-DIAMINO-6-CHLOROPYRIMIDINE FOR SYNTH 2,6-DiaMino-4-chloropyriMidine 98% DiaMino-6-chloropyriMid 2,4-Diamino-6-chloropyrimidine,98% 4-Chloro-2,6-diaminopyrimidine, 4-Chloro-2,6-diamino-1,3-diazine 2,4-Diamino-6-chloropyrimidine for synthesis 2-AMINO-6-CHLORO-4-PYRIMIDINYLAMINE Pyrimidine,2,4-diamino-6-chloro- 2,4-Diamino-6-Chloro Pyridine 2,6-DIAMINO-4-CHLORO PYRIMIDINE 4-Chloro-2-6-Diaminopyrimide 2,4-Diamino-6-chloropyrimidine, 99+% 2,4-Pyrimidinediamine, 6-chloro- (9CI) 6-Chloro-pyrimidine-2,4-diyldiamine, 4-Chloro-2,6-diaminopyrimidine 2,4-DIAMINO-6-CHLOROPYRIMIDINE/ MINOXIDIL 4-CHLORO-2,6-DIAMINOPYRIMIDINE 98% 4-CHLORO-2,6-DIAMINOPYRIMIDINE (2,4-DIAMINO-6-CHLOROPYRIMIDINE) 4-Chloropyrimidine-2,6-diamine 4-Chloro-2,6-diaminopyrimidine,98% 4-Chloro-2,6-diaminopyrimidine ,99% 2,6-Diamino-4-chloropyrimidine,4-Chloro-2,6-diaminopyrimidine 4-Chloro-2,6-diamino 2,6-Diamino-4-chloropyrimidine ,98% 2,6-Diamino-4-chloropyrimidine (Internal Standard) 4-CHLORO-2,6-DIAMINOPYRIMIDINE 6-CHLORO-PYRIMIDINE-2,4-DIYLDIAMINE 6-CHLORO-2,4-DIAMINOPYRIMIDINE TIMTEC-BB SBB004123 2,4-Pyrimidinediamine, 6-chloro- 2,4-Pyrimidinediamine,6-chloro- 4-Chloro-2,6-pyrimidinediamine 6-Chlor-2,4-diaminopyrimidin(4-2,6) 6-Chloro-2,4-pyrimidinediamine 6-chloro-4-pyrimidinediamine 156-83-2, MFCD00006097, 4-Chloro-2,6-diaminopyrimidine JACS-156-83-2 Minoxidil EP Impurity B 2,6-Diamini-4-chloro pyrimidine 2,4-Diamino-6-chloropyramidine Minoxidil Impurity 2(Minoxidil EP Impurity B） 6-Chloro-2,4-diaminopyrimidine > 2,6-Diamino-4-chloropyrimidine (Internal Standard)@1000 μg/mL in Pyridine 156-83-2, MFCD00006097, 4-ChL oro-2,6-diaminopyrimidine 2,4-DIAMINO-6-CHLOROPYRIMIDINE 6-CHLORO-PYRIMIDINE-2,4-DIAMINE 2,4-Diamino-6-chloropyrimidine (2,4-DACP) Minoxidil EP Impurity 3 DIAMINO-6-CHLOROPYRIMIDINE, 2,4- 156-83-2 C4H5CIN4 HETERO CHLORIDE Pyrimidines Heterocyclic Building Blocks Halogenated Heterocycles