N-Isopropylbenzylamine
- CAS No.
- 102-97-6
- Chemical Name:
- N-Isopropylbenzylamine
- Synonyms
- Isopropylbenzylamine;Benzylisopropylamine;N-BENZYLISOPROPYLAMINE;N-benzylpropan-2-aMine;Benzylamine, N-isopropyl-;n-(1-methylethyl)-benzenemethanamine;AURORA KA-7714;N-Isopropylbenzylamine Crystal;n-(1-methylethyl)-benzenemethanamin;N-(1-Methylethyl)-benzeneMethanaMine hydrochloride
- CBNumber:
- CB9199936
- Molecular Formula:
- C10H15N
- Molecular Weight:
- 149.23
- MDL Number:
- MFCD00008863
- MOL File:
- 102-97-6.mol
- MSDS File:
- SDS
Melting point | 143°C (estimate) |
---|---|
Boiling point | 200 °C(lit.) |
Density | 0.892 g/mL at 25 °C(lit.) |
refractive index |
n |
Flash point | 190 °F |
storage temp. | Store below +30°C. |
solubility | Chloroform (Slightly), Ethy Acetate (Slightly), Methanol (Slightly) |
form | Oil |
pka | 9.77±0.19(Predicted) |
color | Colourless |
BRN | 2638437 |
InChIKey | LYBKPDDZTNUNNM-UHFFFAOYSA-N |
CAS DataBase Reference | 102-97-6(CAS DataBase Reference) |
FDA UNII | 67SYC92FNS |
NIST Chemistry Reference | Benzenemethanamine, N-(1-methylethyl)-(102-97-6) |
EPA Substance Registry System | Benzenemethanamine, N-(1-methylethyl)- (102-97-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
RIDADR | 2735 | |||||||||
WGK Germany | 3 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 8 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29214980 | |||||||||
NFPA 704 |
|
N-Isopropylbenzylamine price More Price(28)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 8.41618 | N-Isopropylbenzylamine for synthesis | 102-97-6 | 100mL | $103 | 2024-03-01 | Buy |
Sigma-Aldrich | 136964 | N-Isopropylbenzylamine 97% | 102-97-6 | 25g | $59.1 | 2024-03-01 | Buy |
TCI Chemical | B1216 | N-Isopropylbenzylamine >98.0%(GC)(T) | 102-97-6 | 25mL | $80 | 2024-03-01 | Buy |
TCI Chemical | B1216 | N-Isopropylbenzylamine >98.0%(GC)(T) | 102-97-6 | 500mL | $400 | 2024-03-01 | Buy |
Alfa Aesar | B23243 | N-Isopropylbenzylamine, 97% | 102-97-6 | 100g | $50.6 | 2024-03-01 | Buy |
N-Isopropylbenzylamine Chemical Properties,Uses,Production
Chemical Properties
CLEAR VERY SLIGHTLY YELLOW TO YELLOW LIQUID
Uses
N-Isopropylbenzylamine, can be used as an intermediate in the synthesis of pharmaceutical compounds,and as a precursor to the manufacture of some drugs. Due to it’s similarity in appearance and physical properties to methamphetamine, it has been recently come under consideration of DEA.
Application
N-Isopropylbenzylamine was used as ligand in the preparation and characterization of bis(cyclopentadienyl)magnesium. It was also used in the synthesis of N-benzylideneisopropylamine-N-oxide.
Preparation
N-benzylisopropylamine is synthesized by the reduction reaction of N-isopropylbenzamide or prepared from benzylamine and acetone by reductive amination reaction.
General Description
N-isopropylbenzylamine is a structural isomer of methamphetamine, is one of the most common adulterants. It forms amine adducts with magnesocene at ambient temperature in toluene.
Cytotoxicity
The toxicity of N-isopropylbenzylamine was evaluated in SH-SY5Y, PC12, and SN4741 cell lines. Cells were treated with 0.3–10 mM N-isopropylbenzylamine for 24 hours, and cell viability was measured using MTT assay. N-isopropylbenzylamine concentration-dependently reduced cell viability in these cells. The IC50 values of N-isopropylbenzylamine on cell viability were 3.47, 1.49, and 3.21 mM for SH-SY5Y cells, PC12 cells, and SN4741 cells, respectively. N-isopropylbenzylamine produced toxicity in cell lines that model neurons. Moreover, the activation of nNOS and the production of intracellular NO might be involved in N-isopropylbenzylamine-induced toxicity in SN4741 cells[1].
References
[1] Peng Xu . “N-isopropylbenzylamine, a methamphetamine mimics, produces toxicity via increasing nitric oxide in vitro.” Toxicology 480 (2022): Article 153337.
N-Isopropylbenzylamine Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
.GZ HONESTCHEM CO.,LTD | +86-15013270415 | honestchemical@foxmail.com | China | 246 | 58 |
Anhui Yiao New Material Technology Co., Ltd | +86-18033737140 +86-17354101231 | sales1@hbganmiao.com | China | 253 | 58 |
Anhui Yisheng Technology Co., LTD | +86-19355901310 +86-19355901310 | alice@ah-yisheng.com | China | 333 | 58 |
Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 436 | 58 |
Anhui Zhongda Biotechnology Co., Ltd | +8615689548120 | linda@zhongda-biotech.com | China | 204 | 58 |
Wuhan Ruichi Technology Co., Ltd | +8613545065237 | admin@whrchem.com | China | 161 | 58 |
Shanghai Likang New Materials Co., Limited | +86-16631818819 +86-17736933208 | 3684455296@qq.com | China | 9311 | 58 |
Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | kathy@hbyinsheng.com | China | 3581 | 58 |
Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 | Ethan@dornechem.com | China | 3137 | 58 |
Hong Kong Excellence Biotechnology Co., Ltd. | ada@sh-teruiop.com | China | 882 | 58 |
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View Lastest Price from N-Isopropylbenzylamine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-22 | N-Isopropylbenzylamine
102-97-6
|
US $10.00 / ASSAYS | 1ASSAYS | 99% | 100kg | Dorne Chemical Technology co. LTD | ||
2024-09-20 | Benzylisopropylamine
102-97-6
|
US $2000.00 / kg | 1kg | 98% | 2000kg | hebei hongtan Biotechnology Co., Ltd | ||
2024-09-19 | N-Isopropylbenzylamine
102-97-6
|
US $20.00 / kg | 1kg | 99.9% | 10000 | Hebei Miaoyin Technology Co.,Ltd |
- N-Isopropylbenzylamine
102-97-6
- US $10.00 / ASSAYS
- 99%
- Dorne Chemical Technology co. LTD
- Benzylisopropylamine
102-97-6
- US $2000.00 / kg
- 98%
- hebei hongtan Biotechnology Co., Ltd
- N-Isopropylbenzylamine
102-97-6
- US $20.00 / kg
- 99.9%
- Hebei Miaoyin Technology Co.,Ltd
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