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3-(4-METHYLBENZYLIDENE)CAMPHOR

3-(4-METHYLBENZYLIDENE)CAMPHOR structure

CAS No.: 36861-47-9

Chemical Name:: 3-(4-METHYLBENZYLIDENE)CAMPHOR

Synonyms: 4-METHYLBENZYLIDENE CAMPHOR;Enzacamene;PARSOL 5000;3-(4-METHYLBENZYLIDINE)CAMPHOR;MBC 95;UV 4MBC;MEXORYLSD;NEO-HELIOPAN;Zinc01481820;EUSOLEX 6300

CBNumber:: CB9366893

Molecular Formula:: C18H22O

Molecular Weight:: 254.37

MDL Number:: MFCD00209662

MOL File:: 36861-47-9.mol

MSDS File:: SDS

Last updated:2024-04-23 17:50:46

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3-(4-METHYLBENZYLIDENE)CAMPHOR Properties

Melting point	66-68°C
Boiling point	198-200 °C
Density	1.064±0.06 g/cm3(Predicted)
RTECS	DT5099565
storage temp.	Inert atmosphere,Room Temperature
solubility	insoluble in H2O; ≥10 mg/mL in DMSO; ≥111.2 mg/mL in EtOH
BRN	9213949
LogP	3.385 (est)
CAS DataBase Reference	36861-47-9(CAS DataBase Reference)
EWG's Food Scores	4-7
FDA UNII	8I3XWY40L9
EPA Substance Registry System	Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-3-[(4-methylphenyl)methylene]- (36861-47-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS09

Signal word

Warning

Hazard statements

H410

Precautionary statements

P273-P391-P501

Hazard Codes

Risk Statements

Safety Statements

22-24/25-36/37

WGK Germany

TSCA

Yes

HS Code

2914399000

NFPA 704

	1
0		0

3-(4-METHYLBENZYLIDENE)CAMPHOR price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHR2805	Methyl Benzylidene Camphor Pharmaceutical Secondary Standard; Certified Reference Material	36861-47-9	400MG	$182	2024-03-01	Buy
Sigma-Aldrich	61547	3-(4-Methylbenzylidene)camphor certified reference material, TraceCERT	36861-47-9	50mg	$116	2024-03-01	Buy
Sigma-Aldrich	1424222	Methyl benzylidene camphor United States Pharmacopeia (USP) Reference Standard	36861-47-9	200mg	$436	2024-03-01	Buy
Cayman Chemical	13840	4-Methylbenzylidene camphor ≥98%	36861-47-9	1g	$120	2024-03-01	Buy
Cayman Chemical	13840	4-Methylbenzylidene camphor ≥98%	36861-47-9	5g	$537	2024-03-01	Buy

Product number	Packaging	Price	Buy
PHR2805	400MG	$182	Buy
61547	50mg	$116	Buy
1424222	200mg	$436	Buy
13840	1g	$120	Buy
13840	5g	$537	Buy

3-(4-METHYLBENZYLIDENE)CAMPHOR Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

3-(4-Methylbenzyliden)camphor is an UV-B absorbing agent in sunscreen cosmetics of the type creams, lotions, lipsticks, sun oils, etc.

Uses

3-(4-Methylbenzylidene)camphor is an organic camphor derivative that is used in the cosmetic industry for its ability to protect the skin against UV, specifically UV B radiation. 4-Methylbenzylidene camphor(4-MBC) a UV-B ray filter, is an endocrine disruptors (ED).

Uses

4-(Methylbenzylidene)camphor (4-MBC), a UV-B ray filter, is an endocrine disruptors (ED).

Biological Activity

4-methylbenzylidene camphor (4-mbc) is an ultraviolet light blocker used in cosmetics and sunscreen preparations that also has estrogenic activities.since the estrogen receptor (er) ligand type can influence transactivation, it is important to obtain information on molecular actions of nonclassical er agonists.

in vitro

previous results of competitive binding assays using cytosolic protein preparations from xenopus hepatocytes demonstrated that 4-mbc could weakly bind to the er. in addition, 4-mbc at a 100 micromol/l was not able to replace estradiol from the receptor completely [1].

in vivo

the estrogen target gene expression in uterus of long evans rats after exposure to 4-mbc was studied. results showed that 4-mbc could altere steady-state levels of mrnas encoding for er, progesterone receptor (pr), and androgen recepto in uterus of 12-wk-old offspring. to evaluate sensitivity to estradiol (e2), offspring were injected with e2, and killed 6 h later. acute up-regulation of pr and igf-i and down-regulation of er and androgen receptor by e2 were reduced in 4-mbc treated rats dose-dependently [2].

References

[1] klann a, levy g, lutz i, müller c, kloas w, hildebrandt jp. estrogen-like effects of ultraviolet screen 3-(4-methylbenzylidene)-camphor (eusolex 6300) on cell proliferation and gene induction in mammalian and amphibian cells. environ res. 2005 mar;97(3):274-81.
[2] s. durrer, k. maerkel, m. schlumpf, et al. estrogen target gene regulation and coactivator expression in rat uterus after developmental exposure to the ultraviolet filter 4-methylbenzylidene camphor. endocrinology 146(5), 2130-2139 (2005).
[3] n. r. janjua, b. mogensen, a. m. andersson, et al. systemic absorption of the sunscreens benzophenone-3, octyl-methoxycinnamate, and 3-(4-methyl-benzylidene) camphor after whole-body topical application and reproductive hormone levels in humans. journal of investigative dermatology 123, 57-61(2004).

3-(4-METHYLBENZYLIDENE)CAMPHOR Preparation Products And Raw materials

Raw materials

Preparation Products

3-(4-METHYLBENZYLIDENE)CAMPHOR Suppliers

Global( 217)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Wuhan ShuEr Biology Technology Co.,Ltd	+86-15629032529	excellentsuppliers@shuerbio.com	China	897	58
Hebei Kingfiner Technology Development Co.Ltd	+86-0086-031185030958 +8615532196582	lisa@kingfinertech.com	China	2987	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	+8617702722807	admin@hbouhuang.com	China	2991	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8823	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5909	58
QINGDAO JADE NEW MATERIAL TECNOLOGY CO.,LTD	+86 13658692156	zandrew@jadenmtc.com	China	221	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Jiangxi Lotchem Co.,Ltd.	+8615270827708	lancetu@jxlotchem.com	CHINA	338	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12568	58

Supplier	Advantage
Wuhan ShuEr Biology Technology Co.,Ltd	58
Hebei Kingfiner Technology Development Co.Ltd	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hebei Guanlang Biotechnology Co., Ltd.	58
Shandong chuangyingchemical Co., Ltd.	58
QINGDAO JADE NEW MATERIAL TECNOLOGY CO.,LTD	58
career henan chemical co	58
Jiangxi Lotchem Co.,Ltd.	58
Zhengzhou Alfa Chemical Co.,Ltd	58

View Lastest Price from 3-(4-METHYLBENZYLIDENE)CAMPHOR manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-29	3-(4-METHYLBENZYLIDENE)CAMPHOR 36861-47-9	US $0.00 / kg	25kg	98.0%	1000TON	Qingdao Truelight functional Material Technology Co., Ltd.
2024-04-28	4-Methylbenzylidene Camphor 36861-47-9	US $70.00 / KG	1KG	99%	1000kg	Hebei Yime New Material Technology Co., Ltd.
2024-04-28	4-Methylbenzylidene Camphor 36861-47-9	US $20.00 / KG	50KG	99%	1000kg	Hebei Yime New Material Technology Co., Ltd.

3-(4-METHYLBENZYLIDENE)CAMPHOR
36861-47-9
US $0.00 / kg
98.0%
Qingdao Truelight functional Material Technology Co., Ltd.

4-Methylbenzylidene Camphor
36861-47-9
US $70.00 / KG
99%
Hebei Yime New Material Technology Co., Ltd.

4-Methylbenzylidene Camphor
36861-47-9
US $20.00 / KG
99%
Hebei Yime New Material Technology Co., Ltd.

3-(4-METHYLBENZYLIDENE)CAMPHOR Spectrum

3-(4-METHYLBENZYLIDENE)CAMPHOR(36861-47-9)¹HNMR

36861-47-9(3-(4-METHYLBENZYLIDENE)CAMPHOR)Related Search:

Trimethyl borate Heptane Dibenzylideneacetone Sodium 1-heptanesulfonate p-Toluic acid

Benzyl bromide BENZYL GLYCIDYL ETHER N,N-Dimethylbenzylamine Camphor Benzyltriethylammonium chloride

Benzyl chloride Benzyltrimethylammonium chloride Chalcone Toluene 2-BENZYLIDENECYCLOHEXANONE

alpha-Hexylcinnamaldehyde [(3E)-3-[[4-[(Z)-[7,7-dimethyl-3-oxo-4-(sulfomethyl)norbornan-2-yliden e]methyl]phenyl]methylidene]-7,7-dimethyl-2-oxo-norbornan-1-yl]methane sulfonic acid Phenylacetone

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4''-METHYLBENZYLIDENE CAMPHOR(MBC 95) NEO-HELIOPAN METHYLBENZYLIDENECAMPHOR MEXORYLSD (+-)-1,7,7-Trimethyl-3-[(4-methylphenyl)methylen]bicyclo[2.2.1]heptan-2-on 3-(4-Methylbenzylidene)-camphor, 99+% Bicyclo2.2.1heptan-2-one, 1,7,7-trimethyl-3-(4-methylphenyl)methylene- MBC 95 (Z)-1,7,7-triMethyl-3-(4-Methylbenzylidene)bicyclo[2.2.1]heptan-2-one 1,7,7-Trimethyl-3-(4-methylbenzylidene)-norbornan-2-one 1,7,7-trimethyl-3-[(4-methylphenyl)methylene]-Bicyclo[2.2.1]heptan-2-one Contralum 6300 Zinc01481820 Methyl Benzylidene Camphor (200 mg) 3-(4-METHYLBENZYLIDEN)CAMPHOR 3-(4'-METHYL)BENZYLIDENE-BORNAN-2-ONE 3-(4-METHYLZYLIDENE)-BRONAN-2-ONE 3-(4-METHYLZYLIDENE)CAMPHOR (3e)-1,7,7-trimethyl-3-[(4-methylphenyl)methylidene]bicyclo[2.2.1]heptan-2-one EUSOLEX(R) 6300 EUSOLEX 6300 NEO HELIOPAN MBC (1S,2Z,4R)-4,7,7-trimethyl-2-[(4-methylphenyl)methylidene]-3-bicyclo[2.2.1]heptanone (2Z)-4,7,7-trimethyl-2-[(4-methylphenyl)methylidene]bicyclo[2.2.1]heptan-3-one 4-Methylbenzylidencamphor 4-Methyl-benzylidene camphor (4-MBC) @100 μg/mL in MeOH 3-(4-Methylbenzylidene)camphor Solution in Methanol/THF/Water, 100μg/mL JADEWIN 4-MBC 36861-47-9 3-(4'-Methylbenzylidene)camphor 3-(4-METHYLBENZYLIDINE)CAMPHOR 4-METHYLBENZYLIDENE CAMPHOR PARSOL 5000 Enzacamene The chemical name is 3-(4-methylbenzene) -camphor UV 4MBC UV ABSORBER TRUELICHT UV 5000 1,7,7-Trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one Azilsartan Impurity 86 36861-47-9 36861-47-1 861-47-9 Aromatics Intermediates & Fine Chemicals Pharmaceuticals cosmetic raw material UV-Absorber